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Biomedical subjects

A V Greco

Publications and source records attributed to A V Greco.

At least 217 records · Page 12Linked to original sources
PubMed1978

Urinary kallikrein excretion and plasma DBH activity in hypertension.

Many factors are to be considered in maintaining normal blood pressure. Authors study the behavior of urinary kallikrein (U.K.) and plasma dopamine-beta-hydroxylase (DBH) activity in various forms of hypertension. The values of U.K. excretion in normals were 20.5 +/- 1.8 E.U./24 h. In essential hypertensive patients (9.4 +/- 2.0 E.U./24 h) U.K. decreased, while in secondary hypertension it was significantly higher (33.8 +/- 3.0 E.U./24 h). Plasma DBH activity in essential hypertensive patients (17.72 +/- 2.33 I.U./ml) was similar to controls (20.22 +/- 1.39 I.U./ml); in secondary hypertension the mean values of plasma DBH were decreased (12.31 +/- 2.55 I.U./ml). No correlation between U.K. and plasma DBH activity was observed in normals and in various forms of hypertensive patients. U.K. seems a more reliable factor than plasma DBH in defining the different types of hypertension.

Adolescent↗
PubMed1978

Insulin receptors during the menstrual cycle in normal women.

Specific binding of 125I-insulin to circulating monocytes from eight normal menstruating women, four postmenopausal women and four men were studied four times during a 28-day period (one sample at 7-day intervals). Data indicate the presence of a higher specific cell binding fraction in the follicular phase compared to the luteal phase due to changes in insulin receptor concentration. No changes were observed in men or postmenopausal women during the same period of time suggesting that sex hormones should be included among the factors influencing insulin receptors.

Adult↗
PubMed1976

[Changes in plasma insulin and growth hormone after intravenous glucagon in hepatic cirrhosis].

Decreased increases in blood sugar by comparison with control subjects was noted in patients with cirrhosis of the liver after i.v. administration of 1 mg glucagon. Insulin secretion was similar to that observed in the controls. Basal GH values were higher in the liver patients, whereas after glucagon they displayed a gradual and progressive increase with a peak at 60'. No significant differences in GH pattern were noted in the two groups, however.

Adult↗
PubMed1976

[GH secretion after L-dopa administration in hepatic cirrhosis].

A 500 mg L-Dopa administration in normal and cirrhotic subjects does not determinate a significant varation of plasma glucose and insulin level, while a peak plasma GH level in both cirrhotic and normal subjects occurred at 90' with a significantly greates values in cirrhotics. It is doubtful to affirm that a high plasma GH level is the only one factor which responsable of glucose intolerance in cirrhotic subjects, when there are many others factors contribute to it in synergic way. In order to elucidate the hypothesis on possible pathogenetic mechanism it is discussed some of our own experience and observations.

Adult↗
PubMed1976

[Secretion of GH and diabetic retinopathy].

Recently it has been studied a possible pathogenetic role of GH in diabetic angiopathy. The purpose of the present study was to verify whether the diabetic retinopathy is associated or not with a high plasma GH level. In an attempt to answer this question we did the dosage of plasma GH after a oral glucose load (110 g), Insulin (0,1 U/Kg) i.v., and arginin i.v. (25 g/30'). The plasma GH measurements were approximately the same as in normal patients. The Authors underline the importance of GH in pathophysiology of diabetic angiopathy and report all recent literature on this argument.

Adult↗
PubMed1976

[Plasma insulin and GH during oral glucose load in liver cirrhosis].

Blood sugar, insulin and GH values were examined in two groups of cirrhosis of the liver patients, with and without ascites, after the administration of 100 g glucose per os. No significant differences between the two groups were observed. Insulin values were higher than those in the controls, with a pattern similar to that noted in subjects with chemical diabetes. GH values were higher than in normal subjects and secretion was not suppressed.

Adult↗
PubMed1975

[The association of diabetic disease with Friedreich's disease in members of the same family].

Friedreigh's disease is only rarely associated with diabetes mellitus and only few cases are to be found in the literature, especially as regards siblings. Three cases of this association in members of two different families are reported. Two of the patients died from cardiovascular complication; the third case is that of a 32-yr-old woman who was able to complete a pregnancy. The pathogenesis of the association is discussed and a number of theories are put forward. The most generally accepted genetic hypothesis makes it possible to explain under a common metabolic denominator neurological disturbances and those in other systems. The association is not a purely casual event but is perhaps dependent on either two different genes or on a single gene with pleitropic effect. Heart signs are frequent in Friedreich's disease and brief mention is made of these.

Adult↗
PubMed1975

[Simple glaucoma and diabetic disease].

Blood sugar, blood insulin and the insulinogenic index after oral glucose were studied in 41 subjects with simple glaucoma. Clinical diabetes was present in 9.76% and asymptomatic diabetes in 21.95%. It is suggested that a high incidence of diabetes may be expected in simple glaucoma, probably as expressions of a common genetic disorder.

Adult↗
PubMed1975

[Urinary kallikrein excretion in hepatic cirrhosis].

Measurements of urinary kallikrein using an esterolytic assay revealed higher levels in patients with liver cirrhosis than in a control population. The range of excretion in 33 patients with cirrhosis was from 18.68 to 85.20 E.U. per 24 hours with a mean excretion of 39.42 plus or minus 2.84 E.U. Kallikrein excretion in the control group ranged from 13.20 to 39.50 E.U. per 24 hours with a mean of 24.44 plus or minus 1.66 E.U.

Adult↗