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Biomedical subjects

Amor Khachemoune

Publications and source records attributed to Amor Khachemoune.

At least 19 recordsLinked to original sources
PubMed2006

Infantile perineal protrusion.

Infantile perineal protrusion, a relatively newly recognized condition, is underreported in both the dermatologic and pediatric literature. The name "infantile perineal protrusion" has evolved based on the typical anatomic location, morphologic features, and prevalence in prepubertal children. It occurs in 3 settings: constitutional (sometimes genetic or familial); functional (after constipation, diarrhea, or other irritant exposure); or associated with lichen sclerosus et atrophicus. Recognition of infantile perineal protrusion by dermatologists and pediatricians has many implications regarding proper diagnosis and management. The condition may be mistaken for condyloma acuminata or as a sign of trauma, leading to an erroneous investigation of sexual abuse. In this article, we report two new cases and make a thorough review of the literature to elucidate the mechanisms, diagnosis, classification, and management to clarify this often misdiagnosed condition.

Female↗
PubMed2006

Mycetoma : a review.

Mycetoma is a chronic granulomatous infection that is present worldwide and endemic in tropical and subtropical regions. The infection is caused by the traumatic inoculation of a fungus (eumycetoma) or a bacterium (actinomycetoma) and generally remains localized, causing cutaneous and subcutaneous tissue swelling, nodule formation, and drainage through sinus tracts. This review details the history of mycetoma, which may date as far back as the Byzantine period (300-600 AD), the epidemiology of the disease, which is characterized by an endemic region located between the latitudes of 15 degrees south and 30 degrees north, and the clinical presentation and treatment of mycetoma, focusing on the differences between eumycete and actinomycete infections. Diagnosis is established by identifying the type of grains found in the discharge, which guides treatment. Mycetoma caused by bacteria can usually be managed effectively with antibacterial medication alone, while infections with fungi require antifungal medication and surgery. Without proper treatment, mycetoma can lead to deformity, amputation, and death.

Actinomycetales Infections↗
PubMed2006

Psoriasis: disease management with a brief review of new biologics.

Psoriasis is a chronic inflammatory dermatosis that affects 0.6% to 4.8% of the population and is seen in all ages. The disease is characterized by a well-demarcated, salmon-colored plaque surmounted by silver-white scales. Given the chronic nature of the disease, goal of treatment is to induce and maintain remission, with minimal short and long-term side effects from therapy. Most agents can be used alone or in combination with other treatment modalities.

Anti-Inflammatory Agents↗
PubMed2006

Crusted scabies: a clinical review.

Crusted scabies, a rare variant of classical scabies, is a highly contagious condition in which the skin is infected with thousands to millions of mites. It can be defined as a generalized severe scabies infestation usually affecting immunocompromised patients. The diagnosis is becoming more relevant with the increasing use of immunosuppressive medications and the HIV epidemic. To date, more than 200 cases have been reported in the literature. We present a review of the pathogenesis, clinical manifestations, diagnostic considerations, and therapeutic options.

Administration, Oral↗
PubMed2006

Assessing phytophotodermatitis: boy with erythema and blisters on both hands.

Phytophotodermatitis (PPD) is a phototoxic reaction which occurs when the skin comes in contact with a photosensitizer and is subsequently exposed to radiation. PPD is often seen in people handling furocoumarin-containing products, such as agricultural workers, bartenders, florists, and gardeners. It may also be seen in beachgoers, athletes, and children. The pattern of the lesions usually resembles streaks; the hands and mouth are most commonly affected due to eating and handling of the offending furocoumarin-containing agents.

Adolescent↗
PubMed2006

Tinea versicolor.

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Administration, Cutaneous↗
PubMed2006

Dermographism.

Explore the source record for details and available documents.

Adult↗
PubMed2006

Pemphigus foliaceus: a case report and short review.

Pemphigus foliaceus (PF) is a rare autoimmune blistering disease presenting in endemic and sporadic forms. The typical presentation is recurrent shallow erosions in a seborrheic distribution. We present a case of a 58-year-old woman with PF who was successfully treated with a combination of oral corticosteroids and dapsone. We also provide a concise review of the literature and discuss the etiology, clinical features, diagnosis, and management of PF.

Anti-Inflammatory Agents↗
PubMed2006

Hereditary angioedema.

Hereditary angioedema (HAE) is a rare autosomal dominant disorder caused by a C1-inhibitor deficiency. It is characterized by potentially life-threatening recurrent episodes of angioedema of the skin and mucosa. Several recent studies have further elucidated the immunology of HAE implicating bradykinin, the key mediator of the contact system. This article reviews the pathophysiology, subtypes, and clinical features of HAE. Therapeutic approaches for various clinical situations (emergency and prophylactic regimens) are also discussed.

Aminocaproates↗