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Biomedical subjects

A Watson

Publications and source records attributed to A Watson.

358 records · Page 20Linked to original sources
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Computer memory.

Explore the source record for details and available documents.

Computers↗
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Connecting-up to computers.

Having established that the computer is capable of undertaking a wide range of complex processes in a short period of time, it becomes necessary to examine the range of devices which may be connected to a computer, and the methods of establishing communications between the user and the central processing unit (CPU).

Communication↗
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[Changes in the time of central neural conduction and of the amplitude of the potential N10 of the somatosensory evoked potentials in a model of subarachnoid hemorrhage in baboons].

On the ground of experiments on 6 baboons the authors tried to determined changes in the amplitude of the N10 somatosensory potential and the time of central neural conduction in relation to changes of the cerebral blood flow in subarachnoid haemorrhage. The following conclusions have been reached: the time of central neural conduction as well as the amplitude of the N10 cortical potential may serve as indicators of brain ischaemia after subarachnoid haemorrhage. The amplitude of the N10 potential seems to be an earlier indicator of ischaemia than the time of central neural conduction. The relationship of the changes in somatosensory evoked potentials and the brain blood flow is doubtless, but this relationship is not directly caused by changes in the cerebral blood flow.

Animals↗
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The introduction of basic computer technology into the HDCR and DCR syllabuses.

Recently, it was agreed by the College and the Radiographers' Board that amendments to the DCR (and HDCR) syllabus should include the basic principles of computer technology, and the purpose of this short paper is to suggest the type and level of expected knowledge. At DCR level this paper suggests what could constitute the total requirement, whereas at HDCR level it could be considered as forming a very adequate foundation. It is hoped this paper will also stimulate more expansive and informative contributions from other authors, which may be of a specific or more general interest to student and post-diplomate radiographers.

Computers↗
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Cerebrovascular transit characteristics of DyDTPA-BMA and GdDTPA-BMA on normal and ischemic cat brain.

PURPOSE: To compare the efficacy of two nonionic T2*-shortening contrast agents, DyDTPA-BMA dysprodiamide injection and GdDTPA-BMA gadodiamide injection, as perfusion-sensitive MR imaging agents in normal and acutely ischemic brain. METHODS: The magnetic susceptibility effects of intravenous injections of 0.10-0.50 mmol/kg of each contrast agent were quantified on T2-weighted spin-echo images of cat brain before and after unilateral occlusion of the middle cerebral artery by measuring signal intensity changes in the same regions-of-interest in parietal cortex. RESULTS: In normal brain, DyDTPA-BMA produced a significantly greater loss of signal intensity than equimolar doses of GdDTPA-BMA. The magnitude of the signal intensity attenuation was dosage-dependent and proportional to the square of the magnetic moments of the two contrast agents. Restoration of baseline image signal intensity was observed within 30 min after each injection. However, injection of GdDTPA-BMA also produced a delayed, persistent hyperintensity on T2-weighted images, presumably due to its underlying T1-shortening effect. Following unilateral occlusion of the middle cerebral artery, unenhanced T2-weighted images failed to show evidence of cerebral injury for 1.5-3 hours. Administration of 0.10-1.0 mmol/kg DyDTPA-BMA shortened the time for detection of perfusion deficits (residual hyperintensity) in 22 of 36 (61%) treated cats, often to within 30 min after arterial occlusion. DyDTPA-BMA enhancement also improved lesion conspicuity in 26 of 36 (72%) cases, and disclosed very small infarcts that were not visible on T2-weighted precontrast images. Perfusion deficits in areas of partial ischemia were seen more clearly on DyDTPA-BMA-enhanced images than after equimolar injections of GdDTPA-BMA. CONCLUSIONS: Magnetic susceptibility contrast-enhanced MR imaging enables detection of perfusion deficits associated with acute cerebral ischemia well in advance of conventional T2-weighted spin-echo MR imaging without contrast. DyDTPA-BMA appears to delineate regions of ischemic damage better than GdDTPA-BMA.

Animals↗
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Preparing for a tropical expedition.

This article reviews the medical preparations made for a 3 month expedition, The Northwest Patrol' which crossed remote Papua New Guinea in 1995-1996. It includes a variety of tips about some of the common medical problems encountered on tropical expeditions.

Diarrhea↗