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Biomedical subjects

A V Zubarev

Publications and source records attributed to A V Zubarev.

At least 19 recordsLinked to original sources
PubMed2005

[Ultrasonic technologies in diagnosis and surgery planning in patients with nodular pathologies of the thyroid gland].

Twenty patients of the control group without pathology of the thyroid gland were examined for development of the method of 3D-ultrasonic reconstruction and 3D-angiography. The study group consisted of 74 patients with nodular pathologies of the thyroid gland, 53 of them underwent surgery. Ultrasonic data was compared with results of clinical and laboratory studies, puncture biopsy and intraoperative data. Three-dimensional ultrasonic pictures permitted to detect spatial orientation of the nodes relative to lobes and segments of the thyroid gland, vascular structures, to evaluate character of nodes vascularization, to analyze nature and invasiveness of the tumor. Based on these data optimal variant of surgery was chosen. In 12 cases virtual modeling of surgeries with 3D-echography and ultrasonic angiography was performed. These methods permit to choose optimal variant of surgery and make possible prediction and prevention of complications.

Angiography↗
PubMed2001

Ultrasound of renal vessels.

Kidneys are known as well-perfused organs and may undergo a variety amount of vascular pathological conditions such as renal artery stenosis, renal vein thrombosis, arteriovenous fistula, and aneurysms. Sonography is usually the first imaging method for renal vascular diseases. Modern US machines are now able to outline with great detail both main renal vessels and intraparenchymal vasculature of the kidney using color and power Doppler techniques. Knowledge about the use of different Doppler imaging modalities and typical sonographic findings of the most frequently conditions affecting renal vessels are of great importance. This article reviews the clinical applications of US and Doppler US techniques including basics and technological advances in the field of renal vascular diseases.

Aneurysm↗
PubMed2001

[Ultrasonic examinations of thyroid newgrowths].

The results of complex ultrasonic, histological and cytological examination of 148 patients with newgrowths thyroid were analyzed. Grey-scale mode, colored and energy Doppler scanning, three-dimensional reconstruction of vessels were used. A new classification of nodular vascular pattern types based on 3-D reconstruction is proposed. The majority of malignant formations were characterized by perinodular hypervascularization and internodular hypovascularization (82.4%), adenomas--by peri- and intranodular hypervascularization (88.9%), colloid nodes--by perinodular hypervascularization (85.5%), the blood flow was absent in simple cysts (85.3%). It was established that complex of these methods increases informative value of ultrasonic examination in diagnosis of thyroid nodular diseases: in malignant neoplasms the sensitivity is 92.9%, specificity--86.1%, diagnostic accuracy--86.9%, in adenomas--93.4%, 79.2% and 82%, in colloid nodes--75.7%, 84.1% and 79.8%, respectively. In cystic masses diagnostic value of Doppler methods didn't change: sensitivity was 90.4%, specificity--63%, diagnostic accuracy--80.5%. The combined ultrasonic examination provides a differential approach to treatment of patients with thyroid nodular masses and decreases the number of unjustified surgical interventions.

Adolescent↗
PubMed2001

[Ultrasound angiography: new perspectives in diagnosis of renal mass lesions].

AIM: To evaluate diagnostic efficacy of advanced ultrasound (US) techniques in early and differential diagnosis of malignant tumors of the kidneys. MATERIAL AND METHODS: A total of 394 patients with renal mass lesions were studied. They had: renal cell carcinoma (n = 96), renal parenchyma pseudotumors (n = 22), lipoma (n = 48), angiomyolipoma (n = 19), renal abscess (n = 2), renal sinus lipomatosis (n = 1), parenchymal cysts (n = 205), retroperitoneal leiomyosarcoma with invasion in the kidney (n = 1). The following examinations were made: gray scale study with tissue harmonic imaging, panoramic scanning, US-angiography (color doppler imaging--CDI, power doppler imaging--PDI, 3D-reconstruction of the kidney vessels, 3D dynamic contrast enhanced angiography (DCEA) in the second harmonic mode with an echo-contrast agent levovist. Pulse Doppler with qualitative and quantitative evaluation of the doppler spectrum was used as an additional method. Verification of the diagnosis was made by conventional angiography, computer tomography, MR-tomography, histomorphological analysis after surgery in 91, 310, 6 and 88 patients, respectively. RESULTS: New US techniques allow differentiation of malignant tumors with renal lipomas and angiomyolipomas, focuses of inflammation, pseudotumors of the renal parenchyma and atypical renal cysts. CDI has revealed big pathologic vessels with arterio-venous and arterio-arterial shunts in renal cancer in 63.5% of the cases. PDI visualized a net of pathologically changed vessels in 74.8% of the cases. 3D-reconstruction in PDI was highly sensitive (90%) in visualization of neoplastic vessels. US-angiography was used for pre- and postoperative monitoring in 18 patients subjected to conservative renal surgery. In 23 patients DCEA with levovist allowed monitoring of all phases of contrast enhancement of renal vessels. Injection of contrast agent revealed tumor microvasculature in an early arterial phase (20-30 seconds). CONCLUSION: US-angiographic techniques in diagnosis of renal cancer increases sensitivity and specificity of the US method compared to conventional B-mode US from 55 and 60% to 98 and 95%, positive and negative predictive value from 58 and 57% to 95 and 98%, respectively.

Angiography↗
PubMedDate not supplied

[Conservative surgery of renal cancer].

Organ-preserving technologies are coming up to take the place of organ-removing operations for cancer of the kidney. A tumor size is not a decisive parameter any more as the decision is made in each individual case. Ultrasound, as a screening test, has changed the situation in the diagnosis of early stages of the disease, but routine urological examinations retain their importance. Postoperative monitoring with US angiography is essential for detecting relapses.

Decision Making↗
PubMedDate not supplied

[Diagnosis of bladder cancer].

Increasing incidence of bladder tumors necessitates development of new techniques of early diagnosis. A total clinical system including application of ultrasonoangiography proved superior to examination under the gray scale mode. The diagnostic and monitoring algorithm makes the system highly effective.

Aged↗