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Biomedical subjects

A Steg

Publications and source records attributed to A Steg.

At least 127 records · Page 7Linked to original sources
PubMed1984

[Sarcoma of the bladder in adults].

The authors report five cases of sarcoma of the bladder and make a distinction between homotypical and heterotypical sarcomas and lymphosarcomas presenting specific therapeutical problems. The prognosis is severe because of very frequent local relapse. They recommend disregard of the invasion of the muscular wall, and the performance of total cystectomy following a positive histological diagnosis. In their view, this is the basis for the treatment of sarcomas.

Aged↗
PubMed1984

Lymphography and percutaneous fine needle node aspiration biopsy in the staging of bladder carcinoma.

We studied 56 patients with infiltrating bladder tumor by pedal lymphography and percutaneous fine needle node aspiration biopsy on an outpatient basis. Of 54 evaluable patients 35 (65 per cent) had a positive lymphangiogram. Adequate material for biopsy was obtained in 81 per cent of the patients. Of 15 patients with normal lymphography none had a positive aspiration, whereas 11 (32 per cent) of those with a positive lymphangiogram had a positive biopsy. The high rate of positive lymphography with negative biopsy is attributed to inflammatory changes due to previous transurethral resection of the tumor. Radical cystectomy was done in 38 patients. There were 28 negative aspirations that correlated with 21 negative lymphadenectomies and 4 positive aspirations that correlated with 4 positive lymphadenectomies. There was no mortality and morbidity was mild. Lymphography with fine needle percutaneous node aspiration biopsy has a role in the preoperative staging of bladder carcinoma.

Biopsy, Needle↗
PubMed1984

[Treatment of prostatic cancer with an LH-RH agonist: the D Trp6 LH-RH. Preliminary results in 30 cases].

Thirty patients with advanced prostatic cancers (8 stage C, and 22 stage D) were treated for at least three months with D Trp6 LH-RH, a powerful LH-RH agonist. In all the cases in which the testosterone levels had been normal before treatment, the treatment led to a decline to the levels observed after castration. In seven cases, the drop was preceded by a rise in the first few days of treatment. Twenty two patients reacted favorably to the "medical castration" resulting from LH-RH agonists (11 improved and 11 remained stable). The improvements were mainly noted in patients who had not undergone previous treatment. Four deaths were registered in patients already at an advanced stage. Two of these patients presented with visceral metastases in circumstances such that a sudden deterioration due to the agonists cannot be excluded.

Aged↗
PubMed1984

Lymphography and percutaneous fine needle node aspiration biopsy in the staging of bladder carcinoma.

Forty-two patients with infiltrating bladder tumor were submitted to pedal lymphography with percutaneous fine needle node aspiration biopsy on an out patient basis. Of 41 evaluable patients, 59% had a positive lymphangiogram. Adequate material was obtained in 81% of the patients. Of 12 patients with a normal lymphography, none had a positive aspiration whereas 40% of the positive lymphangiograms correlated with a positive aspiration. The high rate of positive lymphangiogram negative aspirate is attributed to inflammatory changes due to previous TUR of the tumor. Twenty-one patients were submitted to radical cystectomy: 12 negative aspirations correlated with 11 negative lymphadenectomies, and 4 positive aspirations with 4 positive lymphadenectomies. There was no mortality and only mild morbidity in this series. Lymphography with fine needle percutaneous node aspiration biopsy has a role in the pre-operative staging of bladder carcinoma. Positive pelvic wall lymph nodes upgrade bladder carcinoma from a local to a systemic disease that is no longer amenable to any form of local treatment. Nodal assessment is therefore critical to treatment planning in order to spare the N+ patients unnecessary radical surgery. Pelvic lymph nodes have been evaluated, in the past, radiologically by bipedal lymphography or C.A.T. scanning. The high false positive and negative rates of these procedures (Benson et al., 1981; Boccon-Gibod et al., 1982) preclude their routine use (Correa 1982; Walsh et al., 1980).(ABSTRACT TRUNCATED AT 250 WORDS)

Biopsy, Needle↗
PubMed1984

[Monohydrate and dihydrate oxalic lithiasis. Calculi, their macroscopic structure (radiographic and therapeutic impact). Calciuria and oxaluria].

Calculi of pure calcium oxalate monohydroxide are hard, polish, dark brown stones, of a very tenuous crystalline structure. On the contrary, calculi of pure bihydroxide oxalate are clear irregular stones with a spiky surface. They are more friable and less hard than monohydroxide oxalate stones. Monohydroxide oxalate stones radiologically are regular and homogeneous, whereas bihydroxide oxalate stones have an irregular aspect. Monohydroxide oxalic lithiasis is less frequent than bihydroxide oxalic lithiasis. The proportion of monohydroxide lithiasis is the same in men and women whereas bihydroxide lithiasis is more frequent in men. Of a biologic point of view, in monohydroxide lithiasis, calciuria and oxaluria are often normal while proportion of hypercalciuria and hyperoxaluria is more important in bihydroxide lithiasis. Evolutivity is clearly inferior in monohydroxide lithiasis than in bihydroxide lithiasis.

Adult↗
PubMed1984

[Urogenital complications of abdominoperineal resection of the rectum for cancer].

While operative traumas of the excretory tract are rare, mictional and sexual sequelae often complicate rectal resections for cancer. Although relatively rare, mictional disorders, which mainly affect males, are as often neurogenic as obstructive, and are, in that event, frequently due to iatrogenic urethral stenoses. The neurogenic disorders require an extremely sensitive semiological analysis before contemplating the slightest procedure on the prostate, which may provoke definitive urinary incontinence. Retrograde ejaculation and impotence are frequent, and the latter can be attenuated by a penial prosthesis.

Adult↗
PubMed1983

[Secondary tumors of the kidney].

The authors report twelve cases of secondary kidney tumors. In seven cases, they found antecedents of primary tumors, contrasting with the clinical, urographic and echographic data suggestive of a typical kidney tumor. Only arteriography, when performed, could visualize a hypovascularized tumor. The authors make a distinction between two situations: unilateral kidney tumors, which require total nephectomy, since, in 95% of cases, they are primary growths, and bilateral tumors, which require further exploration, since, in 20% of cases, they are metastatic proliferations.

Adult↗
PubMed1983

[Oxaluria in urinary lithiasis].

The normal value of oxaluria, as determined by gasliquid chromatography, is about 30 mg/24 h. In most cases of renal stone formation (60-70%) the stones are composed of calcium oxalate alone or associated with calcium phosphate. The more evolutive the disease, the higher the oxaluria. The part played by oxaluria in renal stone formation and the need to include its determination in regular examinations of stone formers must be stressed. Treatment of hyperoxaluria is both medicinal and dietetic : control of oxalic acid-rich food intake and reduction of the intestinal absorption of oxalate caused by calcium-deprived diets. The diet must be completed by therapeutic measures aimed at reducing the oxaluria and increasing the urinary factors preventing crystallization.

Diet↗
PubMed1983

[Acid phosphatases].

The authors discuss the pathological value of acid phosphatase measurement. One of its main applications is the diagnosis of prostatic cancer. The emergence of immunological methods of measuring the enzyme, which are more sensitive and more specific, has led to renewed interest as acid phosphatase measurement can now be used in the early diagnosis of prostatic cancer, or at least in the early diagnosis of its extraprostatic extensions.

Acid Phosphatase↗
PubMed1983

[Varicocele and infertility. Facts, uncertainties and hypotheses].

The association between varicocele and male subfertility would seem to be borne out by its incidence in the subfertile male population and the presence of disturbances in spermatogenesis, as well as a description of the different physiopathological mechanisms based on renospermatic venous reflux, and the improvement in the sperm and the obtaining of pregnancy after surgical cure of the reflux. The literature on the subject, and the number of successful case reports, have greatly increased in recent years. There is a tendency to extend the surgical indications to include infraclinical forms of varicocele, and even to perform preventive procedures, against male sterility in varicocele-carrying adolescents. In fact, however, there are wide variations in the estimates of the incidence of varicocele, not only in the general population, but also in the female subfertile population. The relationship between sperm characteristics and fertility is difficult to define. While the presence of renospermatic venous reflux is, in most cases, unquestionable, the exact mechanism or mechanisms of its action are uncertain. The efficacy of surgical management itself is variously assessed, and the methodology employed in many studies is open to question. Only an approach based on fertility epidemiological data and comparative studies employing a methodology which is not open to criticism, will ultimately enable us to define the role of varicocele in male subfertility and the role of surgical management in its treatment.

Animals↗
PubMed1983

The challenging vesicovaginal fistula.

The authors report herein their experience in treating 75 cases of vesicovaginal fistulas. 80% were caused by gynecologic surgery and 20% were of obstetrical origin. The authors favor the transvaginal approach and describe in detail the two technics they recommend. The most commonly used method is the Chassar-Moir procedure. 70% of the patients were cured after one attempt with this procedure, and 93% after two operations. In complicated fistulas (irradiated or extended to the urethra) the Martius procedure was used. In this technic a flap formed from the fat tissue of one of the labia majora is interposed between bladder and vagina. 10 of 11 patients so treated were cured.

Female↗
PubMed1983

[Ureteral stenosis after treatment of uterine cervical cancer: post-radiotherapy fibrosis or neoplastic recurrence?].

Ureteral stricture occurring after radio surgical treatment of uterine cervix cancer does not necessarily express a recurrence of malignancy. The same radiological features may be seen after radiotherapy and then has an incomparably better prognosis. Having in mind the natural history of cancer of cervix we analysed 28 cases of such a tumor, treatment by radiotherapy and surgery. This study led us to defend several discriminating criteria between these 2 conditions. A diagnostic strategy is suggested.

Constriction, Pathologic↗
PubMed1983

[Complete ureteral avulsion. Complication of vaginal delivery of an infant dying in utero during the second trimester of pregnancy].

The authors report a case of complete avulsion of the ureter occurring during the vaginal evacuation of a fetus that had died in utero in the second trimester. This case leads us to discuss the diagnostic and therapeutic measures that should be taken in this kind of situation. At present there are people who wish to increase the number of indications for second trimester terminations of pregnancy. As this is so, we wish to draw attention to a rare but very serious complication of late evacuation of the uterus, namely damage to the ureter.

Abortion, Induced↗
PubMed1982

[Blood group ABO (H) cell surface antigens in bladder tumours invading the chorion. Prognostic value of their determination by immunofluorescence. Retrospective study of one hundred and twenty-five cases].

The authors have studied 125 stage A bladder tumours with a follow-up period of at least 5 years. The ABH cell surface antigens were collected by a double-layer immunofluorescence technique which has already been described. All the cross sections were read by the same pathologist who knew nothing about the clinical developments. The results were divided into 3 groups : (I) all the tumour cells had retained their surface antigens. (II) Only some cells had retained surface antigens. (III) All cells were negative. Study of the development of the 3 groups shows that : in group I, all the patients (11) are alive 5 years later, and only one has presented with a lesion evolving towards infiltration. In group II (32 patients), only 38 p. cent of the patients are still living 5 years later, and 65 p. cent developed towards muscular infiltration. In group III (77 patients), 27 p. cent are alive after 5 years and 80 p. cent have developed towards muscular infiltration. Homogeneous retention of the surface antigens would therefore seem to be a favourable factor in the prognosis, even in the case of a tumour which has already infiltrated the chorion. The significance of the loss of surface antigens is less clear-cut, but is on the whole adverse. The significance would, however, probably be enhanced by study of the mucosa distal from the lesion, and by marking the substances which determine the blood groups.

ABO Blood-Group System↗