Biomedical subjects

A Tontis

Publications and source records attributed to A Tontis.

At least 37 records · Page 2Linked to original sources

PubMed1991

[Epitheliogenesis imperfecta in lambs].

In a herd of 23 ewes of the White Alp breed, a congenital epitheliogenesis imperfecta was observed in five twin-births. All lambs originated from the same father. Except in one case, only one of the twins was affected. Characteristic lesions were epidermal defects between the coronary groove and the carpal/tarsal joint, exungulation, and defects in the buccal mucosa (cheeks, palatum durum, tongue). After removal of the ram from breeding, no more abnormalities were observed.

Animals↗

PubMed1990

[Pathology of bovine cardiomyopathy].

Pathological findings from 389 SimmentalxRed Holstein cattle and from 11 Holstein/Friesian cattle with cardiomyopathy (CMP) are described. The average age of affected animals was 34 months; the majority of cases was observed between October and March. The hallmark of the disease was cardiomegaly with ventricular and atrial dilation and hypertrophy, as well as myocardial fibrosis, in part accompanied by myofibrillar degeneration. Striking vascular changes within lung vessels were hypertrophy of arteriolar and venular walls together with luminal stenosis of veins. Marked hepatomegaly was induced by chronic liver congestion with hepatocyte degeneration and fibrosis. Many cases showed chronic, interstitial nephritis. CMP affected crossbred cattle only, which suggests a genetic factor influencing the pathogenesis of this disease by possibly interfering with biochemical and metabolic pathways leading to endothelial damage and extracellular matrix alterations.

Animals↗

PubMed1987

Cutaneous lymphosarcoma of helper/inducer T-cell origin in a calf.

A calf with a lymphoproliferative disease resembling human mycosis fungoides, had multiple, ulcerated skin nodules with enlarged regional lymph nodes. Tumor cells were 10-15 micron in diameter and had round to oval nuclei without indentations. Mitoses were regularly present. Pautrier's microabscesses were in the epidermis, and T-cell areas of regional lymph nodes were infiltrated by neoplastic cells. Demonstration of the T-helper/inducer origin of neoplastic lymphocytes suggested classification in analogy with human mycosis fungoides.

Animals↗

PubMed1987

[Pregnancy toxemia of small ruminants with special reference to pathomorphology].

Pregnancy toxemia (PT) is a metabolic disease which causes significant economic losses in small ruminants, especially sheep. Animals are usually affected in the last few weeks of pregnancy, the uterus contains mostly two or more well developed fetuses. A qualitatively insufficient feeding program together with the significant glucose consumption of the rapidly growing fetuses induces progredient hypoglycemia and ketosis. Other factors like stress and decreased ruminal volume may help trigger the metabolic breakdown. The most prominent macroscopic lesion is the extensive fatty infiltration of the liver. Adrenal cortex and proximal tubular epithelium of the kidney are similarly affected. Focal degenerative changes in contractile and conductory myocardial cells may also occur. The frequency of the disease in the necropsy material from our institute is reviewed over a period of 8 years and pathology and pathogenesis of PT are discussed.

Adrenal Cortex↗

PubMed1986