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Biomedical subjects

Andrew Y Wang

Publications and source records attributed to Andrew Y Wang.

3 recordsLinked to original sources

Rectal carcinoids.

PURPOSE OF REVIEW: To provide an updated review of the diagnosis, management, and treatment of rectal carcinoid tumors, with special emphasis on minimally invasive surgical techniques to treat localized disease. RECENT FINDINGS: Carcinoids are morphologically and biologically heterogeneous neuroendocrine tumors that have malignant potential, and are most commonly found in the gastrointestinal tract. The incidence of all carcinoids appears to be increasing, which may reflect improved diagnostic modalities. The rectum is the third most common location for gastrointestinal carcinoids. Recent data have suggested that rectal carcinoids are over-represented in Black and Asian populations. The survival rate for patients with rectal carcinoids is superior to that of carcinoids found elsewhere in the gastrointestinal tract. Tumor size in rectal carcinoids is predictive of metastasis and can reliably guide management. Review of recent literature demonstrates good evidence that localized rectal carcinoids are amenable to local resection. SUMMARY: With widespread colorectal cancer screening, heightened awareness, and improved diagnostic modalities, the incidence of rectal carcinoids should continue to increase. There is evidence that convincingly demonstrates that patients with rectal carcinoids less than 2 cm in diameter, localized to the mucosa or submucosa, may be safely and effectively removed via minimally invasive resection.

Carcinoid Tumor↗

An overview of solid organ transplantation.

Once a medical curiosity, solid organ transplantation is now a commonplace occurrence, with more than 27,000 procedures performed in the United States in 2004 alone. This article offers an overview of the various solid organ transplant procedures to provide a context within which subsequent articles on pulmonary complications can be viewed.

Graft Survival↗

Effectiveness of esophageal dilation for symptomatic cricopharyngeal bar.

BACKGROUND: The cricopharyngeal (CP) bar is an uncommon but important cause of oropharyngeal dysphagia (OPD). Treatment options include CP myotomy, which can be problematic, because CP bars primarily occur in elderly patients who are at higher risk for perioperative complications. The effectiveness of esophageal dilation for patients with symptoms caused by a CP bar is not well studied. METHODS: A review of medical records (1999 to 2002) identified 32 patients with CP bar. Six of these patients who had OPD that could only be attributed to a CP bar underwent EGD and dilation with either over-the-guidewire polyvinyl dilators (5) or a balloon (1). OBSERVATIONS: All 6 patients experienced immediate relief of dysphagia. Five had continued improvement at short-term follow-up (1 to 4 weeks). Three patients still had complete resolution of dysphagia at long-term follow-up (range 8 to 27 months). CONCLUSIONS: CP bar is an important cause of dysphagia in elderly patients. Esophageal dilation of a CP bar can produce long-term relief of dysphagia.

Aged↗