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Biomedical subjects

A Vermey

Publications and source records attributed to A Vermey.

At least 73 records · Page 4Linked to original sources

Treatment of oral symptoms in Sjögren's syndrome.

The most pronounced oral symptoms in Sjögren's syndrome are a dry sensation of the mouth and difficulties in swallowing and speech. Besides these patients do no sleep well and may complain about burning mucous membranes, rampant caries and candidosis. Rampant caries can be prevented by optimal oral hygiene and frequent applications of a neural 1% sodium fluoride gel. Prophylaxis of candidosis can be obtained by meticulous oral hygiene and removal of predisposing factors (e.g. poor dentures). For the other oral signs of Sjögren's syndrome only a symptomatic treatment is possible, because damage of salivary gland tissue is progressive and irreversible. Good results can be obtained by applying a mucin-containing saliva substitute, which has been shown to reduce the dry an burning sensation of the mouth as well as to improve chewing, swallowing, speech and sleeping. When applied by an atomizer it wets the oral cavity for about 30 min. A continuous wetting can be obtained using intra-oral artificial saliva reservoirs.

Humans↗

Synovial chondromatosis of the temporo-mandibular joint. Report of three cases and a review of the literature.

Synovial chondromatosis of the temporo-mandibular joint is a rare affection, characterized by the formation of cartilage particles in the synovial membrane. These particles can break through and enter the joint compartments. The diagnosis must be considered for patients who complain of slowly progressive swelling, pain, and crepitus in the region of the temporo-mandibular joint. When the changes are not visible on plain X-rays due to absence of ossification, important diagnostic information can be obtained by a technetium 99m (99m Tc) bone scan and a computerized tomography (CT) sialogram. The diagnosis can be established only by histopathologic examination of surgically removed particles or resected synovial membrane. Discussed are 25 cases of histopathologically verified chondromatosis of the temporo-mandibular joint reported in the literature, as well as 3 new cases seen and treated at the University Hospital Groningen since 1970. A good clinical result can be obtained by removal of all particles and synovectomy. Condylectomy is seldom required.

Adolescent↗

Unilateral condylar hyperplasia combined with synovial chondromatosis of the temporomandibular joint. Report of a case.

A case of unilateral condylar hyperplasia combined with synovial chondromatosis of the temporomandibular joint (TMJ) is presented. Clinical and radiographic findings were consistent with an active unilateral hyperplasia. A high condylectomy was performed. During the operation numerous cartilaginous particles discharged from the TMJ and so it became clear that the patient was also suffering from chondromatosis. Both conditions were confirmed by histological examination.

Chondroma↗

Unexpected cure in metastatic rhabdomyosarcoma.

A 3 year old boy presented with a presumably incurable form of rhabdomyosarcoma. Conventional treatment for advanced stage rhabdomyosarcoma (chemotherapy plus radiotherapy) was not used and intensive chemotherapy alone was given, resulting in an apparent cure. Our treatment rationale is discussed.

Antineoplastic Combined Chemotherapy Protocols↗

[Dry mouth].

Explore the source record for details and available documents.

Humans↗

Radiographic imaging of lymph nodes in lymph node dissection specimens.

A new method of identifying and locating lymph nodes in lymph node dissection specimens using a radiographic imaging technique is described. The specimen is immersed in 96% ethyl alcohol which possesses a radiographic density similar to fat tissue. Even small immersed lymph nodes contrast well with 96% ethyl alcohol. Thus, a radiograph of a nodal dissection specimen, immersed in 96% ethyl alcohol, does not show the interfering projection of variations in thickness of the specimen. Simultaneously, lymph nodes are clearly imaged. Using this procedure, we could visualize 97% of all lymph nodes present in the fat tissue of lymph node dissection specimens, which were dissected free from large radiodense structures like muscle and submandibular glands. Thus, a simple method was established for radiographic documentation of lymph nodes in lymph node dissection specimens.

Humans↗

Leiomyo(sarco)ma of the oesophagus.

Leiomy(sarco)mas of the oesophagus are rare tumours, which often cause ill-defined disturbances in the passage of solid food. The diagnosis can be established by simple radiological examination and endoscopy. There is no infiltration of the mucosa and it is undesirable to take biopsy specimens from such tumours through intact mucosa. The treatment of choice of leiomyoma is enucleation; that of leiomyosarcoma is resection.

Adult↗

The significance of the doctor-patient relationship in coping with cancer.

The uncertainty and anxiety experienced by cancer patients and their ways of coping with uncertainty and anxiety were studied on the basis of a questionnaire completed by 418 patients. The study shows that 28.2% of the patients had a low and 33.5% had a high uncertainty score, while 50% had a low and 9% had a high anxiety score. Four ways of coping with uncertainty and anxiety can be distinguished, of which the use of self-instruction means was most common. Expert help proved to be important for reduction of uncertainty. For reduction of anxiety the support of the home environment and of fellow-patients was also of importance. The implications of these findings for the doctor's performance and for the care of cancer patients are discussed.

Adaptation, Psychological↗

Rheological properties of saliva substitutes containing mucin, carboxymethylcellulose or polyethylenoxide.

Apparent viscosities at different shear rates were measured for 3 types of saliva substitutes: (a) mucin-containing saliva; (b) substitutes based upon carboxymethylcellulose (CMC), and (c) solution of polyethylenoxide (PEO). The apparent viscosities were compared with those of human whole saliva. Human whole saliva and mucin-containing saliva substitutes appeared to be similar in their rheological properties. Both types of solution are viscoelastic solutions and adjust their apparent viscosities to their biological functions. Preparations containing CMC or PEO are non-Newtonian liquids. From this study it is concluded that mucin-containing saliva substitutes appear to be the best substitutes for natural saliva, as far as rheological properties are concerned.

Carboxymethylcellulose Sodium↗

CT scanning of tumors in or near the parotid or submandibular glands. A comparison with conventional sialography.

Plain computed tomography (CT) scanning and CT scanning after injection of contrast medium into the salivary glands (CT sialography) were compared with conventional sialography in 50 patients with neoplasms in or near the parotid or submandibular glands. The results were correlated with clinical and pathological findings. CT sialography proved to be the best diagnostic method in the diagnosis of salivary gland tumors.

Adenolymphoma↗