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Biomedical subjects

A Yussim

Publications and source records attributed to A Yussim.

At least 73 records · Page 4Linked to original sources
PubMed1989

Suicide by related kidney donors following the recipients' death.

Two cases of suicide by related kidney donors following graft rejection and the death of the recipients are reported. It is concluded that psychiatric screening of the donor before transplantation is necessary in order to obtain information about past psychopathology, ambivalence involved in donating the kidney, psychological style, characteristic defenses and behavioral repertoire used to cope with anxiety and disappointed life circumstances. The data are necessary to assess the donor's capability of accepting a possible failure of the transplantation procedure. A psychiatric evaluation after transplantation is indicated following graft rejection and death of the recipient to assess the development of depression and suicidal potential of the related donor.

Adaptation, Psychological↗
PubMed1988

Page kidney phenomenon in kidney allograft following peritransplant lymphocele.

A case of kidney allograft dysfunction in a recipient with a prior lymphocele is described. We attribute it to a Page kidney phenomenon caused by a constrictive pericapsular fibrosis. Surgical exploration and excision of the fibrotic tissue were followed by the recovery of renal transplant function. To our knowledge, only 1 case of Page kidney in renal allograft due to peritransplant hematoma has been described in the literature.

Adult↗
PubMed1985

The use of the portal system for the transplantation of a neonate kidney graft in a child with Wilms' tumor.

A single an-encephalus neonate kidney graft was transplanted into the portal system of a 6-year-old recipient who had previously undergone removal of the right kidney and inferior vena cava because of Wilms tumor. The left kidney ceased to function shortly thereafter. The child was supported very poorly on hemodialysis, and showed repeated very high levels of cytotoxic antibodies in her serum. The first cross-negative kidney graft that was available harbored two main arteries and duplicate collecting system with two very thin ureters. These vascular anatomic and pathologic variations of both donor graft and recipient necessitated the use of the portal system for renal graft venous drainage and the aorta for the graft revascularization. The ureters that had pinpoint-like lumen were inserted together into the lumen of the native ureter stump and fixated. One year after the transplantation the serum creatinine level is 1.8 mg/dL.

Aorta↗
PubMed1985

Infections in renal transplant recipients in Israel.

A 5-year retrospective survey of infections following 258 renal transplants in 233 patients is reported from a large medical center in Israel. The most common sites of infection were the urinary tract, the surgical incision, and the lung. We recorded 157 episodes of bacteriuria, 75% during the first month following transplantation. In 24 patients, 25 episodes of bacteremia were documented, with gram-negative bacteria being the most commonly involved organism. Pneumonia was diagnosed in 36 patients and was associated with relatively high mortality. Cytomegalovirus was the most common single organism responsible for infection. Fatal rhinocerebral mucormycosis was observed in three patients and was the most common invasive fungal infection. Other serious opportunistic infections were seen only rarely. Infectious diseases were the most frequent cause of death (51.1%) among these patients.

Adolescent↗
PubMed1985

T cell subsets in renal transplanted patients defined by theophylline sensitivity and monoclonal antibodies.

Peripheral T cell subsets were determined in 26 patients after renal transplantation. Thirteen patients were undergoing acute rejection episodes at the time of blood sampling. Two methods were used for the determinations: the theophylline sensitivity test (THST) and the monoclonal antibodies method OKT8 and OKT4. In both rejecting and non-rejecting groups, the percentages of T suppressor lymphocytes (TS) was found to be higher by the OKT8 method than by the THST. Furthermore, no significant difference in TS percentages could be revealed by the OKT8 method between the two groups. However, with the THST the differences were significant with a mean value of 13.5 +/- 7.9 per cent in the rejecting group and 21 +/- 5.9 per cent in the non-rejecting group (p less than 0.01). The different results between the two methods could be attributed to the fact that by THST only TS cells are defined while the OKT8 conjugates also with cytotoxic T lymphocytes. The measuring of T helper cells (TH) revealed much higher percentages of TH in the rejecting group than in the non-rejecting group, 51 +/- 9.5 per cent mean value and 29 +/- 13 per cent mean value, respectively (p less than 0.05). The ratio OKT4+/OKT8+ was below one in the non-rejecting group and above 1.5 in the rejecting group. We concluded that the THST as well as OKT4+/OKT8+ ratio may be a helpful laboratory test to confirm a clinically suspected acute rejection episode.

Antibodies, Monoclonal↗
PubMed1985

Kidney transplantation in patients on continuous ambulatory peritoneal dialysis.

In the 45 months from April 1980 to December 1983, 137 patients received first cadaver kidney grafts. Thirty-two of the patients were on continuous ambulatory peritoneal dialysis (CAPD group) and 105 were on haemodialysis (HD group). The two groups of patients were similar in respect to pre-transplant blood transfusions, mean age, HLA-A, B, DR matching and immunosuppressive therapy. In 14 CAPD patients at least one episode of peritonitis was documented before transplantation. The actuarial graft and patient survival was 57 per cent and 84.4 per cent, respectively for the CAPD group and 55.8 per cent and 85.3 per cent in the HD group. No patient in either group had evidence of peritonitis after the transplantation. These similar results indicate that kidney transplantation in CAPD patients carries no greater risk than in patients on haemodialysis.

Adolescent↗