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Biomedical subjects

A Tuunainen

Publications and source records attributed to A Tuunainen.

29 records · Page 2Linked to original sources
PubMed1994

Postoperative psychoses in epileptic patients after temporal lobectomy.

INTRODUCTION: Psychosis is the most severe psychiatric complication after epilepsy surgery. PATIENTS AND METHODS: We evaluated postoperatively at 1 year the psychoses of a series of 57 adult patients with intractable epilepsy who underwent temporal lobe surgery. RESULTS: Five patients (8.8%) developed postoperative psychosis. Two (3.5%) of these 5 revealed postictal psychotic episodes in connection with persisting seizures, both of them had had similar episodes even preoperatively. Two patients (3.5%) exhibited a definite and one patient (1.8%) a probable de novo schizophrenia. CONCLUSION: Our findings clearly emphasize the need for careful postoperative psychiatric follow-up for patients with temporal lobectomy.

Adult↗
PubMed1993

Ictal recordings of ambulatory cassette EEG with sphenoidal electrodes in temporal lobe epilepsy: comparison with intensive videomonitoring.

Seventy-three seizures in 18 epilepsy patients were studied by analyzing the ictal findings of 8-channel ambulatory EEG (A/EEG) and adjacent 16-channel intensive videomonitoring (IVM). With IVM and A/EEG analysis, accuracy was excellent for determining the lateralization of seizure progression; whereas at seizure onset and post-ictal slowing, accuracy was poor. No false lateralization was found in A/EEG compared with IVM or lateralization according to patient data, and in seizure lateralization the interpretation of A/EEG was discordant in only 3 seizures with IVM analysis. According to our study, ictal 8-channel A/EEG with sphenoidal electrodes is not suitable for localization of temporal lobe foci, but is reliable for lateralization analysis.

Adult↗
PubMed1990

Efficacy of a 1- to 3-day ambulatory electroencephalogram in recording epileptic seizures.

The duration of an ambulatory electroencephalogram (aEEG) necessary to record epileptic seizures was studied in neurological patients. A total of 2221 aEEG recordings were made for 2035 inpatients. Ambulatory EEG lasting 1 to 8 days (mean, 1.6 days) included seizures or typical undiagnosed symptomatic attacks in 750 recordings (34%), and 266 of them were epileptic in origin. Symptomatic attacks without simultaneous EEG discharges were exhibited in 27% of the epileptic patients. Of the total number of epileptic seizures, 81% were encountered during the first 24 hours, an additional 10% during the next 24 hours, and 7% during the third 24-hour period. Our conclusion was that, in patients exhibiting epileptic seizures during the aEEG recording, the diagnosis will be confirmed by a 2-day recording in the vast majority of the cases.

Adult↗
PubMed1984

Blood glucose and serum insulin responses to breakfast including guar gum and cooked or uncooked milk in type 2 (non-insulin-dependent) diabetic patients.

The post-prandial blood glucose and serum insulin responses to test meals, each including 300 ml fat-free milk taken separately with the meal or premixed before cooking into the meal consisting of oatmeal porridge, were studied in 10 diet-treated Type 2 (non-insulin-dependent) diabetic subjects. The modifying effect of guar gum on the responses was also studied by supplementing both types of test meals with 5 g granulated guar gum taken at the beginning of the meal. The blood glucose response was higher after the meal which contained cooked milk than after the respective meal with milk taken separately. The guar gum supplementation attenuated the blood glucose response after the meals, but the effect was more pronounced after the meal containing cooked milk. Post-prandial serum insulin responses were similar after all test meals. The results suggest that cooking may facilitate the absorption of lactose from milk-containing foods, and that supplementation with guar gum may counteract this response.

Adult↗
PubMedDate not supplied

Postoperative EEG and electrocorticography: relation to clinical outcome in patients with temporal lobe surgery.

To evaluate the role of different EEG methods with respect to postoperative clinical follow-up, 32 non-lesionary epilepsy patients who had undergone temporal lobectomy were studied preoperatively and at 2-week, 3-month, and 1-year postoperative follow-up. Routine, sleep, and sphenoidal EEG recordings as well as intraoperative electrocorticography (ECoG) were made for all patients. At 1-year follow-up, the EEGs with sphenoidal electrodes and with sleep deprivation procedure provided important prognostic information; the appearance of seizures was associated with the presence of interictal epileptiform abnormalities in EEG. In the postresection ECoG, however, epileptiform abnormalities were not associated with clinical outcome or with postoperative epileptiform EEG at 1 year. Routine EEG reliably reflects clinical outcome after temporal lobectomy; with sphenoidal electrodes as well as with sleep deprivation procedure, the diagnostic yield can be further improved.

Adolescent↗