Biomedical subjects

A el Nawar

Publications and source records attributed to A el Nawar.

4 recordsLinked to original sources

PubMedDate not supplied

Percutaneous endoscopic gastrostomy.

From March 87 to March 92, fifty eight patients were referred to our department for percutaneous endoscopic gastrostomy (PEG). The modality of the feeding tube insertion is described. The most common indications for placement were neurologic disorders in 62% of the cases (n = 36) and malignant diseases in 32% (n = 19). The success rate of the technique was 98.3% (n = 57). No procedure-related mortality was observed. A low rate of major complication (1.7%) and minor complication (10.5%) was noted. Feeding tubes were removed in 21% of patients (n = 12); none of them with malignant disease. Survival curve analysis demonstrated that 50% of patients died within 3 months of PEG placement. Such results raise questions about the selection of patients undergoing PEG. Our experience of patients undergoing PEG. Our experience suggests that PEG is easy and safe, even in debilitated patients, having an acceptable life expectancy.

Central Nervous System Diseases↗

PubMedDate not supplied

[Enteroscopy: methods and results].

Recent advances in the instrumentation and techniques of enteroscopy now permit examination of the small bowel. This report is on the use of a prototypic small bowel enteroscopy to investigate patients with gastrointestinal bleeding of obscure origin. We used the sonde-type enteroscope (Olympus Corp.) that migrates distally responding to peristaltic activity. This instrument has neither tip deflection controls nor interventional capability. Small bowel enteroscopy was performed in 17 patients. Arteriovenous malformations were visualized in 5 patients but three of them suffered from Rendu-Osler disease. Small bowel enteroscopy can be useful in the evaluation of patients with gastrointestinal bleeding of obscure origin. However, patients must be well selected on basis of negative routine examinations because this method is time-consuming.

Adult↗

PubMedDate not supplied

Increased transaminases in psychiatry: a case report.

We report the case of a patient admitted to the hospital with psychiatric troubles. Soon after admission, he presented severe hepatitis of unknown origin. Careful review of the charts, transvenous liver biopsy, right heart and hepatic pressure measurements, negative toxicologic and viral screenings were highly suggestive of hypoxic hepatitis. Indeed, the patient had previously been treated for a decompensated cardiomyopathy and medications stopped prior to the current admission. Without clear clinical evidence of heart failure he presented a brief malaise two days before the increase in liver enzymes. Holter heart recording showed afterwards bouts of ventricular tachycardia. Treatment with Dobutamine and antiarrythmics led to a rapid decrease of transaminase levels and recovery in liver function. Unfortunately, he died three weeks later from his cardiomyopathy. This case illustrates the need for cardiovascular work-up in the context of hepatitis from unknown origin.

Adrenergic beta-Agonists↗

PubMedDate not supplied

Treatment with terlipressin as a bridge to liver transplantation in a patient with hepatorenal syndrome.

Hepatorenal syndrome is a rapidly lethal complication of cirrhosis. The present case provides further evidence of the efficacy of terlipressin in this context even with concomitant treatment with propranolol. A 56 year old male with HBV related cirrhosis developed renal failure characteristic of hepatorenal syndrome. He was also taking propranolol for primary prophylaxis of variceal bleeding. Terlipressin 6 mg/day was administered during haemodialysis and after 1 week plasma creatinine dropped from 6.2 to 2.8 mg%. Daily urinary volume, plasma sodium and natriuresis dramatically increased during the treatment. Discontinuation of the treatment led to a rapid relapse of renal failure (plasma creatinine from 1.8 to 2.2 mg%) and the drug was readministered until a successful liver transplantation could be performed 1 month after the beginning of the treatment. The patient has now a near normal renal function 3 months after transplantation.

Antihypertensive Agents↗