The solubilization of mature, polymeric collagen fibrils by lyotropic relaxation.
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Biomedical subjects
Publications and source records attributed to A Veis.
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The ability of 2 calcium hydroxide-containing materials to induce initiation of reparative dentinogenesis was tested at sites remote from the dentinogenically-active regions of the pulp periphery. Pieces of the cements, Dycal and Life, were implanted in central parenchymal sites of dog dental pulps for periods of 6, 14 and 42 days, respectively. Similar pieces were placed in peripheral capping sites as controls. The responses were analyzed by light and transmission electron microscopy. Induction of tubular dentin matrix lined with elongated and polarized odontoblast-like cells was only seen at peripheral capping sites. In response to the centrally implanted cements, only atubular hard tissue with lining fibroblast-like cells was deposited.
Collagen synthesis and subsequent extracellular stabilization and turnover are multi-step processes. The sequence of events in these processes is reviewed and correlated with collagen pathologies.
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