Search PubMed⌕ Search

Biomedical subjects

A V Andreev

Publications and source records attributed to A V Andreev.

At least 19 recordsLinked to original sources
PubMed2001

Coulomb blockade oscillations in the thermopower of open quantum dots.

We consider Coulomb blockade oscillations of thermoelectric coefficients of a single electron transistor based on a quantum dot strongly coupled to one of the leads. An analytic expression for the thermopower as a function of temperature T and the reflection amplitude r in the quantum point contact is obtained. Two regimes can be identified: T< >EC/r/2, where EC is the charging energy of the dot. The former regime is characterized by a weak logarithmic dependence of the thermopower on the reflection coefficient, in the latter the thermopower is linear in the reflection coefficient /r/2 but depends on temperature only logarithmically.

Journal Article↗
PubMed2000

Compression of femtosecond laser pulses in thin one-dimensional photonic crystals.

We demonstrate experimentally the effect of compression of femtosecond laser pulses in thin (a few micrometers) one-dimensional photonic crystal. We show that the compression effect is reasonably described by the linear dispersion properties of the photonic crystal itself and the quadratic dispersion approximation cannot be efficiently used for the description of interaction of the femtosecond laser pulses with the thin photonic crystal. For given parameters of the femtosecond pulse it leads to the existence of the optimal dimension of the photonic crystal from the point of view of the compression efficiency. Due to the wide spectral width of the femtosecond laser pulses the high-order dispersion effects play an important role in pulse propagation in photonic crystals and as a result the pulse compression occurs for both positive and negative signs of chirp of the incoming femtosecond pulses.

Journal Article↗
PubMed1998

[A variant of radioimmunoassay of alpha-fetoprotein].

A variant of liquid-phase radioimmunoassay (RIA) with murine monoclonal antibodies E7(B2-1) to human alpha-fetoprotein (AFP) is described. AFP levels were measured by RIA with a commercial DIAplus kit in the sera of patients with germinogenic tumors and of pregnant women.

Antibodies, Monoclonal↗
PubMed1994

[Transcranial dopplerography and variational pulsimetry in the diagnosis of cerebral angiodystonias in children].

The hypoxemia-hypercapnia test with closed-space breathing has been performed in 71 children aged 9-15. The examinees comprised three groups: healthy controls (n = 12), patients with latent cerebral angiodystonia (n = 9), patients with clinical cerebral angiodystonia (n = 50). The patients could hardly tolerate closed-space breathing. They complained of head aches, dizziness, suffered from vegetative stigmas, neurological deficiency. In subclinical and apparent disease vegetative dysadaptation predominated in the parasympathetic and dysregulatory forms. The load-provoked increase in the linear blood flow rate and a decrease in the resistance index appeared more pronounced in the controls. This evidences reduced adaptive potential of brain autoregulation in patients with cerebral angiodystonia.

Adolescent↗
PubMed1989

[Ways of reducing mortality in perforated ulcer of the stomach and duodenum].

Based on an analysis of lethal outcomes in 20 of 326 patients with perforated ulcers of the stomach and duodenum the authors recommend to perform planned operations more often in elderly and senile patients, to combine suturing the ulcer with truncal vagotomy, intensive therapy, administration of drugs, catheterization of the superior mesenterial artery.

Adult↗
PubMed1989

[Hematologic indicators in patients with morbid obesity after surgical creation of the miniature stomach].

Surgical establishment of miniature stomach was conducted in 28 patients with severe alimentary-constitutional obesity (mean body weight 155.7 kg). After a 18-36-month follow-up the patients underwent hematological examination. It was found that a 134% excess of body weight registered preoperatively dropped to 54%. Reduced levels of blood red cells, hemoglobin, serum iron were not registered. Neither was anemia. This shows that physiological function of the whole gastrointestinal tract was not damaged, the blood loss appeared insignificant. Substitution therapy with hemostimulants during the following two years may be avoided.

Adult↗
PubMed1988

[Use of the leukocyte mass in treatment of patients with suppurative lactation mastitis].

The application of leukocyte mass against the background of altered reactivity of the organism was followed by positive changes of clinical and immunological data by as early as the 2-3d days of the postoperative period. The level of antistaphylococcal immunity was preserved after completion of the course of leukotransfusions. It results in complete arrest of the inflammation in the mammary gland, excludes the development of recurrences and various pyo-septic complications. Leukotransfusion is not only a method of substitution therapy but also an effective immune-correcting factor.

Blood Transfusion↗
PubMed1987

[Mixed gel precipitation in the analysis of monoclonal antibodies against determinants of the carcinoembryonic antigen].

Mixed gel precipitation technique was used in the study of 5 monoclonal antibodies (MA) to carcinoembryonic antigen (CEA). The method is based on specific inclusion of MA into the precipitate formed by the antigen and polyclonal antibodies to it. The test-system for the determination of nonspecific cross-reacting antigen (NCA) has demonstrated that MA 2D10 are directed to the determinant, common for CEA and NCA, whereas MA 3C12 and 2G10 give no reaction with NCA. The specificity of MA 192 and 35 correlated with the previously established one. Mixed gel precipitation technique is recommended for primary screening and study of MA specificity to any precipitating antigen.

Animals↗
PubMed1987

[Express evaluation of the severity of the course of lactation mastitis].

The authors consider that quantitative and qualitative characteristics of phagocytosis can be given with the help of lysosomal-cationic test (LCT) at different periods of acute purulent lactation mastitis. LCT gives prognosis of the course of the disease and a reliable estimation of the treatment efficiency.

Blood Bactericidal Activity↗
PubMed1986

[Immunologic status and leukocyte function of patients with suppurative lactational mastitis].

In patients with a severe course of suppurative lactation mastitis there develops a relative deficiency in the cellular and humoral links of immunity. The compensatory activation of factors of nonspecific antiinflammatory resistance of the organism fails to exert a substantial positive effect on the development of the destructive process in these patients. On the basis of the data obtained, in order to improve results of the surgical treatment of patients with suppurative lactation mastitis means of the cellular anti-infection therapy, transfusions of donor leukocyte masses in particular, must be included in the complex of curative measures in the postoperative period.

Antibody Formation↗
PubMed1983

[Choice of incision in purulent lactation mastitis].

The experience with the operative treatment of 500 patients with acute lactation mastitis enabled the authors to elaborate sparing hemioval cuts of the mammary gland for the opening and drainage of abscesses.

Acute Disease↗
PubMed1979

Cross-reactivity of cytotoxic T-lymphocyte antigen-binding receptors immune to antigens of the H-2 system.

Anti-B10 D2 (anti-KbDb) cytotoxic T lymphocytes (CTL) and monospecific anti-Kk and anti-Dd CTL, separated from their mixture in anti-A B10 lymphocytes and concentrated with the absorption-elution technique on the macrophage monolayers of various genotypes, gave rise to cross-lysis of third-party target cells. Anti-B6 R101 (anti-Kb) CTL, which display a cross-lysis of mutant Kbd (M505) and Kba (Hzl) target cells, were separated into two fractions, one of them being able and the other unable to adhere to the cell monolayer of the particular mutant. The fraction of anti-Kb CTL adherent to Kba antigen was isolated by elution from the Hzl cell monolayer. These anti-Kba CTL and CTL eluted from the B6 cell monolayer displayed a considerably higher cytotoxic effect on B6 than on Hzl target cells. This difference was not due to lower sensitivity of Hzl targets to lysis. The findings indicate that anti-Kb CTL are homogeneous in the specificity of their receptors. The H-2 molecule is presumed to bear a single CTL determinant only, which induces a CTL clone or a group of clones homogeneous in specificity but heterogeneous in the affinity of its receptors.

Animals↗
PubMed1979

[Cross reactions in the H-2 system of cytotoxic T-lymphocytes concentrated by the adsorption-elution method on target cell monolayers].

Cytotoxic T-lymphocytes (CTL) obtained by in vivo immunization were enriched by the absorption-elution technique, using the relevant allogeneic target cell (TC) monolayers. After the separation of C57BL anti-A (anti-KkDd) lymphocytes into anti-Kk and anti-Dd subpopulations they displayed cross killing cytotoxic effect on H-2d and H-2kTC, respectively. B10D2 anti-B10 (anti-KbDd) lymphocytes cross reacted to H-2a and H-2q TC. The results are discussed in the light of heterogeneity of CTL clones or their receptors.

Alleles↗
PubMed1979

[Importance of immunotherapy in the management of patients with acute staphylococcal lactation mastitis].

Failure of antibiotic therapy against the background of sharply decreased defensive forces of the organism in the postpartum period made it necessary to perform a comparative clinical evaluation of the effect of homologous and heterologous gamma globulins. It has been established that treatment with these drugs results in normalization of clinical and immunological signs which are retained till the complete recovery of patients.

Acute Disease↗
PubMed1978

[Use of heterologous antistaphylococcal gamma-globulin in treating suppurative mastitis].

The effectiveness of heterologic antistaphylococcal gammaglobulin was studied in the clinic in 67 cases of acute lactogenous mastitis. The activity of the preparation was 200 A. E/ml. The Bezredko method of injection was used--l ml once a day during 5 days. The treatment resulted in the decrease of intoxication, purification of the surgical wound, normalization on non-specific protection factors, rise of antistaphylococcal antitoxin titers and decrease of autosensitization phenomena.

Animals↗
PubMed1977

[Immune lymphocyte inhibition of activation of DNA synthesis in mixed cultures of normal lymphocytes in vitro].

Substitution of normal lymphocytes by immune ones as responding cells in the "one-way" mixed lymphocyte culture (MLC) results in inhibition of the DNA synthesis. This phenomenon is reproduced irrespective of the mouse strains used, immunization method (in vivo or in vitro) and various MLC techniques (macro- or microcultures, the presence of mercaptoethanol in the medium, control variants). Unlike the cytotoxic effect of immune lymphocytes showing a sharp peak on the 8th day after in vivo immunization, inhibition of the DNA synthesis activation in MLC occurred as the second day, and persisted for several weeks after immunization; this inhibition was reproduced on addition of a small fraction (5 to 10%) of immune lymphocytes to normal ones.

Animals↗