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Biomedical subjects

A Squires

Publications and source records attributed to A Squires.

10 recordsLinked to original sources

The moving fire hydrant experiment: movement of objects to a new location reelicits marking in rats.

Three experiments were carried out to investigate the influence of object relocation on object marking in an open field by hooded and albino rats. Object marking was reelicited when an object was moved to a new location in the second half of an open field test. Control conditions revealed that an object briefly moved and returned to the original location elicited no more marking than a stationary object. The higher level of marking of the relocated object suggests that object marking may provide an index of spatial knowledge. The implication of spatial knowledge in controlling marking behavior is congruent with observations that rats with hippocampal damage show increased marking.

Animals↗

Teaching telemetry.

For patients on telemetry monitoring, knowledge is power--and comfort. You can develop informative tools to help critical care nurses put these patients at ease.

Adult↗

Within reach.

Learn how one rural community hospital overcame staffing and funding shortages to create a successful, collaborative orientation program for its critical care nurses.

Critical Care↗

Testosterone decreases CA1 plasticity in vivo in gonadectomized male rats.

Estrogen has been reported to enhance CA1 functional plasticity in adult rats, as measured by the induction of long-term potentiation (LTP). In the present study, the effects of androgens on CA1 LTP were assessed in adult male Sprague-Dawley rats in vivo following peripubertal castration. Castrated rats with cholesterol implants showed significantly greater plasticity, both in degree and duration of potentiation, than castrated rats given testosterone or dihydrotestosterone implants. An LTP paradigm reported to produce decremental LTP in vitro produced nondecremental LTP in androgen-deprived rats, but decremental LTP in androgen-treated rats. These results suggest that androgens, unlike estrogens, act to reduce CA1 plasticity in the adult rat.

Animals↗

Catecholamine concentrations in rat nasal mucus are modulated by trigeminal stimulation of the nasal cavity.

Olfactory mucus provides the perireceptor environment in which the initial steps of olfactory signal transduction occur [5]. Extrinsic autonomic and trigeminal innervation controls mucus secretion and may release neurotransmitters into nasal mucus [13]. We quantitated catecholamines in rat nasal mucus and found that catecholamine levels first increased and then declined with trigeminal stimulation. These data indicate that catecholamine levels are regulated in nasal mucus and could modulate the odor sensitivity of olfactory sensory neurons.

Animals↗

Beware of burnout.

Explore the source record for details and available documents.

Burnout, Professional↗

Teaching patients about telemetry.

For patients on telemetry monitoring, knowledge is power--and comfort. This article describes how two nurses developed informational materials to help busy nurses give patients the information they need to set their minds at rest about telemetry.

Heart Diseases↗