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Biomedical subjects

A Warren

Publications and source records attributed to A Warren.

At least 73 records · Page 4Linked to original sources

Transgenic mosquitoes: a future vector control strategy?

Transgenic mosquitoes may provide a new way of dealing with the old problem of diseases transmitted by insects. Although many technical, and perhaps ethical, problems associated with the wild-release of transgenic insects have yet to be overcome, Julian Crampton and colleagues explore the potential of this technology in the continuing battle to control insect-borne disease.

Journal Article↗

An inexpensive apparatus for automatic continuous dehydration.

An apparatus is described for automatic dehydration of material using the principle of continuous dilution. Specimens may be dehydrated, in a period chosen by the operator, for as little as 30 min to as much as 16 hr (overnight). The apparatus is inexpensive both to construct and to run.

Histological Techniques↗

The distribution of native albumin and foreign albumin injected into lateral ventricles of prenatal and neonatal rat forebrains.

Several plasma proteins are found within the cells of the developing brain of many species, with a distribution pattern which changes during development, but the origin of such proteins is in dispute. The experiments described here were designed to test the hypothesis that some developing brain cells are able to take up plasma proteins. The distribution of the plasma protein albumin has been studied in the rat forebrain from the 14th day of gestation until birth. Although present within the cerebrospinal fluid and plasma from the earliest age studied, albumin was not seen within cells of the developing forebrain until day 16E or 17E. A foreign protein, sheep albumin, was injected into the ventricles at days 14E, 16E, 18E, 20E and on the day of birth. Sheep albumin can be detected in the presence of rat albumin because the antibody to sheep albumin does not cross-react with rat albumin. The sheep albumin was taken up very rapidly into cells of the ventricular zone at the later but not the earlier ages, thus mimicking the distribution of the naturally occurring rat albumin. After the foreign albumin had been left within the ventricle for several hours, some of the cells of the cortical plate also contained the protein, again mimicking the normal distribution of albumin. These findings suggest that the presence of albumin within cells of the developing rat forebrain can largely be attributed to uptake rather than synthesis.

Animals↗

The economic and social consequences of work-related musculoskeletal disorders: the Connecticut Upper-Extremity Surveillance Project (CUSP).

A population-based telephone survey was conducted in Connecticut to determine the social and economic impact of work-related musculoskeletal disorders (WRMSDs). Only 10.6% of cases had filed for workers' compensation. Respondents had spent an average of $489 annually out-of-pocket. Only 21% of individuals who had had medical visits or procedures reported having them paid for by workers' compensation. The WRMSD cases reported much higher levels of difficulty in daily tasks rated by the activities of daily living (ADL) scale, with odds ratios (ORs) ranging from 8.2 (child care) to 35.2 (bathing). The cases were significantly more likely to have moved for financial reasons (OR = 2.41), including having lost a home (OR = 3.44). The cases were also significantly more likely to have lost a car due to finances (OR = 2.45), more likely to have been divorced (OR = 1.91), and less likely to have been promoted (OR = 0.45). The study supports significant externalization of costs for WRMSD out of the workers' compensation system and a substantial social and economic impact on workers.

Activities of Daily Living↗