[Treatment of chronic alcoholics by L-glutamic acid mono-amide (apropos of 36 cases)].
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Biomedical subjects
Publications and source records attributed to A Tatossian.
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The authors report the results of an open trial which aims at specifying the clinical profile of responders to carbamazepine among a population of twenty patients aged from fifteen to seventy, suffering from endogenous, schizophrenic, affective psychoses and paranoid states according to the criteria of the ICD 9. The trial points out a proof of Kishimoto's criteria and a preferential acting of the molecule on schizo-affective psychoses and mixed affective states. The results are interpreted according to psychopathological concepts from the Vienna school that highlight the clinical profile of the responders.
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We have applied, with necessary modifications, life-events methodology, to the study of nature and temporal distribution of life-events occurring in 120 chronic alcoholics. Total number and distribution of life events undergo some variations with age, sex, ethnic group and socio-professional level in chronic alcoholics. We have specially analysed the temporal curve of life events before, during and after the year of beginning alcohol abuse. Frequency of life events dramatically rises during this year and remains abnormally high in the five following years. These data have some meaning for pathogenesis and behavioral consequences of chronic alcoholism.