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Biomedical subjects

A Staudach

Publications and source records attributed to A Staudach.

82 records · Page 5Linked to original sources
PubMed1977

[Ultrasonic diagnosis in early pregnancy: method, value and problems of differential diagnosis].

According to strictly defined criteria a differential diagnosis between regular pregnancy, imminent abortion, missed abortion, incomplete abortion or hydatidiform mole is attempted using 385 basic ultrasound tests carried out from the 6th to the 16th week of pregnancy. The diagnostic procedure, its pitfalls, their reasons and possibilities of avoidance are discussed. In spite of the wide area of application the positive score of 92% in all basic tests is stressed. Comparing these findings with HCG tests the ultrasound method is clearly superior.

Abortion, Incomplete↗
PubMed1976

[25 years without reactions to a grown-in laparitimy gauze].

We report the remarkable history of a case with intraperitoneal retention of a gauze sponge, left in place for 24 years without any symptoms. The foreign body was removed in a selective operation after being detected by routine gynecologic examination. The rare and unusually fortunate course is discussed.

Female↗
PubMedDate not supplied

[Effectiveness of local prostaglandin instillations in tubal pregnancy in relation to preoperative beta-HCG level].

33 patients with tubal pregnancy and beta-HCG level less than 2500 mIU/ml were treated with local, laparoscopic Prostaglandin-injection. Re-operation was not necessary and beta-HCG fell to undetectable levels in 73% (p = 0.05). Serial beta-HCG correlated poorly with outcome. In patients with an increasing beta-HCG success was limited to 55% (p = 0.59). In contrast patients with falling or stable beta-HCG values had success rates of 85.7% (p = 0.22) and 83.5% (p = 0.30) respectively. Our data suggests there may be a clinical advantage to the use of prostaglandin-injection for the conservative management of early ectopic pregnancy. However the utility of preoperative serial beta-HCG values in predicting success showed a trend, without reaching statistical significance.

Abortifacient Agents, Nonsteroidal↗
PubMedDate not supplied

[Bilateral hydrothorax of the newborn infant].

Bilateral hydrothorax of the newborn is not compatible with life. It must, therefore, be diagnosed sonographically before birth and drained immediately following birth. The therapy which can be applied is discussed with reference to a case.

Adult↗
PubMedDate not supplied

[Risk of recurrence in HELLP syndrome].

The recurrence risk of HELLP-syndrome is reported to be between 2.6% and 24%. But yet, there are no accurate case reports about this topic available. In a retrospective study, 25 patients, which had suffered from a pre partum HELLP-syndrome, were interviewed about possible subsequent pregnancies. In 7 patients 8 pregnancies were found, which began between 5 and 55 months after the HELLP-syndrome. No recurrence of a HELLP-syndrome was observed in these 7 patients. Although in 71% a hypertension had been present during the HELLP-syndrome, only 1 patient had an elevated blood pressure in the subsequent pregnancy. Whilst all of the patients with HELLP-syndrome had been delivered by cesarean section, 50% of the patients were delivered vaginally in the subsequent pregnancy. There was no evidence of maternal or neonatal complications related to HELLP-syndrome. Nevertheless, even if the recurrence risk seems to be low, pregnancies after HELLP syndrome should be observed carefully.

Adult↗
PubMedDate not supplied

[Is there an intermittent HELLP syndrome?].

A case of an HELLP-syndrome in the 32nd week of gestation with complete remission of pathological biochemical data and clinical symptomatic within five days is reported. Twenty days later a Caesarean section because of severe fetal growth retardation was performed. Because of this case it has to be discussed, if an "intermittent" HELLP-syndrome does really exist?

Adult↗
PubMedDate not supplied

Primary neuroendocrine differentiated mucinous adenocarcinoma of the vulva: case report and review of the literature.

Only a few cases on mucinous adenocarcinomas of the vulva have been reported. In this study, we present a case of a 75-year-old woman with a tumor in the left major labium. Because biopsy had shown formations of squamous cell carcinoma, radical vulvectomy with bilateral inguinal and femoral lymph node dissection were performed. At that time, histology was interpreted as small-cell, anaplastic carcinoma, with focal epidermoid differentiation. Postoperative radiation therapy was performed. Sixteen months after surgery, the patient presented with bilateral breast carcinomas. Histology showed a scirrhous carcinoma of the left and a medullary carcinoma of the right breast, but no lymph node metastases. Histochemical and immunohistochemical re-examination of the vulvar carcinoma now revealed a mucinous adenocarcinoma with neuroendocrine differentiation. The tumor expressed neuroendocrine markers such as chromogranin A and protein gene-product (PGP) 9.5, as well as peptides of the vasoactive intestinal polypeptide (VIP) family, and serotonin. Histochemical silver stains demonstrated Grimelius argyrophilia and Masson argentaffinity. Because of positive estrogen and progesterone receptor status of both breast cancers, postoperative Tamoxifen therapy was performed. The patient is still alive four years after vulvectomy.

Adenocarcinoma, Mucinous↗
PubMedDate not supplied

Oral Anticoagulation in patients with gynecological cancer and radiotherapy: a retrospective analysis of 132 patients.

Venous thromboembolism is reported to be a leading cause of death and morbidity after surgery and during radiotherapy for gynecologic malignancies. This study was performed to evaluate the incidence of thromboembolism as well as the benefit and risk of its prophylaxis with coumarin in this patient selection. Between 1988 and 1992, 132 patients with gynecologic malignancies underwent postoperative or primary radiotherapy (53 patients without prior surgery). Heparin (5000 IU t.i.d., s.c.) was administered perioperatively, and coumarin (International normalized ratio = INR target 2.0-3.5) was given to all patients during radiotherapy. Daily visits for inspection of the legs and for possible symptoms and signs of thromboembolism were performed. In case of diagnostic doubts, impedance plethysmography and phlebography for diagnosis of venous thrombosis, and lung scanning for diagnosis of pulmonary embolism were performed. Among the 132 patients, 9 (6.8%) developed deep venous thrombosis of the renal vein and of the inferior caval vein occurred in one additional patient. Pulmonary embolism was detected in 5 patients (3.8%). All thromboembolic events were without lethal outcome. Bleeding episodes were observed in 7 patients (5.3%); in two of them a major bleeding led to cessation of coumarin administration. The prophylaxis of thromboembolism in gynecologic oncology with coumarin seems to be effective, safe and inexpensive.

Administration, Oral↗