The aim of our work was to investigate the interrelationships among rapid eye movement (REM) percent, latency, and density and their variations during different nights in an adequate REM-deprivation study. Twenty male subjects slept for 7 consecutive nights in the laboratory: 2 adaptation, 1 base line, 2 deprivation, and 2 recovery. Wilcoxon's test showed a significant increase in REM percent and a decrease in REM latency from base line to recovery nights. REM density on the contrary showed a decrease, possibly due to dilution caused by increased time spent in stage REM. Eye movement activity appears to remain stable after REM deprivation. Furthermore, REM density showed no correlation with other REM sleep measures, while its highly significant correlations across nights make it a reliable and stable descriptor of an individual's sleep pattern. The independence of eye movement activity with respect to other parameters of REM sleep is suggested.

Adolescent↗

PubMed1980

[Importance of continuous control of central venous pressure in the therapy of shock in obstetrics].

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Adult↗

PubMedDate not supplied

Spontaneous resolution of congenital bilateral Brown's syndrome.

We report a case of bilateral Brown's syndrome in a 4-year-old girl. Forced duction testing confirmed the clinical diagnosis. After 7 months we observed a spontaneous resolution in the right eye. The problem in her left eye did not show any significant change over 36 months of follow-up. Various spontaneous resolutions in bilateral cases are reviewed.

Child, Preschool↗

PubMedDate not supplied

Cytomegalovirus infection in two infants with congenital or neonatal solid tumors.

Two infants with fibrosarcoma and rhabdomyosarcoma diagnosed prenatally and at 2 months of age, respectively, and cytomegalovirus (CMV) infection are reported. Concomitant CMV infection was revealed by positive urine culture and/or CMV DNA, and CMV-specific IgM, IgA, and complement-fixing antibodies. The patients, showing very low levels of immune T cells, died at 3 and 8 months of age, respectively. A pathogenic role for CMV in the progression of the tumors is suggested.

Cytomegalovirus Infections↗

PubMedDate not supplied

[Progressive systemic sclerosis associated with anti-myeloperoxidase ANCA vasculitis with renal and cutaneous involvement].

Sclerodema renal crisis is the usual form of presentation of renal disease in systemic sclerosis. We report a woman who at age 63 was given a diagnosis of scleroderma with Raynaud's phenomenon and cutaneous, oesophageal and lung involvement but no evidence of renal disease and no treatment with D-penicillamine. Two years later she developed progressive renal failure, nephrotic range proteinuria, haematuria and the presence of serum MPO-ANCA; she was normotensive. Renal biopsy revealed extracapillary and necrotizing glomerulonephritis and skin biopsy showed leucocytoclastic vasculitis. This clinical picture was compatible with necrotizing vasculitis of the microscopic polyarterits type. After treatment with pulse steroids followed by oral steroids and monthly intravenous cyclophosphamide her renal function stabilised and the serum MPO-ANCA disappeared.

Aged↗

PubMedDate not supplied

[Idiopathic membranous nephropathy in an elderly patient with type 2 diabetes mellitus].

We report an 85 years-old patient with type 2 diabetes mellitus and both clinical and biochemical nephrotic syndrome. The renal biopsy showed membranous nephropathy at stage I-II. There was no evidence of malignancy. The patient was treated with steroids, and two months later the proteinuria had not improved. The objects under discussion are the factors that should lead to suspect the existence of glomerulonephritis, other than diabetic glomerulosclerosis, suggesting the need for kidney biopsy. We also focus on the prognostic and therapeutic relevance, as well as on the common pathogenic aspects.

Adrenal Cortex Hormones↗

PubMedDate not supplied

[Reversible acute renal failure in minimal-change glomerular nephrotic syndrome].

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Acute Kidney Injury↗

PubMedDate not supplied

[Ascites as an unusual manifestation of chronic granulomatous disease in childhood].

Ascites is a late and uncommon symptom of Chronic Granulomatous Disease (CGD) of childhood following liver damage with portal hypertension due to hepatic granulomatosis. The Authors describe two patients with CGD, in whom ascites was the main symptom in the first case and the initial symptom in the second case. Ascites in these cases was not due to liver fibrosis but it was a consequence of primary bacterial peritonitis.

Ascites↗