[Multiple primary neoplasms].
In the years 1980-1987 in the Department of Internal Diseases, Silesian Medical Academy in Katowice 32 patients were observed with multiple malignant neoplasms of various organs. The time from the diagnosis of the first neoplasm to the appearance of the second one was from 0 to 168 months (mean 61.8 months). The second neoplasm developed in over half the cases (53.1%) after more than 5 years from the first one. The most frequent first neoplasms were: Hodgkin's disease and breast carcinoma, and the most frequent second neoplasm was colonic carcinoma, gastric carcinoma and endometrial carcinoma. The necessity of prolonged observation of patients with malignant neoplasms during many years is stressed.