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Biomedical subjects

A Tiefenbach

Publications and source records attributed to A Tiefenbach.

32 records · Page 2Linked to original sources
PubMed1979

[Congenital hemolytic anemia].

The cases of 91 patients with congenital hemolytic anemia (H.a.) are reported. The causes of congenital H.a. and the laboratory test by which the diagnosis and precise subclassification of the disease were facilitated are indicated. Emphasis is placed on the therapeutic significance of splenectomy in those patients In whom laboratory tests with a radioactive marker [Cr 51]indicated that splenectomy could have a beneficial effect.

Anemia, Hemolytic, Congenital↗
PubMed1979

[Pelger-Huet anomaly].

A homozygot carrier of a congenital nuclear anomaly of blood cells/Pelger-Huet's anomaly: abnormal segmentation of granulocytic leukocytes) is described. The morphologic analysis of blood samples in 4 family members showed similar Pelger-Huet's anomalies. The phagocytic activity, the "killing test" and the inhibition test of leucocyte migration of the patients neutrophils were in normal ranges.

Child↗
PubMed1977

[Congenital aplastic anemias].

Congenital (constitutional) aplastic anemias in children are relatively rare compared to other diseases but as their outcome is nearly always fatal they are given full attention in pediatric-hematological literature. Although in many patients the number of white cells and thrombocytes as well as of red cells is diminished even in the first phase of the disease (or later in the course of the disease) so that these diseases are really pancytopenias, the term most frequently used to describe these clinical entities is aplastic anemia. The clinical and hematological characteristics of some aplastic anemias (Fanconi's anemia, Blackfan-Diamond's anemia, congenital dyserythropoietic anemia--type I, II, III and IV, etc.) are described. After considering the possible pathomechanisms which bring about aplastic anemia (pancytopenia), information is given about the method of treatment and prognostic prospects with reference to cases treated by the authors.

Anemia, Aplastic↗
PubMed1976

[Results in the treatment of acute lymphoblastic and acute myeloblastic leukemia in children (using Pinkel's and Clarkson's schedules)].

At the Center for the study and treatment of leukemia in childhood (Ward of Hematology, Department of Pediatrics Salata Zagreb) children with acute leukemia are treated by a combined therapy consisting of corticosteroids, chemotherapeutic agents and subjected simultaneously to radiotherapy. The authors present the results achieved in 40 children with acute leukemia (during the period from March 31, 1973 to March 31, 1975.) randomly distributed into three groups. Each group was treated according to a different protocol (using Pinkel's modified scheme for ALL and that of Clarkson for AML), with or without profilactic irradiation of the CNS.

Antineoplastic Agents↗