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Biomedical subjects

A Wallace

Publications and source records attributed to A Wallace.

At least 127 records · Page 7Linked to original sources

Avian tuberculosis.

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Aminosalicylic Acids↗

Day-night periodicity of exudation in detopped tobacco.

Exudate was collected periodically from the root systems of detopped tobacco plants. Volume, cations, and (42)K or (86)Rb transfer were measured. According to measurements of K by (42)K and by the flame photometer, when concentrations of KCl and KNO(3) were lower than 10(-2)m, the K in the exudate came mostly from a pool in the plant rather than from the external solution. With higher external KNO(3) solutions, within a few hours nearly all of the K in the exudate came directly from the external solutions. Studies with (86)Rb lead to the same conclusion. In contrast the maximum proportion of K in the exudate that came from KCl in the external solution was reached usually in many hours after detopping and amounted to from 50 to 75%. The higher the external concentration the faster it was reached. These data for KCl are indicative of the (42)K passing through a K pool in the root cells. K and Rb from high concentrations of KNO(3) and RbNO(3), however, may not pass through such a pool. The addition of 10(-2)m KNO(3) into the external solution during exudation essentially eliminated the effect of periodicity at least for a period of time and under the conditions of the experiments. Hydrochloric acid, mercuric chloride, anaerobiosis, and 2,4-dinitrophenol had the same effect and each resulted in a massive final exudation that usually persisted for 1 to 3 days before stopping. These results all lead to a hypothesis that periodicity is regulated at the tonoplast.

Journal Article↗

Day-night Differences in the Accumulation and Translocation of Ions by Tobacco Plants.

More K(42), Rb(86), and Br(82) was accumulated by intact tobacco plants and root systems from detopped plants during the night than during the day when studies for both periods were made in dark rooms controlled at 18 degrees . More, however, was translocated to shoots during the day than during the night in intact plants. This latter effect parallels the periodicity of exudation in root systems from detopped plants.

Journal Article↗

Tc45, a dimorphic Trypanosoma cruzi immunogen with variable chromosomal localization, is calreticulin.

We demonstrate that Tc45, a polypeptide described as an immunogenetically restricted Trypanosoma cruzi antigen in mice, is calreticulin, a dimorphic molecule encoded by genes with variable chromosomal distribution. Previously we showed that IgG from A.SW (H2s) mice immunized with T. cruzi trypomastigotes or epimastigotes and sera from infected humans recognize Tc45, a 45 kD parasite polypeptide. Herein we describe the cloning, sequencing, and expression of the Tc45 gene. A 98% homology in the deduced amino acid sequence was found with a T. cruzi calreticulin-like molecule and 41% with Leishmania donovani and human calreticulin. In the T. cruzi CL Brener clone and in the Tulahuén strain, the gene is located in two and four chromosomes, respectively. Calreticulin was detected in several T. cruzi clones, in the Tulahuén strain, and in T. rangeli, displaying alternative 43 and 46 kD forms.

Amino Acid Sequence↗

Accidents to patients in hospital: a comparative study.

A comparative study of 50 reported accident patients (cases) and 50 non-accident patients (controls) was carried out in 10 wards in a large, acute hospital, using primary and secondary data from patients, nurses and records. Folstein's Mini-Mental State test was used to measure the mental status of patients. The mental status of the controls was significantly better than that of the cases. Nurses' responses indicated that significantly more accident patients were incontinent of urine than non-accident patients. There were also indications from patients of three additional unreported accidents. Further study was needed to estimate, more closely, the frequency of unreported patient accidents. This is the second paper in a series of three. The first appeared in Nursing Times on August 17, and the final one will be published on September 28, along with implications for practice and recommendations.

Accidents↗

Unreported accidents to patients in hospital.

A study to discover the incidence of unreported patient accidents was carried out in 10 wards in a large acute hospital. There were three separate survey days, 10 weeks apart, and sources of data included patients, records and accident report books. The 574 patients who participated in the study had sustained, during their stay in hospital, 75 accidents. Of these 49 (65%) were reported (documented on an accident report form) and 26 (35%) were unreported. Multiple unreported accidents to three patients accounted for 14 of the unreported accidents. Patient responses suggested that staff knew about the unreported accidents in the majority of cases. Conclusions and recommendations from this, and the two preceding studies include improved maintenance, increased awareness of patients' views and radical change to the present reporting procedure, as ways of improving patient accident data, patient safety and care.

Accidents↗