Search PubMed⌕ Search

Biomedical subjects

A de C Azevedo

Publications and source records attributed to A de C Azevedo.

At least 19 recordsLinked to original sources
PubMed1993

[Association between carotid and coronary atherosclerosis. Evaluation of carotid arteries by echography with Doppler].

PURPOSE: To evaluate the association between carotid and coronary atherosclerosis and other conditions related to the prevalence of carotid disease. METHODS: Duplex scanning of carotid arteries was performed in 130 patients (70 males and 60 females), with ages between 26 and 89 years-old. Accordingly to the presence of ischemic heart disease, they were divided in 3 groups: I) with proved ischemic heart disease; II) with low probability of disease and III) with high probability of disease. The carotid atherosclerosis was classified as absent (normal result), mild (obstruction below 30%), moderate (30-49%), moderate/severe (50-74%), severe (> 75%), and total occlusion (abnormal results) by Doppler criteria. RESULTS: Normal carotids were found in 44 (33.9%), mild atherosclerosis in 68 (52.3%), moderate in 7 (5.4%), moderate/severe in 5 (3.8%), severe in 5 (3.8%) and total occlusion in 1 (0.8%) of the 130 patients. The prevalence of the disease increased with age (31.2% in patients until 54 years-old, 66.3% in those with age between 55 and 76 years-old, and 88% in those with 77 years-old or more), and it was higher in males than females (75.7% x 55%). All the differences were of statistical significance. In the 48 patients of group I, 41 (85.4%) had abnormal carotids (26 mild, 6 moderate, 3 moderate/severe, 5 severe, and 1 total), whereas in the 64 patients of group II, 27 (42.2%) were abnormals (24 mild, 1 moderate, and 2 moderate/severe), significant difference with p < 0.001. This significant difference persisted when the groups II and III were joined, and 45 (54.9%) of 82 patients had abnormal carotids. All the patients with severe obstruction of carotid arteries (6 patients) had severe coronary obstruction. CONCLUSION: The prevalence of carotid atherosclerosis was high, in 66.2% of the patients. It increased with age, and it was higher in males than females. There was statistically significant association between carotid and coronary atherosclerosis, and the presence of severe carotid obstruction was related to presence of severe coronary obstruction.

Adult↗
PubMed1991

[Silent myocardial ischemia: its increase with aging].

PURPOSE: To evaluate whether the number and duration of the episodes of silent myocardial ischemia increase with aging of patients. METHODS: A Holter monitoring, with CardioData equipment, was made in 1,300 patients and 330 with proven significant coronary obstructions were selected for this study. The anti-anginal medication was maintained during the 24 or 48 hours of Holter recording. The patients were arbitrarily divided into four groups according to age less than 50 years, 50 to 59 years, 60 to 69 years and greater than or equal to 70 years old. The statistical analysis was made with two models, the model of logistic regression and the Poisson model. RESULTS: Myocardia ischemia was detected in 72 patients (21.8%), 55 (76%) had only silent episodes, 6 (9%) had only anginal ischemia and 11 patients (155) had both silent and anginal ischemia. There was a progressive increase in the number and duration of the episodes of myocardial ischemia with aging. The proportion of patients with episodes of myocardial ischemia in the 4 age groups was 12.12%, 19.75%, 22.25% and 31.48% and the duration of the episodes of ischemia per patient 37, 37.5, 50.8 and 85.1 minutes, respectively. Statistical analysis showed a significant increase with aging in number and duration of the episodes. CONCLUSIONS: Myocardial ischemia is still present in asymptomatic patients during anti-anginal treatment and the ischemia is mainly silent. There is a progressive increase with aging in number and duration of the episodes of ischemia.

Age Factors↗
PubMed1991

[Nyctohemeral recording of blood pressure and heart rate. Preliminary study].

PURPOSE: A preliminary report is presented of the 24 hour monitoring of blood pressure (BP) and heart rate (HR). PATIENTS AND METHODS: Ten normotensive persons, 5 of each sex with age between 30 and 65 (mean age 41.4) years. The recorder model TM 2420 made by A & D Co. of Japan was used. It has a blood pressure cuff and a recorder that utilized the Korotkoff sounds. It is possible to register the BP with intervals of 1 up to 60 minutes with a circadian division of up to 4 separate periods. A compact analyzer-computer with a printer processing unit prints each recording of PB and HR, the mean value and standard deviation of each period and of the total period of 24 hours. RESULTS: During day time the systolic BP ranged from 96 to 140 mmHg (mean 118.7 +/- 11 mmHg) and the diastolic BP ranged from 67 to 90 mmHg (mean 75.2 +/- mmHg). In the period from 0 to 6 hours AM the systolic BP ranged from 81 to 115 mmHg (mean 102 +/- 13.7 mmHg) and the diastolic BP ranged from 63 to 86 mmHg (mean 67.2 +/- 9.3 mmHg). The mean HR ranged from 75 to 94 beats per minute (mean 84.3 +/- 31). CONCLUSION: This lowering of BP during the night correlates with the variations of plasma nor-epinephrine. The main advantages of the circadian monitoring of blood pressure are: 1) to identify the false diagnosis of hypertension based on casual readings; 2) the significant correlation found between prognosis, end-organ-lesion and the pressure load (proportion of BP above normally) or the mean value of BP, while end-organ-lesion and prognosis correlates poorly with casual blood pressure.

Adult↗
PubMed1989

[Silent myocardial ischemia. Experience with ambulatory electrocardiographic monitoring].

A 24-hour recording of ambulatory EKG (Holter) was obtained in 159 patients with coronary disease: previous myocardial infarction (n = 76), myocardial revascularization (n = 66), severe obstruction during cine-coronarography (n = 13) or during coronary angioplasty (n = 4). Prophylactic anti-anginal drugs were maintained during the Holter and, despite the medication, transitory episodes of myocardial ischemia (MI) were recorded in 51 patients (32%), either with angina (AMI) or silent (SMI), isolated SMI was recorded in 44 patients (86%), 6 subjects had both SMI (16 episodes) and AMI (12 episodes) and one patient had only one episode of AMI. There was a total of 119 episodes of MI, 106 of SMI (89.1%) and 13 AMI (10.9%). The total duration of the episodes of SMI per patient varied from 1 min to 235 min and the IMS maximal duration was 221 min. In the six cases with both SMI and AMI, the total duration of SMI was 461 min and AMI was 306 min. The circadian distribution of the episodes of SMI was: from 12:00 to 18:00-31.4%, 18:00 to 24:00-27.6%, 0:00 to 6:00-7.7% and 6:00 to 12:00-33.3%. The SMI activity was recorded in 89 episodes-23.6% during sleep, 22.4% at rest, 46% during physical activity and 8% during other activities. The mean ST segment depression during SMI (n = 106) was of -2.25 mm and during AMI (n = 13) was of -3.25 mm.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗