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Biomedical subjects

A Yazigi

Publications and source records attributed to A Yazigi.

At least 37 records · Page 2Linked to original sources

Mivacurium in an obese patient with myotonic dystrophy--a case report.

Mivacurium is a short-acting non-deplolarizing neuromuscular blocking agent. Its use in an obese patient with myotonic dystrophy undergoing laparoscopic cholecystectomy is reported. Mivacurium was used as a bolus dose of 0.07 mg. kg-1, followed by a continuous infusion at the rate of 0.003 mg. kg-1. min-1. Muscle relaxation, monitored by a train of four count, was adequate throughout the surgery. Spontaneous recovery of the neuromuscular function was obtained fifteen minutes after the end of mivacurium infusion. Neostigmine was not given. Postoperative mechanical ventilation and respiratory complications were avoided.

Anesthesia↗

[Comparative measurement of pressure in the abdominal inferior vena cava and in the superior vena cava in adults].

Abdominal inferior vena cava pressure was compared to intrathoracic central venous pressure in 30 adults admitted in an intensive care unit following coronary artery bypass grafting. Mean pressures were obtained during controlled ventilation with a positive end expiratory pressure (PEEP) of zero and 10 cmH2O respectively, and during spontaneous breathing as well. Ninety measurements were obtained. Limits of agreement between intra-abdominal and intrathoracic cava pressures were below 2.5 mmHg in all cases. In this study, inferior vena cava pressure has predicted central venous pressure in adults during both controlled and spontaneous ventilation.

Adult↗

[Coronary surgery in patients 70 years and older. Report of 70 cases].

Between January 1993 and January 1995, seventy patients over 70 years of age underwent coronary artery revascularization and were retrospectively reviewed. The anesthetic protocole, the surgical technique and the intraoperative myocardial protection were similar for all patients. Fourteen patients (19.8%) suffered major postoperative complications: stroke (3 cases), myocardial infarction (5 cases), left ventricular failure with intraaortic counter-pulsation (2 cases), gastrointestinal hemorrhage (2 cases), respiratory failure (2 cases). Thirty patients (42.6%) had minor complications with no impact on survival or hospital stay. Hospital mortality was 7.1% (5 patients) and was caused by left ventricular failure (2 cases), stroke (1 case), gastrointestinal hemorrhage (1 case), respiratory failure (1 case). Mortality was found to be correlated with preoperative renal failure, peripheral vascular disease and concomitant carotid endarterectomy. Patients remained in the cardiac surgery unit for 60 hours. The mean length of hospital stay was 8.2 days. Follow-up from 1 to 24 months revealed NYHA angina class I-II in 85% of the patients. These results are similar to other studies. We conclude that coronary artery revascularization in the elderly yields good results, with fair mortality and morbidity rates.

Aged↗

[Duplication of the vena cava].

Bilateral superior vena cava is a congenital anomaly of which the anaesthesiologist and intensivist should be aware in order to not mistake catheters placed in the left superior vena cava as being malpositioned outside of the venous circulation. These malpositions generally require catheter removal and reinsertion. This anomaly although rare is not-so-unusual. It is generally well tolerated.

Aged↗

Hemodynamic effects of pressure support ventilation following cardiac surgery.

Hemodynamic effects of pressure support ventilation (PSV) were assessed in 33 patients, after cardiac surgery. The patients, selected for their stable left ventricular and respiratory functions, underwent uncomplicated coronary artery bypass grafting. They all underwent the same anesthetic protocol, and an invasive hemodynamic monitoring. Eight to ten hours postoperatively, while all patients were fully awake, normothermic and hemodynamically stable, controlled ventilation (CV) was replaced by 3 levels of PSV (20, 10, 5 cm H2O). These levels were applied consecutively for 20 minutes each, before extubation. Hemodynamic and gas exchange data were recorded on CV, on each level of PSV, and on spontaneous breathing. The results were analyzed using ANOVA and Bonfferoni methods. No statistical significance could be noted between the five modes of ventilation as to hemodynamic parameters, arterial and mixed venous blood gases, and oxygen consumption (VO2). The only 2 parameters that reached statistical significance were central venous pressure and respiratory rate. Our study demonstrates that patients with stable cardiovascular and respiratory function can adapt to different levels of PSV without hemodynamic modifications or an increase in their VO2.

Adult↗

[Complications and outcome of implantable infusion pumps: apropos of 60 cases].

The aim of this study was to analyse the complications and the outcome in 59 patients with 60 implantable ports for cancer chemotherapy. Perioperative complications included: subcutaneous haematoma (n = 6), wrong position of the catheter tip (n = 2), accidental intravascular injection of lidocaine with adrenaline (n = 1), vagal reflex (n = 1) and pneumothorax (n = 1). Late complications included extravasation of drugs (n = 4), wound dehiscence (n = 1), spontaneous migration of the catheter tip (n = 2), venous thrombosis (n: = 2), septicaemia (n = 6), local discomfort (n = 6) and ports' obstruction (n = 15). In 11 cases, repermeabilization was possible with heparin or streptokinase. Patients were followed up to 40 months, 37% died with a patent port, 6% died with an obstructed port and 45% are still alive with a functional port. Twelve percent of the ports were removed. The lack of life-threatening complications, the high rate of satisfied patients (85%) and the long mean period of use (11 months) in this study are similar to those published in the literature and confirm the value of implantable ports for chemotherapy.

Follow-Up Studies↗

[Anaphylactic shock due to modified fluid gels: 2 case reports].

UNLABELLED: Colloid solutions can give severe anaphylactic accidents. We are reporting two cases from our department. FIRST CASE: a sixty eight years old man perfused with Plasmion solution (Gelatin plasma substitute) before spinal anesthesia, presented sudden hypotension and diffuse skin rush. Second case: a twelve years old girl, receiving a Plasmion solution to correct a hypovolemic shock in I.C.U, presented a severe bronchospasm and a worsening of the hypotension. These accidents are explained by immunologic reactions or by direct histamine release. Their incidence is between 0.01 and 0.8 percent depending on the used solution. They are prevented by an antihistaminic premedication for the gelatin plasma substitutes and by an haptenic inhibition for Dextran (polysaccharide plasma substitutes). The new colloid solutions, based on hydroxyethylstarch, seems to give much less allergic reactions.

Aged↗

[Secondary migration of a central venous catheter linked to an implantable port].

The secondary migration of the distal part of a central venous catheter with implantable port is rarely described. This study reports a case in which the distal part of a catheter with implantable port moved spontaneously, a month after its implantation in a branch of the internal jugular vein without any other complication. The discussion is about modalities, frequency and explanation mechanisms of the complications due to central catheters. The conclusion insists on systematical radiologic control of the position of implantable port with central venous access, and in case of bad working or any sign of thrombo-phlebitis.

Catheterization, Central Venous↗

[Use of implantable chemotherapy reservoirs. Experience at the Hotel-Dieu of France].

We are presenting our experience with 70 deep venous catheters for long term chemotherapy. Despite the well known complications of these procedures, the implantation of subcutaneous injection sites has facilitated the management and brought much more comfort to cancer patients. Strict measures of survey and meticulous nursing care are essential for optimal use of the injection sites.

Adolescent↗

The effect of education and written material on compliance of pediatric clients.

One hundred and fifty babies and their mothers, presenting to the Well Baby Clinic of the Pediatric Outpatient Department were studied for compliance. They were divided randomly into three groups, one serving as a control (n = 55) and two as experimental groups (n = 48 and 47). The latter were exposed to two different intervention methods; teaching and written material respectively, in addition to the routine care given to the control group. The three groups were compared in terms of compliance and improvement in knowledge. The results showed that reinforcement of the doctor's advice by a nurse, or written instructions to the patients, did not improve knowledge or compliance. Possible explanations for such results are given and suggestions for other modes of intervention are made.

Attitude to Health↗

Unilateral pulmonary oedema/atelectasis in the lateral decubitus position.

An obese male patient developed hypoxia, hyercarbia and radiological signs of pulmonary oedema/atelectasis in the dependent lung after surgery in the lateral decubitus position. This appears to have been due to ventilation-perfusion mismatch, although other factors were considered. The patient recovered following 36 hours of intermittent positive pressure ventilation of the lungs.

Humans↗

Patient compliance in a well baby clinic. Effect of two modes of intervention.

One hundred and fifty babies and their mothers, presenting to the Well Baby Clinic of the Pediatric Outpatient Department were studied for compliance. They were divided randomly into three groups, one serving as a control [n = 55] and two as experimental groups [n = 48 and n = 47 respectively]. The latter were exposed to two different intervention methods respectively, in addition to the routine care given to the control group. The three groups were compared in terms of compliance and improvement in knowledge. The results showed that reinforcement of the doctor's advice by a nurse, or written instructions to the patients, did not improve knowledge nor compliance. Possible explanations for such results are given and suggestions for other modes of intervention are made.

Adult↗