[Reflectance spectra of flavonoids derived from Kubelka-Munk diffusion].
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Flavonoids↗
Biomedical subjects
A Villari
Publications and source records attributed to A Villari.
Quantitative analysis of pharmaceutical products containing tetracycline hydrochloride by computerized dispersive infrared spectroscopy.
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Computers↗
[Piperazine-2,5-diones-N,N'-substituted. II.-Substituted 1-phenyl-piperazine-2,5-diones-4-and hydrazone derivatives of N-phenyl-N-methylencarbethoxy-glyoxylamide].
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Amides↗
Evaluation of polyalkylcyanoacrylate nanoparticles as a potential drug carrier: preparation, morphological characterization and loading capacity.
Some physicochemical behaviours were investigated of polyethyl- (PECA) and polyisobutylcyanoacrylate (PICA), which, in recent years, have been proposed as nanoparticle colloidal systems for drug carrying. We observed the influence of preparation conditions, such as pH value and surfactant concentration, on parameters such as particle size and polymer molecular weight. Lower operating pH values (0-2) resulted in smaller nanoparticles than those prepared at pH 5.5. The polymer molecular weight was also a function of pH: low molecular weight at low pH and vice-versa. The surfactant concentration positively influenced main particle size and polymer molecular weight. These trends were independent of type of monomer; in fact, both ethyl- (ECA) and isobutyl-2-cyanoacrylate (ICA) showed the same behaviour. Loading capacity, as well as release profile, of the two polymers were evaluated using fluorescein as a model drug. Whereas both polymers showed almost the same release profile, there was a difference in the amount of encapsulated probe: higher aliquots for PICA than for PECA. Storage effects on such physicochemical parameters were also tested.
Chemistry, Pharmaceutical↗
Fast rolitetracycline stability determination by spectrophotometer variable-temperature kinetic experiments.
The pseudo-first order rate constant for the hydrolysis of rolitetracycline as a function of temperature was obtained by performing variable-temperature kinetic experiments. The results are in agreement with those obtained at constant-parameter kinetics but saving experimental time and chemicals.
Algorithms↗
[Thermal water of Alì Terme, Italy].
In this paper the history of the thermal water of Alì Terme (Sicily-Italy) and their beneficial effects are reported. Chemical and bacteriological investigations have been conducted for assay of thermophiles sulphur bacteria. As regards the chemical characteristics, traditional investigations have been carried out together with determination of H2S.
Balneology↗