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Abdulbari Bener

Publications and source records attributed to Abdulbari Bener.

52 records · Page 3Linked to original sources

Growth pattern of Qatari preschool children.

AIM: To compare the growth patterns of Qatari preschool children aged 0-5 years with the growth reference charts developed by the American National Center for Health Statistics and Centers for Disease Control and Prevention (NCHS/CDC). METHODS: The demographic data of weight, height, and age were collected in a cross-sectional study among 8,231 Qatar children aged 0-5 years. There were 4,136 (50.2%) boys and 4,095 (49.8%) girls. The children were selected by a cross-sectional stratified random sampling procedure based on the stratification on the location and a socio-economic status. The measured data were compared with NCHS/CD growth charts. RESULTS: The boys were significantly taller than girls in age groups 0-6 months (58.3+/-4.1 vs 57.4+/-4.0 cm, respectively; p<0.001), 6-12 months (66.7+/-4.0 vs 66.2+/-5.1 cm, respectively; p=0.018), 48-54 months (102.1+/-3.6 vs 100.9+/-3.9 cm, respectively; p<0.001), and 54-60 months (106+/-4.8 vs 103.1+/-3.5 cm, respectively; p<0.001). The boys had significantly heavier weight pattern than the girls in all age groups (p<0.001). The height for boys ranged from 58.3 cm to 106 cm, and for girls from 57.4 cm to 103.1 cm. The weight range for boys was 5.4-17.6 kg and 5.1-16.8 kg for girls. More than 11% of the children had stunted growth, 5.4% of the children were taller than normal for their age, 4.4% of the children were undernourished, and 0.6% were severely undernourished. CONCLUSION: A combination of height for age (as an indicator of stunting) and weight for height (as an indicator of wasting) showed - that a sizeable proportion of Qatari children had normal or slightly above normal nutritional status. The growth pattern we presented may suffice as a standard for monitoring the growth of Qatari children in particular, and those in the Gulf region in general.

Body Height↗

Clinical and histologic studies of a Qatari family with myofibrillar myopathy.

The current study reports the first family with confirmed myofibrillar myopathy MFM in the Middle East and the third family worldwide. This study highlights the importance of considering MFM in young patients presenting with idiopathic cardiomyopathy, arrhythmia or atrioventricular block in the Gulf states. This is the first report that presented 2 different types of cardiomyopathy and 2 different indications of permanent pacemaker placement in the same generation of a family with MFM. This report studies a Qatari family consisting of one brother and 3 sisters. The brother had restrictive cardiomyopathy at the age of 16 years. One sister underwent heart transplantation for severe hypertrophic cardiomyopathy at the age of 15 years, the other sister had permanent pacemaker for complete heart block at the age of 21 years. This report is focused mainly on the clinical presentation and investigations carried out for the brother including echocardiogram, cardiac catheterization, cardiac and skeletal muscle biopsy, and electromyography and electrophysiology studies. The study findings support the diagnosis of MFM.

Adult↗

Cardiovascular manifestations of myofibrillar myopathy.

Myofibrillar myopathy (MFM) is a rare autosomal dominant disorder characterized by cardiac and skeletal myopathy. Either of these can dominate in the clinical picture. It is associated with cardiomyopathy, arrhythmia and/or atrioventricular (AV) conduction defects. Myofibrillar myopathy is often an overlooked disorder because of its variable clinical presentation. We highlight the various cardiovascular manifestations of MFM that have been reported in the literature and address the importance of considering this syndrome in young patients presenting with idiopathic cardiomyopathy and/or AV conduction defects.

Cardiomyopathy, Restrictive↗

Management of idiopathic sudden sensorineural hearing loss: experience in newly developing Qatar.

Idiopathic sudden sensorineural hearing loss is a medical emergency that requires urgent diagnosis and treatment, and the adaptation of a proper protocol for management is a priority. In most cases, such treatment is rather controversial and depends on a variety of factors. The aim of this study was to determine and identify as early as possible those factors that play the important role in the prognosis of the condition, to describe the experience, and to suggest a treatment protocol that can be adopted in a tertiary hospital, such as Hamad General Hospital. Our study was retrospective and descriptive. It was conducted in the ear, nose, and throat outpatient clinics at Hamad General Hospital and the ear, nose, and throat wards at Rumailah Hospital. We enrolled a total of 21 patients with idiopathic sudden sensorineural hearing loss. The treatment protocol that was adopted--consisting of high-dose steroid therapy, full-dose antiviral drug (acyclovir), and a histamine analog, betahistine--resulted in hearing improvement in 57.4% of cases. Then the possible good and bad prognostic factors were discussed. The results of our study revealed that the steroid therapy protocol practiced in Qatar resulted in hearing improvement in patients with idiopathic sudden sensorineural hearing loss. Good prognostic factors include early diagnosis, marked reduction of symptoms, and improved shape of the audiometric curve.

Acyclovir↗

Birth prevalence and pattern of osteochondrodysplasias in an inbred high risk population.

BACKGROUND: Define the pattern and birth prevalence of the different types of osteochondrodysplasias in newborn infants in the United Arab Emirates (UAE) population, which is highly inbred and where termination of pregnancy is not accepted. METHODS: All infants with a birth weight of 500 gm and above in the three hospitals in Al Ain Medical District of the UAE were studied prospectively over a period of 5 years. For each live birth or stillbirth with suspected skeletal dysplasia, a detailed clinical and radiological examination was carried out. Pregnancy history and information regarding parental age, ethnic origin, family history, and level of consanguinity were obtained and a pedigree was constructed. RESULTS: Among the 38,048 births during the study period, 36 (9.46/10,000 births) had some type of skeletal dysplasia. Eighteen cases were attributed to autosomal recessive genes (4.7/10,000 births), 10 were due to apparent new dominant mutations (2.62/10,000), five were autosomal dominant type (1.3/10,000) and one was X-linked dominant type (0.26/10,000). In three cases, inheritance was unknown. The most common recessive type of skeletal dysplasia in our series was fibrochondrogenesis (1.05/10,000), followed by chondrodysplasia punctata (0.78/10,000). The birth prevalence rate of skeletal dysplasia doubled in the last 2 years of the 5-year observation period (6.74/10,000 in 1996 vs. 12.86/10,000 in 1999, and 13.45/10,000 in 2000). This increase involved cases caused by new dominant mutations, and occurred mainly in the first half of 1999. CONCLUSION: This prospective study has identified a high birth prevalence of skeletal dysplasia, and risk factors are postulated. These findings represent an accurate birthprevalence figure and a useful baseline for this group of birth defects in the UAE.

Adult↗

Epidemiology, presentation, management and outcome of candidemia in a tertiary care teaching hospital in the United Arab Emirates, 1995-2001.

Sixty episodes of candidemia among hospitalized patients in the United Arab Emirates (0.77/1000 discharges) in 1995-2001 were identified through case retrieval. All patients had malignancy (65%) or serious non-malignant disease (35%). Candida albicans accounted for 45% of isolates. Non-C. albicans Candida species occurred more frequently than C. albicans in adults (67%), hematologic-malignancy patients (58%), and cases of breakthrough candidemia (83%) and were prevalent overall in 2000-2001 (67-73%). C. tropicalis was identified in 15% of cases, C. glabrata in 5%, C. parapsilosis in 5%, C. inconspicua in 2%, C. famata in 2% and C. lusitaniae in 1%. Delayed diagnosis or treatment was common, as was Karnofsky scale < or = 40%, septic shock, and inadequate dosage or duration of antifungal drug therapy. Crude mortality was 50%, and mortality attributable to candidemia was 30%. Univariate analysis indicated patients were more likely to die (odds ratio for death [95% CI]) if they had been stationed in the intensive care unit (ICU) (4.76 [1.31-17.2]), had a Karnofsky scale < or = 40% (38.76 [4.66-322.47]), or suffered septic shock (9.88 [2.9-33.65]). They were more likely to survive in cases with concomitant bacteremia (0.25 [0.07-0.91]), adequate antifungal dose (0.28 [0.08-0.94]), and removal of central lines (0.26 [0.07-0.95]). The high association of bacteremia with candidemia (70% of cases) is unusual. The apparent survival benefit experienced by patients who had bacteremia (odds ratio for survival on multivariate analysis = 2.40 [0.28-20.17], P < 0.03) is novel.

Adolescent↗

Strategy to improve road safety in developing countries.

OBJECTIVE: To review the road safety situation in developed and developing countries compared with the Arabian Gulf countries and suggest a strategy to improve it. The role of road engineers in reducing accidents is highlighted. METHODS: This is a retrospective study of road traffic accidents (RTAS) for a period from 1988 to 1998 in Arabian Gulf Countries. The data was taken from the Directorate of Traffic and Ministry of Health records in Gulf Countries. Additional data was obtained from other sources including the World Health Organizations Statistics Annuals, International Road Federation, Transport Road Research Laboratory and accident facts publications. Overall fatality and injury rates of RTAs were calculated. RESULTS: The lack of reliable data is a serious problem in most of the developing countries. It is quite reasonable to assume that the incidence of accidents is much larger than actually reported. A comparison of vehicle ownership levels and safety parameters in both developed and developing countries is presented to highlight the relative seriousness of the road safety situation in different countries. The fatality rates (per population and per vehicles) are selected for comparison purposes from developed and developing countries. CONCLUSION: Road traffic accidents continue to be a major cause of mortality and morbidity in the Arabian Gulf Countries leading to substantial wastage of life and national resources. Further investigation is essential and will require close inter-sectoral collaboration between, traffic police, health, law, and transport authorities. Developing a research strategy for prevention will reduce casualties and death on the road.

Accidents, Traffic↗

Clinicopathological pattern of colorectal cancer in the United Arab Emirates.

OBJECTIVE: The aim of this study is to define the epidemiology of the colorectal cancer in the United Arab Emirates and compare it with the other Gulf States and developed countries. METHODS: This study is a retrospective descriptive study that includes 114 patients who underwent surgeries for colorectal carcinoma at Al-Ain and Tawam Hospitals in the United Arab Emirates during the period 1985 through to 1998. These patients were under medical follow up for a mean period of 24 months (range 6-120 months) Both univariate and multivariate analyses were performed to assess predictors of recurrence and survival. The survival curves were computed by using Kaplan-Meier method. RESULTS: Mean annual incidence was 12 patients/year. There were 77 males (67.5%) and 37 females (32.5%). The mean age at the time of diagnosis was 46.6 11.8 years with the median age of 47 years. The mean overall survival time was 63.7 7.7 months. The survival time was shorter for younger patients, those with palliative resection, lymph node metastasis and peritoneal nodules. In multivariate Cox proportional hazards analysis the hazard ratio for positive lymph nodes was 2.30 (95% confidence intervals (CI) 1.22-4.50) as compared to negative nodes and a hazard ratio of 0.52 (95% CI 0.32-0.89) for Dukes stages A and B as compared to Stage C. CONCLUSION: Colorectal carcinoma is not a common disease in the United Arab Emirates. In general, the incidence pattern is similar to that of neighboring Gulf and Arab countries. The main reasons of low incidence of colorectal cancer in these countries could be due to the dietary factors, which is intake of more fruit and vegetables.

Adolescent↗

Study of HER2/neu status in Qatari women with breast carcinoma.

OBJECTIVE: The study is aimed at determining the prevalence of HER2/neu overexpression in Qatari women with breast cancer and to assess the survival in patients with HER2/neu positive tumors. METHODS: This is a retrospective study of clinical data of 70 Qatari female patients diagnosed with breast cancer during the period 1991 through to 2001, at Hamad Medical Corporation, Doha, Qatar. We also performed a retrospective review of breast tissue sample for those patients using paraffin sections and applying immunohistochemistry staining-[Hercep test (DAKO Inc)] to determine the HER2/neu status. RESULTS: Eighteen patients (26%) were HER2/neu positive (2+ and 3+) with a mean age at diagnosis of 49.3years, and 52 (74%) were negative (0 and 1+) with mean age at diagnosis of 46.6 years. Of the patients with positive HER2/neu, 5 (28%) had a relapse of the disease and 4 (22%) died of the disease during follow up. Of the patients with HER2/neu, negative test 9 (17%) had a relapse of the disease and 10 (19%) died of the disease. The median survival function at mean of covariates for HER2/neu positive patients was 26 months, and for HER2/NEU negative patients was 28 months. CONCLUSION: The prevalence of HER2/neu over expression in Qatari female with breast cancer in this study is 26%, but due to a small sample size it may not reflect really the prevalence. Patient with HER2/neu positive were older at diagnosis than patients with HER2/neu negative, also they had higher relapse rate and mortality. Median survival function was better for HER2/neu negative patients.

Adult↗

Obesity and low back pain.

Obesity and low back pain (LBP) are common health problems among patients attending Primary Health Care (PHC) in general practice at the United Arab Emirates (UAE). The objective of this study was to determine whether obesity is associated with low back pain. A cross-sectional face-to-face interview questionnaire survey was conducted. The questionnaire was a modified version of the Roland-Morris Scale for evaluating back disability. The interviews were conducted in Arabic by qualified nurses. A multi-stage stratified sample 1,103 UAE national aged 25-65 years, who attended PHC clinics for any reason, were invited to participate but only 802 subjects were eligible to be included for the statistical analysis. The data were analyzed using univariate and multivariate statistical methods. Of the 802 subjects, 428 (53.4%) were males and 374 (46.6%) were females. The mean age of the males was 40.5 +/- 11.5 years and females was 38.2 +/- 10.5 years (p = 0.004). The mean BMI of the males was 26.4 +/- 7.4 and females was 27.8 +/- 5.6 (p = 0.002). The overall prevalence of LBP in the present study was 64.9% (95% confidence interval, 61.0-68.8) and respectively, 56.1% in males and 73.8% in females. The results revealed that there was association between BMI and some socio-demographic variables with the respect of with low back pain. Back pain had more influence on the life style habits on females than in males. Stepwise multiple regression analysis showed that only age (p < 0.0001), educational level (p = 0.001), gender (p = 0.002), place of living (p = 0.019), BMI (p < 0.0001), and housing condition (p = 0.02) had significant effect on the presence of LBP in patients. The present study showed that obesity is moderately associated with low back pain.

Adult↗

The pattern of indoor and outdoor respiratory allergens in asthmatic adult patients in a humid and desert newly developed country.

BACKGROUND: Studies have shown that allergens are very important sensitizing agents in patients with asthma. Respiratory disorders such as asthma and allergic rhinitis are common in the State of Qatar. OBJECTIVE: To characterize the most frequent indoor and outdoor respiratory allergens involved in bronchial asthma and allergic rhinitis in the State of Qatar. DESIGN: A hospital-based prospective study conducted. SETTING: Allergy Laboratory at the Hamad General Hospital and Hamad Medical Corporation, Doha, State of Qatar. PATIENTS: Adult patients over 12 years of age diagnosed with bronchial asthma and/or allergic rhinitis who were referred for allergy skin pick test. 1106 adult patients recruited with respiratory diseases of suspected allergic origin who attended Allergy Clinic at the Hamad General Hospital, during three years from January 2001 to April 2003. Total of 1106 whom 607 were females (54.9%) and 499 were males (45.1%) and their mean was age 30 years (12-48). METHODS: Skin Prick Test [SPT] was performed on 1106 patients for common allergens whom The blood sample was taken for measuring specific IgE concentration. RESULTS: There were 1106 patients studied and 569 patients (51.4%) had positive skin prick test. All patients expressed clinical allergy, 464 patients (52%) had asthma and rhinitis, 286 patients (32%) had rhinitis alone and 137 patients (15%) had asthma alone. The population sample had a higher prevalence of diagnosed asthma among females (32.7%) than in males (29.8%) and also skin conditions such as eczema, pruritus, and urticaria higher in females (9.1%%) than males (7.0%). Similarly, males had higher prevalence of allergic rhinitis (86.0%) than in females. There were 318 (55.9%) patients whose asthma developed before they were 10 years old. The percentage of asthmatic patients with a positive family history of asthma was 44%. The most common allergens detected in order of frequency were Dermatophagoides Pteronyssimus (Der p l) in 248 patients (41.6%), Dermatophagoides Farinae (Der f l) in 220 patients (36.9%), Cockroach allergen (Bla g l) in 192 patients (32.2%). The study showed that females are more exposed to pollen, grasses and tress, but males are mostly exposed to mites and insects. Furthermore, Molds and Yeast were common among males. CONCLUSION: In conclusion, the frequency of indoor and outdoor allergens in state of Qatar, based on skin prick test study showed the dominance of house dust mites, pollen, grasses which are more or less same to other countries with similar and even with different climate. Reduced exposure to these agents will help control raising severity of these disease.

Adolescent↗

Road traffic accidents in the United Arab Emirates: trends of morbidity and mortality during 1977-1998.

High rates of serious road traffic accidents (RTAs) have been reported for several Arabian Gulf countries, including the United Arab Emirates (UAE). in recent years. This study aims to describe quantitatively the morbidity and mortality from RTAs in the UAE, to identify their trends during the period 1977-1998, to compare the results with those of developed countries, and to evaluate the information available on possible causes with a view to identifying the most useful direction for future research. Data were obtained from UAE's police and health sources and, for international comparison, from WHO Statistics reports and the published literature. Overall and cause-specific fatality and injury rates of RTAs were calculated. Estimates of trends were achieved by using linear regression. The characteristics of road users injured or killed were also analysed. The results revealed that during the period 1977-1998, the rates of RTAs per 100,000 population and per 100,000 motor vehicles declined in the UAE by a trend component of -56.3 (P < 0.001: R2 = 0.69) and -521.8 (P<0.001; R2=0.92), respectively. RTA fatality and injury rates based on the same denominators also declined by -1.1 (P<0.001; R2 = 0.56) and -13.3 (P < 0.001; R2 = 0.47); and by -3.8 (P < 0.02; R2 = 0.23) and - 90.0 (P < 0.001; R2 = 0.59), respectively. Paradoxically, however, except for a short period (1977-1985), a steady increase in the risk of injury and death in each RTA accompanied these declines. Between 1985 and 1998 the severity rate (the ratio of fatalities and injuries per 1,000 RTAs) more than tripled in the UAE. The UAE's rates were high when compared with a number of selected countries. The cause for the increasing severity of RTAs is not clear but the most likely cause could lie in speeding, careless driving, the changing vehicle mix on the roads and the standard of immediate care available for victims. Further investigation is essential and will require close collaboration between police and health authorities.

Accidents, Traffic↗

Temporal lobe epilepsy in children: etiology in a cohort with new-onset seizures.

PURPOSE: The aim of this study was to characterize the incidence and etiology of temporal lobe epilepsy (TLE) in a community-based cohort of children with new-onset disease. METHODS: A community-based cohort of 30 children with TLE was studied. The patients had new-onset disease before age 14 years between 1995 and 1999. They underwent clinical, EEG, and magnetic resonance imaging investigations. RESULTS: The patients could be divided in three main groups according to likely etiology, as suggested by Harvey et al. (Neurology 1997;49:960-8). Group 1 consisted of eight (26.7%) children with malformations or long-standing, nonprogressive tumors (developmental TLE). Arachnoid cysts were found in three, dual pathology [cortical dysplasia and hippocampal sclerosis (HS)] in one, and focal cortical dysplasia with glioproliferative changes in one patient. Dysembryoplastic neuroepithelial tumor was responsible for the epilepsy in one, and ganglioglioma, in two children. Group 2 consisted of seven (23.3%) children with a significant antecedent and/or HS. Five children had a significant illness or event before the onset of TLE, including perinatal hypoxic-ischemic encephalopathy in one, encephalitis in one, traumatic brain injury in two, and complex febrile seizures in one. HS was found in the patients with traumatic brain injury and complex febrile seizures in the history in addition to two children without known antecedents. Group 3 comprised 15 (50%) children with no abnormality on neuroimaging and no significant antecedents (cryptogenic TLE). CONCLUSIONS: Etiologic differences between children with new-onset TLE may have prognostic implications: children with TLE and significant antecedents/HS are expected to have the greatest risk of continued seizures and psychological problems.

Child↗

The determinants of breast cancer screening behavior: a focus group study of women in the United Arab Emirates.

PURPOSE/OBJECTIVES: To explore perceptions, knowledge, attitudes, and beliefs about breast cancer and its screening among Emirati national women in Al Ain, United Arab Emirates. DESIGN: A qualitative study using focus group methods. SETTING: Primary healthcare centers and a community-based women's association in the United Arab Emirates. SAMPLE: 41 women, aged 25-45 years. METHODS: Four 90-minute focus group discussions exploring perceptions, knowledge, attitudes, beliefs, and practices regarding breast cancer were audiotaped, transcribed, translated, and analyzed. MAIN RESEARCH VARIABLES: Social and cultural themes related to breast cancer and its screening. FINDINGS: Focus group methodology worked well in this setting. The women's perceptions, knowledge, attitudes, and beliefs regarding cancer and screening, together with aspects of the healthcare system and social milieu, appeared to strongly influence the women's preventive practices. Some of these factors had an encouraging effect on the women's practices, and others had a deterring effect. The encouraging factors included feelings of susceptibility, high levels of knowledge in some women, attitudes and beliefs about personal responsibility for health, and a supportive social milieu. Deterring factors included anxiety and fear leading to denial; lack of knowledge about cancer and the screening program; fear, embarrassment, and mistrust of health care; and belief in predestination. CONCLUSIONS: Health planners and healthcare providers must capitalize on encouraging factors and minimize deterring factors to optimize breast cancer screening practices among these women. IMPLICATIONS FOR NURSING: Identifying and accounting for the factors that encourage or deter women in their breast cancer screening practices will help to optimize screening programs.

Adult↗

Folic acid awareness and intake survey in the United Arab Emirates.

OBJECTIVE: The aim of this study was to determine the level of knowledge and use of periconceptional folic acid supplementation in a sample of postpartum women recruited from three hospitals. DESIGN: Cross-sectional survey in which a structured questionnaire was used in a face-to-face encounter between the subject and a trained nurse. SETTINGS: Two teaching hospitals associated with Faculty of Medicine and Health Sciences and one private hospital. SUBJECTS: Postpartum women in the three hospitals were recruited during a 40-day period in November 1999. Women who did not agree to participate, had complicated labor, delivered babies with congenital malformations, or were too exhausted or difficult to examine, were excluded. RESULTS: Univariate analyses showed that overall 46.4% of the respondents had heard about folic acid and only 8.7% knew that it prevented birth defects. 45.5% of respondents took folic acid in the first trimester. The percentage of women who had ever heard about folic acid was higher in those with higher education, and those who were not UAE nationals. Use of folic acid was associated with non-UAE nationality. CONCLUSION: Awareness of the value of periconceptional folic acid was very low and use of folic acid was less prevalent among women of UAE nationality.

Adult↗