Disease concomitance in psoriasis.
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Biomedical subjects
Publications and source records attributed to A V Wahba-Yahav.
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A 54-year-old man experienced an extensive asymptomatic purpuric eruption on both his legs consistent with Schamberg's purpura. Three months before, he had had an episode of acute viral hepatitis. Nine months later, the purpura was unchanged despite administration of a topical corticosteroid. Results of serologic evaluation revealed hepatitis B surface antigen. The patient was treated orally with pentoxifylline, 400 mg three times daily. After one month of therapy, the purpuric elements of his eruption had disappeared, and after two additional months most of the pigmentation had also faded.
A unique patient with a painful transient erythematous blotchy eruption of the face, neck, and upper trunk is described. Administration of oral diclofenac sodium resulted in prompt control of the condition. The possible relationship of this syndrome with erythermalgia is reviewed.
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A 60-year-old HIV-negative man with known noninsulin-dependent diabetes mellitus and glucose 6-phosphate-dehydrogenase deficiency anemia suffered from chronic recurrent furunculosis since the age of 30. In recent years, his condition had become increasingly severe and the recurrences increasingly frequent. Different measures including continuous therapy with large doses of systemic antibiotics for a period of 6 months failed to prevent the recurrences. Oral treatment with pentoxifylline 400 mg t.i.d. was prescribed, and 2 months later the patient experienced a dramatic and complete remission of his furunculosis. Six months later he was still totally free of lesions while continuing to take the same medication. Pentoxifylline may provide a new and effective approach to the previously difficult and often disappointing problem of the management of patients with chronic recurrent furunculosis.
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