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Biomedical subjects

A Tada

Publications and source records attributed to A Tada.

At least 145 records · Page 8Linked to original sources

[Measurement volume of intracranial hematoma by computed tomography (author's transl)].

On hypertensive intracranial hematoma, the hematoma volume on CT scan was measured by Delta scan 50 with MAP-program. 1) In each slice of the hematoma, high density mass lesion, the area was measured by joy stick on viewing console, and relationship with print out data, area above 40 CT values was good. 2) Correction of partial volume effect, especially of high of hematoma in the 10 mm scan slice was done with each mean CT values of the hematoma, and central CT values of that. For correction of partial volume effect, hematoma volume was decreased compared with the volume measured by MAP area measurement only, but in phantom study, corrective hematoma volume has shown high accuracy. 3) In comparison of corrective hematoma volume with maximum length of hematoma, line measurement does not evaluate of hematoma volume proportionaly as large. Though calculated volume by modified Dodge's formula (pi/6 X L X S X slice) has shown good relationship with corrective hematoma volume. Then, in clinical use, measurement of 3 line distance, maximum length, crossed short length, slice thickness contained hematoma was recommended to evaluate actual hematoma volume.

Cerebral Hemorrhage↗

Radioimmunoassay for carcinoembryonic antigen and alpha 1-fetoprotein in the qualitative evaluation of focal hepatic lesions in Japan.

The combined tests of serum alpha 1-fetoprotein (AFP) and carcinoembryonic antigen (CEA) were routinely performed in 210 patients with focal hepatic lesions on a 99mTc-colloid liver scan in order to determine whether these could provide more useful information that AFP test alone in the qualitative evaluation of focal hepatic lesions. The predictive value of hepatoma with positive AFP alone remained 80%. However, when the negative CEA was combined with positive AFP, the predictive value of hepatoma (91%) with both was greatly increased. On the other hand, the predictive value of metastatic liver cancer with positive CEA showed 92%. The combined test of AFP and CEA may be useful for preserving high predictive values of hepatoma and metastatic liver disease.

Carcinoembryonic Antigen↗

Studies on the neutralization of herpes simplex virus. X. Demonstration of complement-requiring neutralizing (CRN) and slow-reacting CRN (s-CRN) antibodies in late IgG.

A sample of late IgG from a rabbit hyperimmunized with herpes simplex virus was analyzed for neutralizing (N) and complement-requiring neutralizing (CRN) antibodies. In a usual endpoint test, N and CRN titers were 1: 40 and 1: 160, respectively, but when virus-IgG mixtures were incubated at 0 C overnight before addition of complement (C), an endpoint of 1:1280 was obtained. Virus sensitized at 0 C overnight required more C for inactivation than did sensitized virus formed earlier. Sensitization kinetic curve experiments employing a proper initial virus concentration, which permitted differentiation of sensitized viruses requiring different amounts of C, indicated that formation of sensitized virus detectable only with a relatively large amount of C proceeded slowly at IgG dilutions where the ordinary CRN antibody requiring a smaller amount of C was negligible. The results strongly suggested that the IgG sample contained slow-reacting CRN (s-CRN) antibody in excess of the hitherto known CRN antibody. As to the mechanism of formation of s-CRN complexes, experiments failed to prove the occurrence of complexes initially insensitive to C, and it appears more likely that s-CRN antibody has a comparatively low avidity for virus.

Animals↗

[Ossification of the posterior longitudinal spinal ligament--comparative studies with computerized tomography (author's transl)].

Ossification of the posterior longitudinal spinal ligament (OPLL) was characterized by calcified longitudinal band along the posterior margin of vertebrae, but it has not been possible to know how the cord is compressed within the narrowed spinal canal. Our neuroradiological studies based on CT-view of the 15 cases of OPLL suffering from various degree of myelopathy revealed: 1) Computed tomography precisely delineated shape of OPLL, which was quite polymorphic, like mushroom, irregular cubic and round. OPLL ranged more than two vertebrae was not uniform, but exhibited different configuration at each level. 2) OPLL at lower cervical and higher thoracic regions was difficult to diagnose by conventional lateral roentgenograms, but CT-scan demonstrated clearly whole extent of OPLL. 3) obliteration ratio of the affected spinal canal was calculated on CT-scan. Cases showing severe myelopathy, such as quadriparesis and neurogenic bladder, presented spinal canal stenosis of more than 30%. Spondylosis were concomittant roentgenographic findings on 13 cases of OPLL (87%). However, spondylotic changes responsible to the myelopathy were seen on only three cases. In these case, the obliteration ratio by ossificated ligament was lower than 26%. On conclusion, computed tomographic views of OPLL gave us more detailed information about the stenotic spinal canal and found to be essential examination when considering operative intervention.

Aged↗

Neuroradiology of ossification of the posterior longitudinal spinal ligament. Comparative studies with computer tomography.

Comparative neuroradiologic studies of the posterior longitudinal spinal ligament were performed in 15 cases showing myelopathy. On visualizing the ossified foci CT scan was found to be superior to the conventional roentgenograms, and detailed evaluation of the constricted spinal canal with related neurologic deficits became possible. CT analysis must be performed to differentiate spondylotic myelopathy, which is essential when considering operative intervention.

Humans↗