Biomedical subjects

Agavni Petrosyan

Publications and source records attributed to Agavni Petrosyan.

4 recordsLinked to original sources

PubMed2005

Neural cross-correlation and signal decorrelation: insights into coding of auditory space.

The auditory systems of humans and many other species use the difference in the time of arrival of acoustic signals at the two ears to compute the lateral position of sound sources. This computation is assumed to initially occur in an assembly of neurons organized along a frequency-by-delay surface. Mathematically, the computations are equivalent to a two-dimensional cross-correlation of the input signals at the two ears, with the position of the peak activity along this surface designating the position of the source in space. In this study, partially correlated signals to the two ears are used to probe the mechanisms for encoding spatial cues in stationary or dynamic (moving) signals. It is demonstrated that a cross-correlation model of the auditory periphery coupled with statistical decision theory can predict the patterns of performance by human subjects for both stationary and motion stimuli as a function of stimulus decorrelation. Implications of these findings for the existence of a unique cortical motion system are discussed.

Acoustic Stimulation↗

PubMed2004

A population study of the precedence effect.

Data are reported from a population of untrained individuals under lag- and single-click conditions in a discrimination suppression precedence-effect task. The cue to be discriminated was an interaural level-difference (ILD). Each of 91 observers completed 10 runs in a two-interval forced-choice design under a lag-click condition and three runs under a single-click condition. Stimuli were 125-micros rectangular pulses and the interclick interval was 2 ms. Observers were randomly assigned to three groups of approximately 30. Each group was then tested at one stimulus intensity (43, 58, or 73 dB). Mean threshold within each group was greater than 15 dB for the lag-click condition and 6 dB for the single-click condition, although there was substantial interobserver variability. In contrast to [J. Acoust. Soc. Am. 114 (2003) 420] who reported a strong effect of intensity on lag-click ITD discrimination, no effect of intensity was observed on lag-click ILD thresholds. Analysis of over 50,000 near-threshold trials from 302 observers pooled across studies showed a spatial asymmetry in response patterns and a small, but statistically significant effect of gender. A model is proposed which shows that decay of sensory memory and increases in auditory filter bandwidths with intensity may predict the different findings for ILD versus ITD lag-click thresholds.

Acoustic Stimulation↗

PubMed2004

A detection-theoretic model of echo inhibition.

A detection-theoretic analysis of the auditory localization of dual-impulse stimuli is described, and a model for the processing of spatial cues in the echo pulse is developed. Although for over 50 years "echo suppression" has been the topic of intense theoretical and empirical study within the hearing sciences, only a rudimentary understanding of its mechanisms has emerged. In this article, psychometric functions and results from matching studies are used in developing a model that specifies the perceived position of the echo pulse as a normal deviate, with an expectation that is a logistic function of the echo delay and a variance that depends on interaural time difference. Loss of information in the echo event is quantified as a decline in the efficiency with which the binaural system receives information from the lag impulse.

Attention↗

PubMed2002

Concurrent motion detection based on dynamic changes in interaural delay.

The ability to detect a dynamic change in the interaural delay of a pure tone in the presence of a distracter tone of a different frequency was investigated in four conditions: (1) a control condition in which no distracter tone was present, (2) the distracter tone was stationary (fixed interaural delay), (3) the distracter had an interaural delay that changed in the same direction as that of the target tone, i.e., concurrent auditory motion in the same direction, and (4) the distracter had an interaural delay that changed in a direction opposite to that of the target tone, i.e., concurrent auditory motion in opposite directions. In a cued single-interval two-alternative forced-choice design, the observer had to determine if the target tone had a constant or dynamic interaural delay. The target was a 500-Hz tone and the distracter was a tone with a frequency of 300, 510, 550, 600, 800, or 1000 Hz. Detection was also examined for a range of stimulus durations, rates of change in interaural delay (i.e., velocity), and extent of change in interaural time difference (i.e., 'distance'). Results showed that the best performance (highest d') was associated with the no-distracter condition, followed by the stationary-distracter, opposite-direction, and same-direction conditions, respectively. Detection improved with increasing frequency difference between distracter and target tones, but was nonetheless lower than that associated with the no-distracter condition, even when the distracter frequency was several critical bands removed from the target frequency.

Auditory Perception↗