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Biomedical subjects

A Verma

Publications and source records attributed to A Verma.

At least 181 records · Page 10Linked to original sources
PubMed1990

Focal neuropathy preceding chronic inflammatory demyelinating polyradiculoneuropathy by several years.

We report three patients who exhibited an unusual clinical course of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in which mononeuropathic limb weakness developed 2, 11 and 23 years, respectively, before the development of generalized polyradiculoneuropathy. The eventual diagnosis remained uncertain until other causes of neuropathy were excluded, and the clinical disorder progressed to involve the other limbs. Focal or regional variants of CIDP suggest that the pathologic, and perhaps the immunologic, abnormalities can be localized and selective for prolonged periods of time. Although this clinical variant seems to account for a small number of CIDP cases, its recognition may aid in making an early diagnosis.

Adult↗
PubMed1990

Venoruton as a radioprotector: a haematological assessment.

Efficacy of Venoruton--O-(hydroxyethyl) Rutoside--as a radioprotector has been tested on haematological profile of rats which were subjected to whole body radiation (500 rads). The results show radiation induced lesions in respect of total (TLC) and differential leukocyte counts (DLC)/and haemoglobin are significantly lessened when Venoruton was administered prior to radiation exposure.

Animals↗
PubMed1990

Synovial sarcoma of the nasopharynx.

A case of primary synovial sarcoma of the nasopharynx in a 28-year-old man is presented. The patient was treated with operation followed by radiotherapy and is free of recurrence or evidence of metastasis 40 months after treatment. Because of the extreme rarity of this tumor in this site, the importance of its recognition is stressed.

Adult↗
PubMed1990

Pseudopsychopathic syndrome in hydrocephalus: a case report and review.

A 24-year-old man with a head injury developed a communicating hydrocephalus and underwent ventriculoperitoneal shunting. A revision was required, and the patient emerged from coma with severe behavior outbursts, which persisted for more than 1 year. Computed tomographic scans indicated a recurrence of low-pressure communicating hydrocephalus and a shunt revision was performed. The patient's severe behavior outbursts immediately decreased dramatically. The improvement continued long term and extended beyond the acute rehabilitation program.

Adult↗
PubMed1990

Normokalaemic periodic paralysis as the presenting manifestation of hyperthyroidism.

We report a 50 year old male admitted with complaints of episodic weakness. During the attack of paralysis there was no hypokalaemia. There were no clinical signs of thyrotoxicosis, but since thyroid function tests revealed hyperthyroidism, he was treated as a case of thyrotoxic periodic paralysis, with no recurrence of symptoms over 6 months.

Humans↗
PubMed1989

Adult-onset autosomal recessive neurogenic scapuloperoneal syndrome.

We report a brother and sister who showed weakness, atrophy and fasciculations starting in adulthood, predominantly affecting the muscles of the shoulder girdles and distal lower extremities. Mild ptosis and facial weakness were present in both. Electrophysiological studies and muscle histology supported a neurogenic basis for the autosomal recessive scapuloperoneal syndrome in this sibship.

Adult↗
PubMed1989

Serum copper levels in gastrointestinal tract (GIT) cancer.

Cancer of the gastrointestinal tract (GIT) is very commonly encountered in Kashmir Valley of India. Serum copper and ceruloplasmin levels were investigated in 75 patients with GIT cancer, 42 non-GIT cancer and 75 normal healthy controls. The mean serum copper in the control group was 1,078 (S.D. 0,296) mg/L, while in patients with GIT and non-GIT cancers, it was 1,738 (S.D. 0,675) and 1,449 (S.D. 0,501) mg/L. Copper in both types of cancers showed significant increase (p less than 0.001). It was significantly higher in GIT cancers (p less than 0.01) as compared to non-GIT cancers. Ceruloplasmin in controls was 379 (S.D. 51) mg/L, while in GIT and non-GIT cancer patients the values were 363 (S.D. 75) and 364 (S.D. 77) mg/L, respectively. No significant difference could be found in either of the groups. In Kashmir Valley, the copper content in body tissues is likely to be on the high side because copper utensils are widely used by the general population. Water and milk samples stored in copper vessels and salt tea prepared in copper vessels showed markedly high levels of copper.

Animals↗
PubMed1989

Primary tuberculosis of the tongue.

Primary tongue tuberculosis is an uncommon condition, and there is a paucity of such cases in the literature. We report a case of primary tuberculosis of the tongue in a 55-year-old man.

Humans↗
PubMed1989

Post laryngectomy complications and their mode of management--an analysis of 203 cases.

Two hundred and three laryngectomized patients have been evaluated for the possible causes of post operative complications. 58 out of 203 patients (28.5%) developed pharyngocutaneous fistula. Wound infection was present in 57 cases (28%). Two patients had flap necrosis and 12 patients developed dysphagia after surgery due to pharyngeal stenosis. The possible causes attributed to high occurrence of pharyngocutaneous fistula are, advanced nature of disease, preoperative radio therapy and wound sepsis. Prior to 1980, the incidence of pharyngocutaneous fistula in our series (Arora et al. 1983) was 41.6 percent. But it decreased to 13.7 percent between January 1981 to June 1987. The important factors which led to the decreased incidence of pharyngocutaneous fistula were thought to be the change of suture material for pharyngeal repair from chromic catgut to Vicryl, use of vacuum suction as a replacement of corrugated rubber drain and aseptic syringe drainage and postoperative coverage with broad spectrum antibiotics.

Adult↗
PubMed1988

Dermoid tumours occurring at the site of previous meningocele repair.

Two cases of dermoid tumours following meningocele repair have been reported because of the rarity of the condition and paucity of literature. It should be stressed that a dermoid tumour should be considered in the differential diagnosis of neurological deterioration in patients with a repaired meningocele.

Adult↗
PubMed1988

Characterization of porphyrin interactions with peripheral type benzodiazepine receptors.

We have examined organ and species variations in interactions of porphyrins with peripheral-type benzodiazepine receptors and explored structure-activity requirements for porphyrin-receptor interactions. Whereas potency of the benzodiazepine RO5-4864 varies several orders of magnitude in competing for receptors in different organs and species, effects of porphyrins and the isoquinoline carboxamide PK11195 are relatively constant. The structural requirements determining porphyrin affinity for benzodiazepine binding sites are fairly strict. The most potent porphyrins are those with prominent physiological functions.

Animals↗