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Biomedical subjects

A V Bol'shunov

Publications and source records attributed to A V Bol'shunov.

At least 19 recordsLinked to original sources
PubMed2003

[Experimental and morphological as well as physical and chemical interaction of laser radiation of a close infrared range with the fibrous eye membrane].

Experimental-and-morphological as well as physical-and-chemical changes occurring in the eye fibrous coat tissues, i.e. the cornea and sclera, at non-ablation impact of fiber laser radiation (Er-glass) with a wavelength of 1.56 mcm were analyzed. Necrobiotic or necrotic changes occur in the tissues with regard for laser radiation capacity and impact duration; subsequently, the regenerative process involving a retraction of the sclera and a flattening of the cornea takes place in the end. When the cornea is heated by fiber laser radiation with a minimally possible intensity (up to 0.3 Wt), a temporary weakening is observed in the corneal rigidity. Should it be accompanied by a simultaneous occurrence of retraction forces coming from the sclera (at its coagulation), it can be used to change, in the clinical controllable mode, the corneal curvature radius.

Cornea↗
PubMedDate not supplied

[Current techniques of laser therapy in glaucoma].

The role of new technologies in glaucoma treatment, related with the use of semi-conductor laser irradiation, is described. Indications for laser therapy in glaucoma of different types have been significantly enlarged. Diode laser trabeculoplasty (DLTP) is a qualitatively new surgery based on the traction and perforation components. Diode transscleral cyclocoagulation (DTCC) enabled treatment of late stages glaucoma (sub-terminal and terminal ones), which previously was not subject to laser therapy. A combined method (DLTP and DTCC) ensured, in many cases, an effective treatment of resistant and already-operated glaucoma.

Glaucoma↗
PubMedDate not supplied

[Results of photodynamic therapy of subretinal neovascular membranes according to the data of fluorescence angiography and optical coherence tomography].

We studied the possibilities of the method of photodynamic therapy (PDT) in the treatment of subretinal new-vascular membranes. The results of PDT in 28 patients (28 eyes) with subretinal new-vascular membranes of different etiologies were evaluated by using the techniques of fluorescent angiography and optic coherent tomography. A reduced membrane area was noted in 17 patients (17 eye), and an improved visual acuity was registered in 7 patients (7 eyes). The use of PDT makes it possible, in a number of cases, to prevent the reduction of visual functions and even to improve them in patients with subretinal new-vascular membranes. The use of diagnostic opportunities of fluorescent angiography and optic coherent tomography is an indispensable part belonging to the monitoring of the conducted treatment.

Aged↗
PubMedDate not supplied

[Laser-correlation spectroscopy of the lacrimal fluid in the evaluation of the semiotic nature of postoperative inflammatory reaction and the degree of its severity in patients with diabetes mellitus after intraocular lens implantation].

Lavages of the lacrimal fluid were examined, before operation and immediately after operation, in 47 patients with diabetes mellitus and with pseudophakia in order to define the possibilities of the method of laser-correlation spectroscopy (LCS) in evaluating the semiotic nature and a severity degree of postoperative inflammation. It was found that, when the subjective symptomatology of inflammation in the LCS spectrums intensified, there was a higher contribution to the light dissemination of particles with a hydrodynamic diameter of 600 nm and more (i.e. of heavy lipoprotein complexes and of immune complexes), which were determined after a computer-based processing as a condition of primary intoxication and of immune shifts. The LCS results objectively confirmed that the degree of inflammatory changes during the early postoperative period was reliably higher in patients with a level of glycolyzed hemoglobin exceeding 9% versus patients with the above parameter being below 9%.

Diabetes Complications↗
PubMedDate not supplied

[Comparative evaluation of the efficiency of transscleral diode laser cyclophotocoagulation during contact and contactless procedures: experimental morphological study].

To elucidate the extent to which contact and contactless procedures of diode laser transscleral cyclophotocoagulation (CPC) has a antihypertensive effect and a ocular tissue damaging effect, the authors have made a comparative assessment of the procedures to determine their preference. The study was conducted on an experimental material (5 Chinchilla rabbits (10 eyes)). The follow-up was 1 day to 6 months after laser interventions. The authors estimated the parameters of ocular hydrodynamics before and laser intervtntion throughout the follow-up and analyzed them with morphological changes kept in mind. The final antihypertensive effect of both contact and contactless procedures was virtually equal. However, less inflammatory changes and lower ocular damaging effect, and no additional medical manipulations for contactless diode laser CPC make it more preferable to contact CPC for clinical use.

Animals↗
PubMedDate not supplied

[Possibilities of the clinical use of a new Soviet laser device on the anterior and posterior segments of the eye].

A new Soviet laser device for multiple-purpose ophthalmologic application is described. The design is based on neodymium-doped glass laser with radiation at a 1.06 micron wavelength in a Q-spoiled mode and YAG laser with radiation frequency doubling at a wavelength of 0.532 micron in continuous operation. Clinical potentialities of this laser design in the treatment of abnormalities of the anterior and posterior segment of the eye were studied in the treatment of 48 patients (48 eyes). The results evidence that the device is fit for coagulation as well as for mechanical destruction of tissue.

Anterior Eye Segment↗