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Biomedical subjects

A Tampieri

Publications and source records attributed to A Tampieri.

45 records · Page 3Linked to original sources
PubMed1982

[Determination of IgM anti-Toxoplasma gondii antibodies with the immunoenzymatic (IE) method].

The immunoenzymatic method for the research of specific IgM antibodies anti-Toxoplasma gondii is compared to the traditional methods of dosage: absorption of the IgG on staphylococcus and depolymerization of the IgM with 2-mercaptoethanol. The sensitivity and specificity of this method have been analyzed on a sample of 193 serums in order to consider the probabilities of false positive and negative reactions. The simplicity of method and the possibility of expressing values as reciprocal of the maximum dilution make this an elected method for the research of specific IgM. The reduced quantity of serum necessary in carrying out the test represents such a prerogative as to make this method particularly fit for researches on new-born babies.

Antibodies↗
PubMed1975

[Determination of the normal limits of various biochemical parameters in a homogenous sub-population].

Within the limits of a program of preventive medicine for the people in working age we have gived started to a proceeding of methods' standardization and definition of the limits of the "normal" variability of any biochemicals parameters. The research, beginned how quality control (day to day control, between batch control, inter-laboratory control) for the instrumentation in use (Autoanalyzer SMA 12/60) is continued defining for 12 bio-chemical constants the normal bounds of the variability in relation with sex and age of the individual subjects and this in prevision of an enlargement of those bounds with the view of the preventing in the local people.

Aspartate Aminotransferases↗
PubMedDate not supplied

[Intrahepatic cholestasis in pregnancy: incidence, clinical course, complications].

From January 1st, 1984 to December 31st, 1988 67 cases of cholestasis during pregnancy (frequency rate 0.7%) have been reviewed. In the 79% of the cases cholestasis arose after the 32nd week. Preterm deliveries were 19.5% and cesarean sections were 19.4%. Perinatal mortality was 30%. Pregnancy complicated by cholestasis is a high risk problem in obstetrics. An attempt to show a clinical management is exposed.

Adult↗
PubMedDate not supplied

Influence of glycyrrhizin on the evolution and respiration of Ehrlich ascites tumour cells.

It has been demonstrated that 18 alpha-glycyrrhetinic acid, 18 beta-glycyrrhetinic acid and glycyrrhizin effectively inhibit the inception and growth of skin tumours. Moreover, glycyrrhizin and its aglycone act on the growth and differentiation of mouse melanoma cells in culture. In this study we investigated the effect of glycyrrhizin, 18 alpha- and 18 beta-glycyrrhetinic acids on the evolution of Ehrlich ascites tumour in mice. A prolonged glycyrrhizin treatment proved to be effective in modifying the animals' survival pattern.

Animals↗
PubMedDate not supplied

Influence of antimalarials chloroquine, quinine, primaquine and mepacrine on the evolution of Ehrlich ascites tumour.

Substances like imidazoles, benzimidazoles and also quinolines, whose chemical structure includes a heterocyclic nitrogen, are known to interfere with the microsomal oxidation and, in some cases, with the metabolism of drugs. Since chloroquine and primaquine exert this effect in vivo and in vitro, we studied the influence of other antimalarials (quinine and mepacrine) in mice with induced Ehrlich ascites tumour (EAT) to find out whether variations in oxygen consumption affected the course of the disease. In vitro data, obtained by a polarographic technique, indicate that primaquine and, in particular, mepacrine increase EAT-cell oxygen consumption, while in vivo data, obtained in mice injected with an inoculum of about 1 x 10(6) tumour cells per mouse, show that both drugs, but notably mepacrine, accelerate tumour growth, as monitored by Cox's statistical method for body weight, and lead to earlier death. In cases of existing neoplasia, therefore, the potentially toxic effects of certain antimalarials must be borne in mind.

Animals↗