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Biomedical subjects

A Visot

Publications and source records attributed to A Visot.

49 records · Page 3Linked to original sources
PubMedDate not supplied

[Clinical use of nitroglycerin as an hypotensive agent during general anesthesia (author's transl)].

Nitroglycerine has a direct vasodilating action on both venous and arterial smooth muscle fibers. On account of this, it has been used as hypotensive agent, in aqueous solution, on 22 surgical patients, 10 of them in neurosurgery. The total doses used were 0.76 +/- 0.12 mg/kg during 94 +/- 30 minutes (rate = 8.1 microgram/kg/min). Nitroglycerine induces a rapid onset of hypotension (3 to 4 min), spontaneously reversible in 27 +/- 8 minutes after the arrest of the infusion. The mean drop in mean arterial blood pressure achieved has been 34 p. cent. It is accompanied by a 67 +/- 9 p. cent fall of filling pressures and a fall 13 +/- 4 p. cent of cardiac index, without modification of the heart rate. Tachyphylaxis was noted 15 +/- 6 minutes following nitroglycerine infusion at rate lower than 2 microgram/kg/min, but not when the rate was above 10 microgram/kg/min. Therefore, if the drug is used to achieve controlled hypotension, high doses are necessary. No signs of toxicity were noted. In 4 cases, other hypotensive agents had been used to bring the mean arterial blood pressure below 50 Torr, which could not be achieved with nitroglycerine alone.

Adolescent↗
PubMedDate not supplied

[Cerebrospinal fluid rhinorrhea (author's transl)].

A series of 140 surgical cases of CSF rhinorrhea have been reviewed, their diagnostic difficulties outlined and the possible etiologies and the modes of surgical approach explained. The localization of the leak is difficult in traumatic cases but if one searches diligently for the source with polytomography of the skull base as well as utilizing repetitive radioisotope studies, one can definitely find the source of the rhinorrhea. If the patient presents with purulent meningitis, a fistulous tract, acquired or congenital, should be sought and if present resected. Only precise surgical technique in and around the skull base in cases of rhinorrhea, allows total definitive recovery without recurrent leak and prevents post operative rhinorrhea in routine basal and trans-sphenoidal neurosurgical procedures.

Brain Neoplasms↗
PubMedDate not supplied

[Endocrine prognosis of PRL-secreting pituitary adenomas. In 90 female cases (author's transl)].

This study based upon 90 cases of prolactinomas where hormonal and clinical results have been compared demonstrates: 1) a good correlation between a normal postoperative plasma PRL level (less than 30 ng/ml) and the cure of the amenorrhea galactorrhea syndrome (90% of the cases); 2) a good correlation between the cure of the patients and the preoperative plasma PRL level: below 200 ng/ml, 85% of the patients are cured compared to 24% only when the preoperative PRL plasma level is above 200 ng/ml.

Adenoma↗