Deafness and vitiligo in an Italian family.
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Biomedical subjects
Publications and source records attributed to A Tosti.
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A significantly high prevalence (41%) of non-organ-specific autoantibodies, tested in immunofluorescence with sera diluted 1:40, is reported in sera from 86 alopecia patients. No correlation was found with extension and duration of the disease, topical treatment with contact agents or response to it. The relevance and significance of these findings, with particular reference to anti-smooth muscle and anti-basal cell layer antibodies, is discussed.
The skin diseases observed in 41 children affected by type-1 diabetes and in 1,273 children unaffected by diabetes were compared to evaluate the dermatoses that are associated to type-1 diabetes. A high prevalence of vitiligo, psoriasis and herpes simplex infections was found in diabetics. These data are confirmed by statistical comparison.
This study was carried out on 83 patients with alopecia areata. Ophthalmological examinations showed lens changes in 65 patients and alterations in the retinal epithelium in 28 patients. The relationships between pigment cells and hair cycle are discussed.
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The authors report a study carried out on 82 patients affected with gonococcal urethritis, in order to investigate the activity of minocyclin in the prevention of postgonococcal urethritis.
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