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Biomedical subjects

A Viste

Publications and source records attributed to A Viste.

68 records · Page 4Linked to original sources
PubMed1986

Risk of carcinoma following gastric operations for benign disease. A historical cohort study of 3470 patients.

The risk of stomach cancer was analysed in a cohort of 3470 patients who had had gastric surgery for benign disease between 1900 and 1969. In 87 patients (2.2%) stomach-stump cancer was diagnosed in the follow-up period 1970-84. By comparison with the total incidence of stomach cancer in the same region during the same time period, the observed versus expected ratio in the post-surgery group was 2.1 (p less than 0.001) and did not differ between men and women. At 5-10 years postoperative the risk of cancer was no different from that in the total population, whereas after 40-45 years it was 7.3-fold higher. The risk was unrelated to primary diagnosis or type of operation.

Adult↗
PubMed1986

The prognostic value of Laurén's histopathological classification system and ABO blood groups in patients with stomach carcinoma.

The prognostic value of Laurén's histopathological classification system and the ABO blood group system has been studied in 275 patients with cancer of the stomach. The study disclosed a higher rate of tumours of intestinal type in females aged 70 years or more compared with those under 70 years, but no such relation for males. We found no relation between histopathological classification and blood groups. For patients with blood group A the 5-year survival was 17.5%, compared to 8.4% for blood group O (P less than 0.05). Survival for patients with intestinal and diffuse tumours was 17.7% and 4.8% respectively (P less than 0.01). A multivariate analysis showed that the histopathological classification system, independently, was an important factor with respect to survival (all other factors constant). Blood group might also be of importance as a prognostic factor, but further studies are necessary to confirm this.

ABO Blood-Group System↗
PubMed1985

Stomach cancer: major trends in incidence during introduction of gastroscopy service in Norway.

The age-adjusted incidence of stomach cancer has been studied during the introduction of gastroscopy service in Norway. The incidence showed an annual decrease of 3.5% for both sexes. More cases were classified within anatomic subsites. For men there was a decreasing incidence for cancers located in the antrum, for extensive tumours and for not otherwise specified (NOS) disease. No significant changes were found for cancer of the body or the cardia/fundus. In women a decrease in incidence was noted for the NOS subgroup, an increase was seen for tumours of the gastric body, and no significant changes were found for antral cancers or for tumours of the cardia/fundus. A marked increase in incidence was noted for gastric stump cancers for both sexes. During this period a shift in staging towards less advanced disease occurred. In conclusion, the increased diagnostic accuracy and the shift in staging of the disease may suggest that the introduction of gastroscopy service has been effective.

Adult↗
PubMed1984

Cancer of the stomach--is a follow-up program of any importance for the patient?

The clinical course as well as the yield and therapeutic consequences of a strict follow-up program for 206 consecutively treated patients with cancer of the stomach were studied. Median survival was 6 months, varying from 36 months in patients with localized disease to 4 months in patients with distant metastases. Survival after a curative operation was 21 months (median); after a palliative operation survival was 3 months. The 5-year survival was 13%. During follow-up recurrence was detected in 19 out of 83 patients primarily resected for cure. Ten patients had a relaparotomy, and all had non-resectable disease. Recurrence occurred early, and usually within 9 months. Patients primarily operated on for palliation or found inoperable needed further palliative treatment 4 months post-operatively (median). In 27 patients the follow-up included gastroscopy, but recurrent disease was not diagnosed in any asymptomatic patients. We conclude that a regular follow-up program will be of minor importance in prolonging survival for patients with cancer of the stomach until effective cytotoxic regimens have been developed.

Adult↗
PubMedDate not supplied

The survival benefit of resection in patients with advanced stomach cancer: the Norwegian multicenter experience. Norwegian Stomach Cancer Trial.

Five hundred three of 1,165 patients with stomach cancer included in a national multicenter study received noncurative treatment. This study elucidates whether a palliative resection offered any survival advantage compared to nonresectional treatment. One hundred eighty-two (36%) of 503 patients had gastric resection (including total gastrectomy in 64 patients), 70 (14%) had a bypass procedure, and an exploratory laparotomy was carried out in 156 (31%). Seventy-eight patients (16%) were not subjected to surgery. Resection carried the same postoperative mortality rate as a nonresectional procedure (13% versus 12%). Univariate survival analysis demonstrated that median survival and 1- and 2-year survival rates were significantly higher in resected patients; however, as basic patient characteristics (age, stage, etc.) differed between the 2 main treatment groups, survival and factors affecting survival were analyzed using the Cox proportional hazards model. Given similar age and preoperative weight loss, resection doubled median survival both for stage III disease (9 versus 4.5 mo) and for stage IV disease (6 versus 3 mo) compared to nonresection or no operation. In conclusion, resection seems justified in patients with advanced stomach cancer since a survival benefit is documented.

Gastrectomy↗
PubMedDate not supplied

Cholecystectomy improves long-term success after endoscopic treatment of CBD stones.

BACKGROUND/AIMS: The aim was to study prospectively primary endoscopic treatment of CBD stones and further the long-term need for renewed gallstone disease interventions, defined as short- and long-term outcome. METHODOLOGY: Seven years prospective follow-up of 101 consecutive patients with CBD stones who underwent endoscopic treatment with the intent of primarily achieving duct clearance. RESULTS: Many patients underwent several endoscopy sessions before stone clearance was completed in 83%. Eleven patients were treated surgically, 2 patients received a permanent stent, and the remaining 3 became stone free with other means. Complications occurred in 47 patients. During follow-up, 31 patients were readmitted for gallstone disease and 15 of these had recurrent CBD stones. Ten percent (8/78) of patients with the gallbladder in situ had acute cholecystitis during follow-up and late cholecystectomy was carried out in 22%. Risk factors for new gallstone disease were an in situ gallbladder containing stones and previous episodes of CBD stones. CONCLUSIONS: A goal of complete CBD stone clearance with ERC and ES proved to be relatively resource consuming. Subsequent cholecystectomy after duct clearance for CBD should be advised when the gallbladder lodges gallstones, especially in younger patients. Recurrent CBD stones were not influenced by cholecystectomy.

Adult↗
PubMedDate not supplied

Cancer of the stomach: are curative resections of any importance with respect to postoperative survival in patients with locoregional disease?

Ninety-seven patients operated on for cancer of the stomach with locoregional spread, i.e. invasion of adjacent tissue and/or lymph node metastases, have been studied in order to evaluate whether the surgeon's intraoperative assessment of "curative resection" was of any significance with respect to postoperative survival. Survival was not significantly different in patients who had undergone curative resection as compared with those who underwent palliative resection. Patients with unresectable disease had a significantly reduced survival rate compared with the other two groups. We conclude that resection should be performed if at all possible in patients with locoregional disease as resection seems to be effective in prolonging survival. On the other hand, whether the resection is though to be curative or palliative seems to be of less importance with respect to postoperative survival.

Adult↗