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Biomedical subjects

A Stevenaert

Publications and source records attributed to A Stevenaert.

At least 91 records · Page 5Linked to original sources
PubMed1981

[Immediate effects of intravenous acetazolamide on intracranial pressure (author's transl)].

Nineteen patients with hydrocephalus or head injury were subjected to a continuous intraventricular pressure monitoring and received acetazolamide. Seven mg per Kg body-weight were infused intravenously in one minute. Three patterns of reactions were recorded: 1. a sharp and large rise in cerebrospinal fluid pressure 2. a moderate rise 3. no significant change in C.S.F. pressure. The mechanisms of these responses are investigated: metabolic CO2, which is normally converted rapidly to HCO3- through mediation of carbonic anhydrase within erythrocytes, builds up to produce an immediate effect of cerebral vasodilatation and increases C.S.F. pressure of patients with disturbed compensatory mechanisms. Intravenous acetazolamide may be used as a functional test in patients with ventricular enlargement and normal intracranial pressure. This technique provides useful data about the remaining compensatory capacity for further increases in intracranial volume.

Acetazolamide↗
PubMed1980

Compared effects of enflurane and of halothane on the intracranial pressure and the cerebral perfusion pressure in the dog.

In this study, we compare the values of the systemic arterial pressure (S.A.P.), of the intracranial pressure (I.C.P.) and of the cerebral perfusion pressure (C.P.P.) -- (C.P.P. = P.A.S. -- I.C.P.) -- in the anesthetized dog, artificially ventilated, before and after vaporization with two halogenated anesthetics, enflurane and halothane at different concentrations. The measures were made in a group of ten dogs in normoventilation and intracranial normotension conditions, in one hypercapnic dog with intracranial hypertension, and in four dogs after injection of sodium laurylsulfate in the internal carotide to induce cerebral edema. In normocapnic dogs, enflurane and halothane increase the I.C.P., decrease the S.A.P. and the C.P.P. Under enflurane 0.5%, the I.C.P., the S.A.P., and the C.P.P. show no significant variations. The increase in I.C.P. is due to the cerebral vasodilator effect of the anesthetics. At equal concentrations, halothane is more hypotensive than enflurane, and the changes in C.P.P. induced by both anesthetics depend more on the variations in S.A.P. than on the variations in I.C.P. In the hypercapnic dog, the vaporization of enflurane and of halothane further enhance the increase in I.C.P., since the vasodilator effect of the anesthetics is added to that of hypercapnia. The S.A.P. and the C.P.P. drop in relation to the concentrations of vaporization used. After sodium laurylsulfate, the administration of enflurane and halothane is accompanied by a drop in S.A.P. and in C.P.P. In this group, the decrease in I.C.P. recorded in two thirds of the cases can be explained by the hypotensive effect of the anesthetics which decreased the hydrostatic pressure in the cerebral vascular bed, a maintenance element of the edema.

Anesthesia, Inhalation↗
PubMed1980

[Traumatic rupture of the medulla with subarachnoid-pleural fistula (author's transl)].

A case of total dural and spinal cord disruption at level T2 in a 23 month-old female is presented. The authors emphasized the absence of spinal shock in this young child. Spine X-ray examination failed to reveal any abnormality. X-ray films of the chest demonstrated fluid in the right pleural space and mediastinum associated with a subarachnoid-pleural fistula. The possible mechanisms responsible for the spinal cord disruption and the absence of spinal shock are discussed.

Arachnoid↗
PubMed1978

[Post-traumatic arteriovenious fistula of the posterior fossa (author's transl)].

The authors report a case of post-traumatic arterioveinous fistula of the dura-mater associated with an extradural hematoma of the posterior fossa. The traumatic nature of the lesion is confirmed by the presence of an occipital fracture facing the fistule responsable for the extradural hematoma. The authors have found on similar case citied in the literature (11).

Arteriovenous Fistula↗
PubMed1976

[Radioisotopic methods for studying cerebrospinal fluid shunts].

The article presents a general and critical review of the radio-isotopic methods for assessing the function of the surgical shunts of cerebrospinal fluid (CSF). The radio-isotope cisternography may indirectly demonstrate the function of the shunt by the postoperative modification of the eventual ventricular reflux and of the permeability of the subarachnoid spaces on the cerebral convexity. The methods of direct ventricular injection of the indicator permit a more direct assessment of the drainage, as based on a scintigraphy, or on the quantitative study of the cephalic radio-activity, or on the demonstration of radio-activityon a target-organ. The direct injection of a highly diffusible indicator in the valve allows a quantitative measurement of the flow of CSF in the shunt and brings morphological arguments for the localization of the eventual occlusion. The technical aspects of the latter method are critically discussed and illustrated by personal results.

Catheterization↗
PubMed1975

CSF scanning in achondroplastic children with cranial enlargement.

This paper reports on an 18-month-old achondroplastic child with dilated lateral ventricles. Results of a cisternographic investigation were normal. No shunting procedure was carried out, and subsequent clinical progress was satisfactory. Some patho-physiological aspects of achondroplastic dysgenesis are discussed.

Achondroplasia↗