[Early pseudopuberty revealing juvenile granulosa tumor of the ovary].
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Biomedical subjects
Publications and source records attributed to Abdellatif Nouri.
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We have conducted a retrospective study about 8 infants having CLE and who were hospitalised for 11 years in the Pediatric department of Sfax university hospital (1989-1999). The average age of these patients having revealing symptoms ranges from birth to 8 months, with an average age of 2 months and 3 weeks. During the neo-natal period (< 1 month), the disease was found among 35.5% of the patients. The discovery circumstances are represented by a permanent dyspnea in 4 cases, repetitive bronchopneumopathies with paroxystic dyspnea in 2 cases, a prolonged bronchopneumopathy in one case and a whooping cough in one case. The pre-operatory diagnosis was suspected on the chest-radiography in all cases and on the chest scanner in 7 cases. All patients have undergone a surgical treatment. The anatomy-pathological exam has confirmed the diagnosis in all cases. The immediate post-operatory results were simple in all the 8 cases and the long-term evolution has shown minor respiratory and orthopedic defects only in one patient aged 8 at present. The CLE is a lung-malformation often responsible for serious respiratory problems. The symptomatic forms should be operated very early because the ulterior "prognosis" depends on the patient's age at the moment of the surgery.
Nephroblastomatosis is a rare disease, considered to be a precursor of Wilms tumour. When it is isolated, recommended treatment consists of chemotherapy followed by surveillance. In the presence of associated Wilms tumour, treatment consists of preoperative chemotherapy followed by partial nephrectomy (when possible), followed by postoperative chemotherapy and surveillance.
Mesoblastic nephroma is a rare renal tumour mainly observed in neonates and young infants. The authors report a case in a 5-day-old new-born infant presenting with an isolated abdominal mass occupying the left hypochondrium and flank. Ultrasonography demonstrated a 4 cm heterogeneous mass in the lower pole and middle of the left kidney. CT showed an intensely contrast-enhanced heterogeneous mass. The patient was treated by left radical nephrectomy with an uneventful postoperative course. The outcome was favourable without recurrence with a follow-up of one year. Mesoblastic nephroma is considered to be a benign tumour. The diagnosis is suggested by clinical, ultrasonographic and CT findings. Treatment is based on radical nephrectomy. In the light of this case, the authors discuss the clinical, radiological and therapeutic aspects of this tumour.
Transverse ectopic testis (TET) is a rare form of ectopic testis. The authors report the case of a 2-month-old infant presenting with right inguinoscrotal hernia and ectopic left testis with an impalpable testis. Opening of the hernia sac revealed two testes with two distally fused vasa deferentes. The contralateral testis was easily descended by translocation through the other inguinal canal. A favourable result was obtained with two testes situated in a normal position. In the light of this case, the authors emphasize the clinical and therapeutic features of this anomaly.