Biomedical subjects
A Thompson
Publications and source records attributed to A Thompson.
Protein Quality in seed meals of Phaseolus vulgaris and heat-stable factors affecting the utilisation of protein.
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Postmortem stability of somatostatin-like immunoreactivity in mouse brain under conditions simulating handling of human autopsy material.
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Anterior to posterior variations in the concentration of somatostatin-like immunoreactivity in human basal ganglia.
Serial coronal sections were cut from frozen right cerebral hemispheres from five normal human brains. From each section samples of caudate nucleus, putamen, internal and external globus pallidus and substantia nigra were removed. Sampling was such that the entire structure was removed from each slice. The concentration of somatostatin-like immunoreactivity, expressed as units per mg protein, was found to vary between nuclei, and to vary along the anterior to posterior axis of some nuclei. Highest concentrations were found in the caudate nucleus, with the head and tail containing greater amounts than the body. The high concentrations in the head of the caudate may be due to contamination of samples of this region with adjacent nucleus accumbens. In a separate series of cases, the nucleus accumbens was shown to be considerably higher concentrations of somatostatin-like immunoreactivity than the head of the caudate. Concentrations in the putamen tended to decrease along the anterior to posterior axis. In the external globus pallidus, levels of somatostatin-like immunoreactivity showed the most striking changes along the anterior to posterior axis, rising 2.5 fold in the first three samples, and then falling 4 fold in the more posterior sections. The internal globus pallidus had generally lower concentrations, and these varied in a pattern opposite to that in the external globus pallidus. Levels in the substantia nigra were low compared to those in caudate and putamen.
A digital variable persistence oscilloscope for gamma cameras.
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The first New Zealand isolation of Leptospira interrogans serovar australis.
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Practical nursing: applying the nursing process to the care of the mentally handicapped.
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Practical nursing: the nursing process. 1. Its value for special hospital patients.
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Chronic middle ear disease and auditory perceptual deficits: is there a link?
Data are presented indicating a correlation between chronic recurrent otitis media of early childhood and in increased likelihood of subsequent auditory processing deficits in a group of children referred for evaluation of impaired learning. Helpful appendices are added for a better understanding a central auditory processing skills.
Retention of fluoride from diets containing materials produced during aluminium smelting.
1. Using male rats, the availability of fluoride from five by products of the aluminium smelting industry was tested. This was done by considering the balance between fluoride administered in controlled diets and the total fluoride content of waste products eliminated over an experimental period of 1 week. 2. Results indicated that yields of available fluoride expressed as percentage weight of original material were cryolite (Na3ALF6), 45.9%; sodium fluoride (NaF), 41.7%; aluminium fluoride (AFL3.H20), 9.1%; mist eliminator grid solids (with CaF2), 9.4%; reclaimed alumina with adsorbed F, 0.27%. 3. Of the various tissues analysed for fluoride content, only the kidney and femur showed any significant correlation with the amounts of fluoride absorbed or retained.
English schoolchildren and illegal drugs. II. Changes over one year.
Part I of this paper described levels of familiarity with drugs of fifth form pupils in 29 schools in England. In Part II, changes in reported levels of drug use over 1 year are described in two sets of pupils. First, changes in drug use reported between a 1973 forth form group and a matched fifth form group from the same schools 1 year later (follow-up study); and second, differences in reported levels of use between the 1973 fourth form and a matched group of 1974 fourth forms from the same schools (trend study). It is concluded that there was no evidence of any substantial general increase or decrease in familiarity with drugs in the schools studied during the 1-year period of study.
The quality of protein in the digesta entering the small intestine of sheep [proceedings].
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The effect of diphtheria toxin on pulsating rabbit, guinea pig, human and rat heart cell cultures.
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Immunoglobulin-bearing cells in giardiasis.
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English schoolchildren and illegal drugs. I. Levels of familiarity with drugs.
Questionnaires were given to groups of fifteen and sixteen-year-old students in 29 schools in various parts of England, and their reported familiarity with illegal drugs is presented here: those students who have no drug-using acquaintances, those who have such acquaintances but have never been offered an illegal drug, those who have had offers and rejected them all, and those who have ever accepted an offer are distinguished. Levels of acceptance of illegal drugs, which averaged 10.5% across the schools sampled, are compared with levels found in other English surveys. It is concluded that levels of familiarity with illegal drugs varies so much from school to school that attempts to establish a national average figure would not be useful for predicting levels of familiarity in any particular school. Part II of this paper, forthcoming, will discuss changes over the 1-year period 1973-1974.
Rat lymphocyte differentiation antigens detected by rabbit antiserum to thymocytes and leukaemic cells.
The lymphocyte differentiation antigens detected by rabbit antisera to rat thymocytes and leukaemic cells have been investigated. Thy-1 was the only such antigen detected by the anti-thymocyte serum, which was predominately directed to two xenoantigenic determinants rather than the Thy-1.1 determinant on this molecule. Two additional antigens were recognized by the anti-leukaemia serum. One of these was found on thymocytes and peripheral lymphocytes, but only on 1 per cent of bone marrow cells. The other was found not only on lymphocytes, but also on the nucleated myeloid and erythroid cells of bone marrow.
Renal and cardiac complications of drug abuse.
The case is presented of a young man who, after prolonged intravenous narcotic administration, developed subacute bacterial endocarditis involving the aortic valve, and rapidly progressive glomerulonephritis. After treatment of and recovery from renal failure, persistent proteinuria was shown to be caused by focal glomerulosclerosis. The association of these lesions with "mainlining" is reviewed.