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Biomedical subjects

Andrew J Larner

Publications and source records attributed to Andrew J Larner.

11 recordsLinked to original sources

Late presentation of primary headache associated with sexual activity: is non-invasive angiography worthwhile?

The place of angiography in late presentation of headache associated with sexual activity has not been defined, unlike the situation with acute presentations. In a cohort of patients fulfilling diagnostic criteria for primary headache associated with sexual activity and presenting late (at least three weeks after headache onset), those undergoing non-invasive angiography showed no abnormalities. It is suggested that non-invasive angiography is not routinely indicated in late presentations of headache associated with sexual activity.

Adult↗

Thyroid dysfunction and headache.

An observational study of thyroid function tests performed in patients with headache prior to referral to a neurological clinic found no headache cases attributable to either hypothyroidism or hyperthyroidism. The role of thyroid dysfunction in the aetiology of headache remains uncertain.

Adolescent↗

FAQs: memory loss.

Explore the source record for details and available documents.

Cholinesterase Inhibitors↗

"Frontal variant Alzheimer's disease": a reappraisal.

Two cases of clinically diagnosed sporadic Alzheimer's disease with early and prominent behavioural features (social disinhibition, emotional blunting, stereotyped verbal utterances) sufficient to prompt an initial diagnosis of frontotemporal dementia are presented. It is suggested that the term "frontal variant AD" be used for this clinically defined phenotype, which has also been described in cases of inherited AD associated with certain presenilin-1 gene mutations. This differs from previous usage of the term "frontal variant AD" to describe AD with predominant frontal lobe neuropathological change (although the clinical phenotype may reflect regional distribution of pathology), but parallels the clinical definition of visual agnosic, aphasic and apraxic presentations of AD. The proposed usage would also emphasise differential diagnosis.

Alzheimer Disease↗

Guidelines for the management of headache in primary care: are they being used?

The uptake of guidelines for the management of headache in primary care was assessed using surrogate measures in patients with headache referred to secondary care (number of prior general practitioner attendances and medications prescribed). The results suggest that headache guidelines are seldom, if ever, applied in this geographical location.

Ambulatory Care Facilities↗

Caleb Hillier Parry (1755-1822): clinician, scientist, friend of Edward Jenner (1749-1823).

This article summarizes briefly the life and work of Dr Caleb Hillier Parry (1755-1822), a friend of Dr Edward Jenner. He made original clinical observations, including the bradycardic effect of carotid artery compression, and the association of thyroid enlargement with cardiac disease. He also undertook experimental work and published extensively, including the first book devoted to angina.

Angina Pectoris↗