Search PubMed⌕ Search

Biomedical subjects

A Tennstedt

Publications and source records attributed to A Tennstedt.

At least 37 records · Page 2Linked to original sources

[Malformations of the urogenital system in autopsy material of children].

As a result of the autopsy reports of the Pathological Institute of Mühlhausen in the twenty-year-period from 1960 to 1979 there were 6.4% (n = 293) malformations of the urogenital system among 4,561 autopsies of still-born and live-born children up to their 16th year of age. Besides anomalies of the genital system, anomalies of the lower urinary tract, cystic kidneys, anomalies of kidney forms and dystopia as well as kidney agenesis were most commonly observed. The malformations were classified and discussed according to nature, combinations and sex differences, importance for mortality as well as with respect to territorial and time distribution.

Abnormalities, Multiple↗

[Abnormalities of the skeletal system in autopsied children].

As a result of the autopsy reports of the Pathological Institute of Mühlhausen in the twenty-year period from 1960 to 1979 there were 4.8% (n = 180) malformations of the skeletal system among 4,561 autopsies of still-born and live-born children up to their 16th year of age. Club-foot was the most frequent malformation followed, with decreasing frequency, by inborn anomalies of the spinal column, syndactylia and polvdactylia as well as dysmelia. The malformations were classified and discussed according to nature, combinations and sex differences as well as with respect to territorial and time distribution.

Adolescent↗

[Abnormalities of the digestive system in autopsy material of children].

As a result of the autopsy reports of the Pathological Institute of M uhlhausen in a twenty-year-period from 1960 to 1979 there were 4.8 per cent (n = 219) malformations of the digestive tract among the 4,561 autopsies of stillborn children and live-born ones up to their 16th year of age. Lip, jaw and plate clefts, defects of diaphragm as well as oesophagus atresia and stenosis predominate among the various malformations. The malformations were classified and discussed according to nature, combinations, and sex differences as well as with respect to importance for mortality, territorial and time distribution.

Abnormalities, Multiple↗

Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's Disease.

The nucleus basalis of Meynert, the major source of cholinergic innervation of the cerebral cortex, was morphometrically investigated in 58 cases of neuropsychiatric disorders and compared to 14 controls. The results demonstrate a loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease (70%), paralysis agitans (77%), and Korsakoff's disease (47%) but no marked reduction of neurons in postencephalitic parkinsonism, Huntington's disease, chronic alcoholism without dementia, schizophrenia and infantile brain damage. Neurons of the three subdivisions of the nucleus basalis of Meynert (the nucleus septi medialis, the nucleus of the diagonal band of Broca and the nucleus basalis Meynert neurons in the substantia innominata) may be affected in a different manner in different patients within a single group homogeneous with respect to the usual clinical and neuropathological diagnostic criteria. Cell loss in the basal forebrain is restricted to the large neurons of the nucleus basalis, the immediately adjacent neurons of the globus pallidus externus not being affected. The selective degeneration of these neurons provides the morphological correlate of the cortical cholinergic deficiency in these neuropathological conditions. The degeneration of this discrete cholinergic neuronal population in several disorders of higher cortical function is probably directly related to the progressive deterioration of memory and cognitive processes in affected patients.

Alcohol Amnestic Disorder↗

[Psychiatric disorders and growth of brain tumors].

In 49 of 365 clinical and patho-anatomical intracranial tumour cases the tumours were indicated in the anamnesis only by mental disturbances before acute signs of brain pressure appeared. With reference to the relations between the psychopathological syndromes and the types of locations of tumours attention is drawn to factors that may complicate the early detection of tumours.

Adolescent↗

[Malformations of the heart and vascular system in autopsy material of children].

As a result of the autopsy reports of a twenty-year-period from 1960 to 1979 there were 7.1% (n = 324) malformations of the heart and vascular system among 4,561 autopsies of still-born children and live-born ones up to their 16th years of age. Septal defects of the heart are most commonly observed. The malformations were classified and discussed according to nature, combinations and sex differences as well as with respect to importance for mortality, territorial and time distribution.

Adolescent↗

[Atypical symptoms in brain tumour cases. A contribution to their topography (author's transl)].

By autopsy 38 brain tumour cases out of 207 (22.5%) showed atypical, i.e., psychical symptoms and were clinically found to be brain-organic syndromes. These changes most frequently occurred with glioblastomas and meningiomas; but principally they were found with all tumour types. All the tumours destroyed, respectively, touched parts of the limbic system. Emotional and menestic troubles emerged in these cases. It is suggested than an injury of the limbic system is responsible for an exclusive or prevailing psychical symptomatology.

Adolescent↗

[Central nervous system malformations in autopsy material].

As a result of the autopsy reports of a twenty-year-period from 1960 to 1979 there were 5.5 per cent (n = 251) malformations of the central nervous system among the 4561 autopsies of still-born children and live-born ones up to their 16th year of age. Hydrocephalus predominates followed by disturbances of migration and dysraphias in head and spinal region. The malformations were classified and discussed according to nature, combinations and sex differences as well as with respect to importance for mortality, territorial and time distribution.

Adolescent↗

[The asynchronous course of aging processes in the formation of hippocampus].

In the way of quantitative investigations of nerve cells and neuroglia in g. parahippocampalis and following analysis of measuring dates by multivariat variance- and discriminance-analysis was demonstrated that aging process in ammonite formation can be described on the base of cells only in sector subiculum.

Aged↗

[Meningoencephalitis in Behçet's disease--review and clinical-morphological case report].

The paper describes the neuropathological findings in the seven-year case history of a male patient who died at the age of 29 of Behçet's disease with initial iridocyclitis and neurological complications. In the author's opinion, the presence of any one of the three cardinal symptoms of the muco-cutaneo-ocular syndrome and its manifestation on the CNS is sufficient to suppose Behçet's disease. Affectation of the eye is a significant and usually the first symptom. The case history and the typical morphological findings give rise to the assumption of a special ophthalmomeningoencephalic variety of Behçet's disease.

Adult↗

[Contribution to the Louis-Bar syndrome (ataxia telangiectasia) (author's transl)].

An autopsy case report of a Louis-Bar syndrome (Ataxia telangiectasia) is given on a 9 year-old boy who was ill for 7 years. The Louis-Bar syndrome mostly is a hereditary familial disease transmitted by an autosomal recessive gene. We are considering the syndrome as a special form of hereditary ataxias which is morphologically belonging to the systematic atrophies of the cerebellum and, above all, combined with oculo-cutaneous telangiectasia and an immunopathy. As a peculiarity the present case exhibited the existence of generalized angiectasia (cerebellum, meninges, dura mater, epiphysis, skin, eyes, lungs, spleen, kidney).

Adolescent↗

[Therapy and course of alcoholic delirium].

During the past ten years, treatment of delirium alcoholicum was almost exclusively by means of chlormethiazol (distraneurin), an agent which has sedative, hypnotic, and antiepileptic effects. A total of 111 deliriants with single and multiple deliria were subjected to 151 treatments. In the majority of cases the state of delirium was overcome after three days of specific treatment. The case histories of three patients, where the course of disease was extremely severe and additionally complicated by secondary diseases and who died during treatment (the percentage being 0.7% relative to 151 cases of treatment), are discussed in detail. In the case of severe states of delirium accompanied by repsiratory diseases it is necessary that the patient receiving specific treatment be supplied with additional amounts of oxygen because distraneurin, like other sedatives, trends to reduce the utilization of oxygen under certain conditions. The majority of deliriants were in their third to fourth decades of life. Accordingly, our patients were younger than those included in the reports presented by other authors. Also discussed by the present authors are attacks accompanying the state of delirium as well as concomitant diseases complicating the clinical picture and adverse effects of alcohol on the nervous system.

Adult↗

[Sjögren-Larsson syndrome].

The observations made on a 27-year-old patient with ichthyosis, debility, psychoinfantilism, and Little's syndrome are reported. Clinically, the condition of the skin is similar to that associated with ichthyosis vulgaris. Histologically, however, the picture is largely that of ichthyosis congenita, the condition being even more pronounced than that of ichthyosis congenita mitis. This particular case may be placed within the class of transitional forms of hereditary ichthyoses, and it may thus be proved that the Sjögren-Larsson syndrome also has its 'formes de passage'. In the etiological determination of oligophrenias and infantile cerebral motor disorders it is always necessary to give attention to the probable presence of ichthyosiform conditions of the skin.

Adult↗

[Clinical and pathol-anatomic findings in corpus callosum deficiency, enlarged cavum septi pellucidi, and septal defect].

A comparison is made of the pathological changes of the median line structures such as corpus deficiency, enlarged cavum septi pellucidi (Csp.) and septal defects in 10,457 pneumo-encephalography (PEG) examinations of neurological and psychiatric patients, and in 11,016 general autopsy cases. Clinical peculiarities in corpus deficiency and other development anomalies of the median line structures are discussed along with case reports. A predominance of the male sex in cases of enlarged Csp. together with frequent combinations with neurological and psychiatric illness were noticeable, particularly oligophrenia, behavioral disorders, epilepsy and cerebral tumours. Thus, certain inferiority of the dysrhaphic mutation of the central organ can be assumed.

Adolescent↗