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Biomedical subjects

A Wojciechowska

Publications and source records attributed to A Wojciechowska.

18 recordsLinked to original sources
PubMed2002

Flow-injection amperometric determination of pesticides on the basis of their inhibition of immobilized acetylcholinesterases of different origin.

Determination of the organophosphorus pesticides paraoxon, chlorpyrifos oxon, and malaoxon has been performed by a method based on inhibition of acetylcholinesterase (AChE) and amperometric detection in a flow-injection system with enzymes obtained from the electric eel (eeAChE) and Drosophila melanogaster (dmAChE) and immobilized on the surface of platinum electrode within a layer of poly(vinyl alcohol) bearing styrylpyridinium groups. dmAChE is more sensitive than eeAChE to inhibition by chlorpyrifos oxon and paraoxon. The sensitivity difference was largest for chlorpyrifos oxon (detection limit approx. 17 times lower), and practically none for malaoxon. Determination of the analytes in spiked river water samples by use of the dmAChE biosensor resulted in recoveries from 50 to 90 % for chlorpyrifos oxon at levels of 20 to 40 nmol L(-1), 50 to 100 % for paraoxon at 0.6 to 0.8 micro mol L(-1), and 140 to 190 % for malaoxon at 0.6 to 1.2 micro mol L(-1).

Acetylcholinesterase↗
PubMed1992

[Micronization of phenytoin by precipitation].

Phenytoin was micronized by precipitation from its ammonia, ethanol, propanol, isopropanol and glacial acetic acid solutions. The precipitation was accomplished by either solvent evaporation, cooling of the solution or water addition into organic solvent solutions. The smallest particle size was obtained by evaporation of 20% ammonia solution.

Chemical Precipitation↗
PubMed1991

Usefulness of acoustic studies on the differential diagnostics of organic and functional dysphonia.

Phoniatric and acoustic examinations were carried out in a group of 30 patients with dysphonia, including 15 with organic type and 15 with functional type. A complex phoniatric assessment offered the possibility to differentiate between these two groups of pathological voices. This was achieved also on the basis of acoustic analysis of the voice by extracting characteristics such as: formant frequency, Fo and its range, percentage of noise in the analysed verbal text, mean and maximum values of jitter. The possibility of differential diagnosis of these two different types of dysphonia in acoustic studies was confirmed by clinical examinations. The acoustic studies presented can be regarded as a new approach to a fast and sufficiently precise method in the screening diagnostics of dysphonia conditioned by growth of the vocal fold mass.

Diagnosis, Differential↗
PubMed1989

[Paroxysmal atrial fibrillation as an integral part of sick (damaged) sinus syndrome].

In a studied group of 1727 subjects in 101 cases (of either sex) the sick sinus syndrome with MAS attacks++ was diagnosed on the basis of clinical and electrocardiographic criteria. The most frequent cause of the syndrome with paroxysmal atrial fibrillation was ischaemic heart disease. In 42 cases atrial pacing was applied measuring the time of own rhythm return after the end of pacing, and His bundle potentials were recorded. For practical reasons the patients were divided in two groups. Trials of treatment with atropine or isopropylnoradrenaline derivatives++ were undertaken in group A, and in group B antiarrhythmic++ drugs were used (beta-blockers, quinidine, isoptin etc). In group I (38 patients with striking bradycardia) a good therapeutic effect was observed after pharmacological treatment in 8 cases (21%). In group II (63 cases of the tachy-bradycardia syndrome) a good effect was observed in 11 cases (17.4%).

Adult↗
PubMedDate not supplied

[Preliminary evaluation of health behavior in obese students from a selected group of Warsaw adolescents].

The aim of this study was to assess health behaviour in obese pupils aged 11-17 years in one of the districts in Warsaw. Self-assessment about own health, appearance and possibilities was also studied. Questionnaire studies were carried out in pupils with obesity and in a control group of pupils, with normal body weight. We found the biggest deficiency of health promoting behaviour in the field of physical activity and dietary habits. Differences between the two groups of pupils were statistically significant. Significant differences were also found in self-assessment concerning physical fitness and appearance. We did not find any differences between obese and non-obese pupils in health risk behaviour: alcohol drinking, tobacco smoking, frequency of injuries and in psychosocial indicators.

Adolescent↗
PubMedDate not supplied

[Correlations between some features of social networks and treatment outcome in patients with schizophrenia three years after initial hospitalization].

There were studied correlations between some features of social networks of 56 DSM-III schizophrenic patients and "specific aims of treatment": insight, satisfaction of the treatment, compliance, motivation for the treatment and "outcome of treatment" in psychopathological and social level three years from the first admission. There were used Fallow-up Chart, Bizoń's Social Support Questionnaire, BPRS-LA scale and Social Assessment Scale (SAS). There were obtained statistically significant results concerning correlations between the type of support (concentrated, dispersed, and mixed) and the size of the extra-familiar network and the "specific aims" of treatment. This means that patients who have a mixed type of social support and a extended extra-familiar social network obtain better specific treatment aims as: motivation for treatment, co-operation in treatment, insight and a subjective satisfaction of treatment. There exists also significant correlation between some features of social network such as the range of network, the amount and localisation of support and the size of the extra-familiar network and the psychopathology level. The patients who get little support and those whose whole support is localised in family have higher level of negative symptoms measured with BPRS sub-scale. Patients of little range of the social network, including extra-familiar network show more positive symptoms three years after the first hospitalisation. There were found no correlations between the social network features and profession.

Adult↗
PubMedDate not supplied

[Social networks of schizophrenic patients three years after the first psychiatric hospitalization. Differences between a group treated in psychosocial program and patients treated in an individual treatment program].

Social networks of 54 DSM-III schizophrenic patients were studied. There are differences between social networks of patients who took part in the psychosocial program (n = 23) and social networks of patients treated in individual treatment program (n = 31). Patients treated in the psychosocial program receive significantly more social support from their social networks and there are significantly more new relationships in their networks than in the networks of patients treated in individual treatment program.

Adult↗