Search PubMed⌕ Search

Biomedical subjects

A Z Gyory

Publications and source records attributed to A Z Gyory.

27 records · Page 2Linked to original sources
PubMed1984

Role of renin and aldosterone in establishment of electrolyte balance in very low birthweight neonates.

Urine sodium, potassium and chloride excretion, plasma renin activity (PRA) and urine aldosterone excretion (UAE) were measured in seven very low birthweight (VLBW) infants during the first 6 weeks after birth. Hyponatraemia was most common, and major changes in urine electrolyte excretion occurred, during the first 2 weeks. These changes in urine electrolyte excretion appeared to relate to improvement in distal tubular function. PRA did not correlate with urine excretion of either aldosterone or electrolytes. However, UAE correlated significantly with fractional sodium-potassium exchange in the distal tubule in a non-linear fashion (P less than 0.001) which suggested a threshold of aldosterone responsiveness between 70 and 100 nmol/24 h per 1.73 m2 UAE. We conclude that in VLBW infants the distal tubule can respond to aldosterone during the first 2-3 weeks, but that the threshold for responsiveness appears to be higher than it is in fullterm infants.

Aldosterone↗
PubMed1981

A prospective study of serum complement (C3 and C4) levels in normal human pregnancy: effect of the development of pregnancy-associated hypertension.

Serum levels of complement components (C3 and C4) were measured serially in 173 initially normotensive pregnant women and the results compared with those obtained in 32 nonpregnant women of similar ages. There was significant elevation of serum levels of both C3 and C4 during gestation. Pregnancy-associated hypertension developed in the third trimester in 26 pregnant women but they had the-same degree of elevation of serum C3 and C4 levels as did the 147 pregnant women who remained normotensive throughout their pregnancy. Measurements of serum C3 and C4 levels and therefore of no value in predicting the development of pregnancy-associated hypertension.

Adolescent↗
PubMed1980

Cardiac and haemodynamic measurements in hypertensive pregnancy.

1. Haemodynamic and left ventricular variables were determined by M-mode echocardiography in 21 normotensive and 36 hypertensive patients during the last trimester of pregnancy. 2. Blood pressure of hypertensive patients was lowered by bed rest only, or by oxprenolol or methyldopa, but remained elevated. 3. Cardiac output was raised in the last trimester of pregnancy in both normotensive and hypertensive patients. 4. Left ventricular mass was increased in normal pregnancy, but displayed an exaggerated increase in hypertensive patients. 5. Total peripheral resistance was inappropriately elevated in hypertensive pregnancy, except in the oxprenolol-treated group. 6. There ws no reduction in heart rate or cardiac output in the group treated with beta-adrenoreceptor blocking agents. These factors, in combination with normal peripheral resistance, may contribute to the improvement in foetal outcome described in maternal hypertension of pregnancy treated with oxprenolol.

Adult↗
PubMed1978

Microscopic examination of urine.

Two methods of expressing microscopically observed leucocytes, erythrocytes, and casts in urine, both with centrifugation, one quantitatively (per ml) and the other per high-power field (H.P.F.), were compared for reliability in predicting renal functional abnormalities. In a series of 88 duplicate urines, abnormal numbers of casts or white or red blood-cells were detected by the quantitative method im 74% of patients with abnormal renal function but in only 36% by the N.P.F. method. The hourly excretion-rate of leucocytes over 3 1/2 h correlated very closely with the leucocyte concentration (cells/ml) measured by the quantitative method, so that a timed collection of urine was unnecessary. Unless findings from urinary microscopy can be relied upon, through adoption of a quantitative method, abnormal urines may be judged normal and some cases of glomerulonephritis may be falsely designated "clinically silent".

Blood Cell Count↗
PubMedDate not supplied

Haemodynamics of hypertension in pregnancy assessed by M-mode echocardiography.

1. Echocardiographic haemodynamic and left ventricular parameters were determined in twenty-one normontensives and thirty-six hypertensives during the last trimester of pregnancy. 2. Equivalent blood pressure control was obtained in hypertensives with bet rest only, oxprenolol or methyldopa, but remained above normotensive levels. 3. Cardiac output was elevated in the last trimester of pregnancy in normotensivves and hypertensives. 4. Left ventricular mass was increased in normal pregnancy, but displayed an exaggerated increase in hypertensives. 5. Total peripheral resistance was inappropriately elevated in hypertensive pregnancy, but was normalized in the oxprenolol-treated group. 6. There was no reduction in heart rate or cardiac output in the beta-adrenoreceptor blocker-treated group. This feature, in combination with lowered peripheral resistance, may contribute to the improvement in foetal outcome observed in maternal hypertension of pregnancy treated with oxprenolol.

Adrenergic beta-Antagonists↗
PubMedDate not supplied

Capillary permeability in normal and hypertensive human pregnancy.

Capillary permeability (CP) is elevated in late normal pregnancy, when compared to postpartum values. In women with pregnancy associated hypertension (PAH), pregnancy CP levels are not different from postpartum and are less than in normal pregnancy. These changes in capillary permeability are not explained by alterations in serum albumin.

Adult↗
PubMedDate not supplied

Blood pressure responses to dietary sodium manipulation during normotensive human pregnancy.

Short-term salt loading and salt restriction in a group of normal pregnant women produced no changes in lying, sitting or standing blood pressures or heart rates. Home blood pressures showed no trend to change over the periods of altered salt intake. Although plasma volume and plasma renin activity changed with altered salt intake, there were no relationships between changes in these parameters and changes in mean arterial pressures (MAP) between the low and high salt diets. Capillary permeability and echocardiographic dimensions were unchanged by salt intake once sodium balance had been established.

Adolescent↗