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Biomedical subjects

A Vernes

Publications and source records attributed to A Vernes.

124 records · Page 7Linked to original sources

[Vulvar granuloma due to Enterobius vermicularis (author's transl)].

The authors report a case of casual discovery of a enterobiasic vulvar granuloma arising on the left labia. This woman, living in Lille (France), 70 years had been treated by surgery and roentgentherapy for a well differentiated squamous carcinoma of the vulva. They consider the question of the genital localisation of Enterobius vermicularis in women and discuss the pathogenic hypothesis.

Aged↗

[Morphology and infectivity of gametocytes of Plasmodium inui].

The authors report biomorphological changes of Plasmodium inui gametocytes during the natural infection of spleenless Macaca fascicularis. The infection was controlled up to the 42th day by smears produced by pricks into their ears (P.O.) and on blood taken at the same time by A. stephensi (P.M.). The first oocystes appeared on the 8th day after the infection in mosquitoes fed on the monkey parasitised in the eight day after splenectomy, as gametocytaemia was not detectable yet in the P.O. smears. The infectivity of gametocytes is highest on the 13rd day for a 152/10(4) parasitaemia. The first sporozoites appeared on the 18th day at 25 degrees C after the infecting meal. The sporozoites were infecting for a second monkey. Four morphological types (O, I, II and III) gametocytes were identified. They corresponded to the same types previously described in rodent Plasmodium. The maximum of infectivity coincided with a sudden increase in mosquitoe macrogametocytaemia; on the other hand the infectivity was very weak during the following peek of macrogametocytaemia which corresponded however to the maximum of parasitaemia (1 318/10(4) 18 days after splenectomy). When infectivity was important, there was a greater number of type O and I gametocytes in P.M. than in P.O. Eventually, the behaviour of P. inui gametocytes is, for the mainly, almost the same as that of rodent Plasmodium. However, it is to be noted that the identification of the 4 morphological types in P. inui is easier in macrogametocytes than in microgametocytes. The reverse had been observed in rodent Plasmodium.

Animals↗

[Ultrastructural study of oogenesis in Trichinella spiralis (author's transl)].

The ultrastructural study of oogenesis in T. spiralis makes it possible to subdivide the oocytic growth into 2 phases: a first phase is characterized by an intense nucleolar activity and the transfer of nuclear material to the cytoplasm; a second phase during which the cytoplasmic mass increases and energy reserves (glycogen, lipids) appear. The oocyte does not contain any protein vitellus.

Animals↗

[Serologic study of 51 cases of human trichinosis].

During the course of a recent epidemic of trichinosis two immunodiagnostic techniques were tested. Firstly indirect immunofluorescence (IF) using sections of the diaphram of infected mice and isolated trichine larvae. Secondly gel precipitation reactions, immunodiffusion and immunoelectrophoresis. It was observed that the induced specific antibodies appeared later than the clinical symptoms and the hypereosinophilia; the delay in appearance of the first positives detected being at least two to three weeks. Subsequently the titres rose rapidly and raised levels persisted for several months. Indirect immunofluorescence of excysted larvae remains the technique of choice, being rapid, sensitive and quantitative. The association of fluorescent and precipitation technique reduces the errors caused by cross reactions with other helminths.

Fluorescent Antibody Technique↗