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Biomedical subjects

A Steg

Publications and source records attributed to A Steg.

At least 181 records · Page 10Linked to original sources

Cystic changes in adult human kidneys after ureteral obstruction: microdissection studies.

Five kidneys from patients suffering from ureteral obstruction were selected for the study; from each, 100 nephrons and 20 collecting ducts were studied using Darmady's microdissection technique. Whereas three kidneys showed macroscopic cysts, microscopically, all kidneys displayed dilation and diverticulation of the nephrons particularly of the loop of Henlé and of distal convoluted tubules. Some dilatation of the collecting ducts was also noticed.

Aged↗

Renal cysts. I. Current pathogenic approach.

Recent reviews on the genesis of cysts in the adult kidney lead to two major theories: mechanical and toxic. Obstruction indisputably plays a role in determining certain cysts in animals and examination in the human plus certain personal clinical data seems to confirm this. The role of chemical factors in the human has not yet been clearly established, although there is abundant evidence of its occurrence in animals.

Aged↗

Renal cysts in adults. IV. Therapeutic problems.

The study of 1,342 renal cysts gathered from various centres emphasized the great diversity of the therapeutical approach. In this series, 1 patient out of 2 was operated on and 1 out of 6 operations was a nephrectomy. The mortality was 1.2% and complications occurred in 10% of the cases. Arguments in favour of systematic surgery are severely criticized and the risk of failure to recognize a cancer associated with a cyst is very small: when this association was encountered, there were warning signs or symptoms. Percutaneous puncture of the cyst may suffice for diagnosis and treatment of most cases. When surgery is indicated for a cyst as in doubtful diagnosis, symptoms from the swelling or in association with lithiasis, resection of the dome of the cyst is the operation of choice. Considering the extraordinary recovery of the renal parenchyma, the necessity for nephrectomy must be quite exceptional.

Adult↗

Renal cysts. II. Chemical and dynamic study of cystic fluid.

The chemical analysis of the fluid obtained by puncturing 100 simple renal cysts in adults show that the composition of cystic fluid resembles that of interstitial fluid. The chemical balance between cystic fluid and the interstitial space seems to occur passively. Antibiotics which were given orally (amoxycilline, minocycline, rifampicin) do not pass through the wall of a simple cyst. Study of the permeability of the cyst wall did not show any uptake of radioactive hippurate or radium pertechnetate.

Aged↗

Uretero-colic anastomosis by the 'cuff' or 'flap' procedure--Goodwin's modified technique: preliminary report.

Goodwin's procedure of uretero-colic anastomosis under direct vision, performed completely extraperitoneally by the endo-intestinal route marks a considerable progress when compared with the different variations of Coffey's operation. This technique may safely be applied after palliative cystectomy for proliferating bladder cancer if the anastomosis is performed at some distance from the common site of pelvic recurrence, and is provided with a system against back flow. In this regard the 'cuff' process seems quite satisfactory.

Colon↗