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Biomedical subjects

A W Hall

Publications and source records attributed to A W Hall.

38 records · Page 3Linked to original sources
PubMed1975

The effects of premedication drugs on the lower oesophageal high pressure zone and reflux status of rhesus monkeys and man.

Thirty-five human volunteers and eight Rhesus monkeys were studied with standard gastrooesophageal manometric techniqes and their reflux status was evaluated witha pH probe placed in the lower oesophagus. morphine sulphate, pethidine hydrochloride, or idazepam was given intravenously until drowsiness was induced. The manometric and pH studies were repeated. All three drugs decreased the lower oesophageal high pressure zone and increased the probability of relux in both monkeys and man. Thes findings are relevant in the preparation of patients for surgery since gastrooesophageal reflux and pulmonary aspiration may be a problen in the pre-and postoperative phases.

Animals↗
PubMed1975

Treatment of obstructing cancer of the colon and rectum.

A review was made of 128 patients who had obstructing cancer of the colon and rectum. About one-third of the patients had metastatic disease at the time of presentation. Primary resection carried an initial higher mortality rate than staged resection, but at one year and three years, no statistical difference can be found between the two procedures. There are high morbidity and mortality rates with all forms of treatment. A controlled comparative trial of primary and staged resection is recommended in the treatment of obstructing cancer of the colon and rectum.

Adult↗