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Biomedical subjects

A Venco

Publications and source records attributed to A Venco.

At least 91 records · Page 5Linked to original sources
PubMed1978

Noninvasive assessment of left ventricular function in myotonic muscular dystrophy.

In order to assess left ventricular function, measurements of left ventricular internal dimension and its rate of change have been made by echocardiography in 7 patients with myotonic dystrophy and the three children of one of them, who were clinically normal but had abnormal muscle biopsies. Electrocardiograms and systolic time intervals were also recorded in all. Only one patient had signs of overt heart disease and an abnormal electrocardiogram (type B WPW). Systolic time intervals were normal in all 7 patients. Five subjects had echocardiographic abnormalities, which were of minor degree except in the patient with overt heart disease who had considerable impairment of both systolic and diastolic left ventricular function. Another patient had abnormalities of both systolic and diastolic function; systolic abnormalities occurred alone in one patient and diastolic abnormalities alone in one relative. It is concluded that patients with myotonic dystrophy and no clinical signs of heart disease may have minor abnormalities of left ventricular function as shown by echocardiography. Echocardiography is more sensitive than systolic time intervals in detecting these abnormalities; both systolic and diastolic function abnormalities, alone or together, can occur. There seems to be no relation between involvement of skeletal and cardiac muscle.

Adolescent↗
PubMed1977

Relation between apex cardiogram and changes in left ventricular pressure and dimension.

The relation between the apex cardiogram and changes in left ventricular pressure measured by micromanometer, and dimension measured by echocardiography, was studied in 12 normal subjects and 64 patients with heart disease. In 12 patients, the apex cardiogram was delayed with respect to simultaneous left ventricular pressure by 17 +/- 18 ms during the upstroke and 28 +/- 16 ms during the downstroke. In the normal subjects, changes in left ventricular dimension during the upstroke and downstroke of the apex cardiogram were small, amounting to 6 +/- 5 and 21 +/- 7 per cent total excursion, respectively. In 10 patients with mitral regurgitation, there was significant inward wall movement during the upstroke and in 10 patients with aortic regurgitation, significant outward movement during the downstroke, both reflecting valvular regurgitation. In 20 patients with ischaemic heart disease and segmental abnormalities on left ventricular angiography, apex cardiogram-echo dimension relations were abnormal in all, because of inward or outward wall movement during the upstroke, increased outward movement before the 'O' point, or abnormal inward movement during the downstroke. These disturbances were displayed by constructing apex cardiogram-echo dimension loops, which appear to be a sensitive means of detecting incoordinate left ventricular contraction, analogous to those between pressure and dimension.

Adolescent↗
PubMed1977

A study of pulmonary artery pressure, electrocardiography, and mechanocardiography in thoracic scoliosis.

Cardiac catheterisation was carried out in 40 patients with thoracic scoliosis in order to measure the pulmonary artery pressure. Statistical correlations were calculated between these results and the electrocardiographic and mechanocardiographic findings determined on a separate occasion. The pulmonary artery pressure was normal in 72% of subjects. It was inversely correlated with arterial oxygen tension but not with the aetiology, severity, or age at onset of the scoliosis. The accuracy of electrocardiography and mechanocardiography in predicting the pulmonary artery pressure was assessed. The closet correlates were found to be a tall P wave in lead II or III and a prolonged interval between pulmonary valve closure and tricuspid valve opening.

Adolescent↗
PubMed1976

[Contribution of the mechanocardiography to the study of obstructive chronic bronchopneumopathy].

Kinetocardiography, ECG and radiography, were compared as ways of obtaining early diagnosis of chronic cor pulmonale in two series of patients (81 in all) with chronic obstructive bronchopneumopathy. Kinetocardiography proved markedly superior in this respect. It revealed right ventricular pressure overload in a higher percentage of cases and at an earlier stage, i.e. when PAP values were little above normal resting values, of even when their increase appeared only during physical effort.

Adult↗
PubMed1976

Non-invasive assessment of left ventricular function after correction of severe aortic regurgitation.

Twenty patients were studied with simultaneous left ventricular cavity echocardiograms and apex cardiograms during the first two weeks after correction of severe aortic regurgitation. Endocardial echoes and apex cardiograms were digitized, so that left ventricular dimensions, their rates of change, and echo dimension-apex cardiogram relations could be studied. After aortic valve replacement, there was an early reduction in end-diastolic dimension, within 2 days, from 7-0 +/- 0-8 cm to 5-7 +/- 1-0 cm (P less than 0-001), while peak normalized shortening rate (peak Vcf) dropped from 1-9 +/- 0-6 to 1-4 +/- 0-6 S-1 (P less than 0-01), and remained unchanged for the remainder of the study. Immediately after operation, striking abnormalities of isovolumic contraction and, to a lesser extent, of early relaxation, could be seen, which regressed over 4 to 7 days, except in 2 patients who developed a low output state. These changes in left ventricular dimension, Vcf, and isovolumic contraction could not have been described by an single "measure" of left ventricular function.

Adolescent↗
PubMed1976

[The kinetocardiogram in complete left bundle branch block. Correlations between the kinetocardiogram and systolic time intervals (author's transl)].

The authors studied the possible correlations between the behaviour of the systolic time intervals, as measured by the electrophonosphygmographic patterns, and the behaviour of the kinetocardiogram recorded on left precordium, in 23 cases of complete LBBB. The results tend to confirm the possibility of distinguishing the distal from the proximal level of the conduction defect in a non invasive way, as already indicated in literature. Evidence for the former is the observation of a lengthening of the isovolumetric contraction time, of an increase of the PEP/LVET and ICT/LVET ratios, of a pansystolic bulge in KCG with a pathological amplitude of the atrial waves, all showing a left ventricular dysfunction. Evidence for a proximal level of conduction defect is: the normal length of the ICT, the normal PEP/LVET and ICT/LVET ratios, the absence of pathological atrial waves in KCG. The presence of paradoxical outward movement (POM) in KCG also in the latter case, even though only rarely observable as a pansystolic bulge, could be related to the existence of a form of ventricular dyssynergy, due to the deranged conduction of the impulse (ventricular dyskinesis from inter- or intra-ventricular asynchrony).

Adolescent↗