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Biomedical subjects

Alan Patrick Ainsworth

Publications and source records attributed to Alan Patrick Ainsworth.

7 recordsLinked to original sources

[Transgastric necrosectomy by open surgery in necrotising acute pancreatitis].

INTRODUCTION: Conventional surgery for necrotising acute pancreatitis is often associated with high mortality and morbidity rates. The aim of this study was to describe the initial experience with a new and presumed lesser invasive surgical procedure. MATERIAL AND METHODS: The outcome of patients who underwent transgastric necrosectomy and subsequent marsupialisation due to necrotising pancreatitis was registered. RESULTS: Seven patients (five males, two females) with a median age of 47 years (range 32-62 years) had surgery. The reasons for pancreatitis were: gallstones (n = 4), idiopathic (n = 2) and alcohol (n = 1). The median time from onset of symptoms to surgery was 40 days (range 29-90 days). Four patients (57%) had an uneventful post-operative stay. Three patients (43%) had one or more complications requiring invasive therapy. Two of these patients needed repeated surgery. The median postoperative hospitalisation was 18 days (range 10-65 days). There was no post-operative mortality. At a three-month follow-up, one patient had exocrine pancreatic insufficiency, and one patient had both exocrine pancreatic insufficiency and diabetes mellitus. CONCLUSION: Transgastric necrosectomy seems to be associated with a low risk of complications for selected patients with necrotising acute pancreatitis. However, further experience with the procedure is needed in order to draw valid conclusions.

Adult↗

[Diagnostic imaging modalities for gallstones--where are we heading?].

External ultrasonography is the cornerstone imaging modality for the diagnosis of gallbladder stones, and it is unlikely that it will be replaced by other examination methods. Due to the complications associated with endoscopic retrograde cholangiopancreatography (ERCP), endoscopic ultrasonography and magnetic resonance cholangiopancreatography should replace this examination method in patients with a low probability of common bile duct stones. However, ERCP may be used as the first examination method in selected patients with a high probability of bile duct stones.

Cholangiopancreatography, Endoscopic Retrograde↗

[Cholecystectomy in Denmark 1989-2003].

INTRODUCTION: The aim of this study was to describe the cholecystectomy rate in Denmark in the last 15 years, since the introduction of laparoscopic cholecystectomy might have had an influence on it. MATERIALS AND METHODS: An analysis was done of data from the mandatory Danish National Patient Registry, which covers all public hospitals in Denmark. All cholecystectomies performed from 1989 to 2003 in the various hospitals were registered. Open and laparoscopic operations were registered separately. In addition, the number of patients who were operated on for acute cholecystitis from 1996 to 2003 was registered. RESULTS: An increase in the cholecystectomy rate was observed, from 67/100,000 inhabitants in 1989 to 143/100,000 inhabitants in 2003 (p < 0.05). The increase was due mainly to the number of laparoscopic procedures, which comprised 81% of all cholecystectomies in 2003. The proportion of patients who were operated on for acute cholecystitis decreased from 14% in 1996 to 12% in 2003 (p < 0.05). DISCUSSION: The increasing cholecystectomy rate in Denmark from 1989 to 2003 is probably due to the fact that more patients are having surgery for painful gallbladder stones.

Cholecystectomy↗

[Endoscopic ultrasonography].

Despite being a well-described diagnostic procedure for more than ten years, endoscopic ultrasonography (EUS) is not generally widespread in Denmark. This review deals with the present indications for EUS. For some diseases, EUS has found its precise place in the diagnostic strategy. However, in other diseases, it is not yet clear where to put EUS in relation to other diagnostic procedures.

Endosonography↗

[An analysis of the demand of endoscopic ultrasonography in Denmark].

INTRODUCTION: Endoscopic ultrasonography (EUS) has been available in Denmark for about 10 years. Capacity problems can occur, because only a few departments perform this procedure. The aim of the present study was to analyse the demand for EUS in Denmark. METHODS: Questionnaires (140) were sent out to departments in Denmark, which were presumed to refer patients for EUS on a regular basis. RESULTS: One-hundred and seventeen questionnaires (84%) were returned. Twenty-three (20%) of the departments that returned the questionnaire stated that they never referred patients for EUS. The main reason was that patients, for whom EUS was considered necessary, were rarely treated in these departments (15 departments). Seventy departments (74%) referred 0-2 patients for EUS monthly. Twenty-one departments (22%) had problems in obtaining the number of investigations needed. There were significantly fewer problems in obtaining the desired number of investigations, if EUS was performed in the home county (p = 0.012). Thirty-eight per cent of the departments stated that more patients would be referred for EUS, if the procedure became more available in the future. DISCUSSION: There seems to be too small a capacity for EUS in Denmark. Whether the capacity should be increased by establishing new centres or by extending the present ones is unknown. Both solutions have benefits and drawbacks.

Denmark↗