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Biomedical subjects

A W Frank

Publications and source records attributed to A W Frank.

7 recordsLinked to original sources
PubMed2004

Ethics as process and practice.

The noun form of ethics suggests something substantive; this substance is located in both offices of institutionalized experts and a body of canonical solutions to recognizable troubles. The present article recommends thinking of ethics not as substance but as a process of lives and decisions affecting each other over time. No single decision stands alone and no single patient can be considered as a stand-alone entity. Examples include how people struggle with choices they should not have to make, how decisions at one time are affected by earlier decisions that are not considered within the purview of ethics, and how to deal with conflicts of legitimate interests. When institutional ethics becomes a prescribed activity, the goal of being ethical is easily forgotten.

Decision Making↗
PubMed2001

Can we research suffering?

Illness troubles us because it is an occasion of suffering, but research on illness has difficulty conceptualizing suffering--and naturally so because suffering is not a concept but a lived reality that resists articulation. Based on the work of Dorothy Smith, the author argues that the rhetoric of social science inadvertently increases suffering because it attempts to organize local experience within extralocal categories. He concludes with suggestions for changing research practices.

Humans↗
PubMed2000

The standpoint of storyteller.

The legitimacy of an interest in illness narratives that is therapeutic, emancipatory, and pre-occupied with ethics is defended in response to Atkinson's critique of this interest as a blind alley. The value of storytelling as complementary to story analysis is argued, and the importance of recognizing one's own standpoint is emphasized. The conclusion considers how qualitative methods can inform changing relationships between illness, health, medicine, and culture.

Anecdotes as Topic↗
PubMed1994

Interrupted stories, interrupted lives.

In attempting to manage their practices efficiently, doctors may not allow seriously ill patients enough time to sort out their feelings and raise important questions. What is at stake here is not information about prognosis and treatments but the very survival of the soul.

Attitude to Death↗
PubMed1984

Synthesis and properties of N-, O-, and S-phospho derivatives of amino acids, peptides, and proteins.

The literature on chemical (i.e., nonenzymic) phosphorylation of amino acids, peptides, and proteins is reviewed through 1982. The review covers synthetic methods, chemical reactions, and physical properties, with emphasis on the techniques used for separation and characterization of the products. Synthetic methods are classified by reagent rather than product, and are illustrated by experimental procedures for the most important methods. Chemical reactions are classified into four groups depending on whether the reaction site is the phospho group, the amino group, the carboxyl group, or in the case of serine the hydroxyl group. Physical data are given for all of the known N-, O-, and S-phospho derivatives of the amino acids, peptides, and proteins, within certain limitations, and are discussed in detail in the section on physical properties. Emphasis is given to the techniques used for separation of the products, such as chromatography and electrophoresis, and for characterization of the products, particularly spectroscopy. Medical and other uses of the products are mentioned.

Aldehydes↗