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Biomedical subjects

A Spira

Publications and source records attributed to A Spira.

167 records · Page 10Linked to original sources
PubMedDate not supplied

[Semen characteristics and fertility (author's transl)].

The semen characteristics of 215 fertile men (F = fathers requesting vasectomy) and of 409 infertile men (I) have been analysed under strictly identical conditions. The mean values for volume, sperm concentration, and the percentages of motile, vital and morphologically normal spermatozoa were greater in group F than in I. Seminal variations were much greater in cases of testicular lesions (cryptorchidism, hypotrophy) than in varicocele, although there remains a difference between F and I even after exclusion of all clinical lesions suggesting a role for other factors in the origin of much cases of infertility. Other than in cases of azoospermia, there is no difference in the function of the accessory glands detectable by the assay of seminal biochemical markers: fructose (seminal vesicles) acid phosphatase and citrate (prostate); only L-carnitine (epididymal marker) is elevated in the fertile men, however this difference is only a reflection of the observed difference in sperm concentration in combination with the close correlation between sperm concentration and L-carnitine values.

Acid Phosphatase↗
PubMedDate not supplied

Trends in sexual behavior. Analyse des Comportements Sexuels en France Investigators.

The definition of strategies for preventing STD and AIDS requires a better knowledge of sexual behavior in the general population and in specific subgroups of the population. Surveys have been undertaken in different countries to provide such information, and they allow to draw some general conclusions. Even if there exist a very important variability of sexual behaviors between individuals and within individuals in different situations, the primary characteristics of sexual behavior in different developed countries appear to be quite similar. All prevention efforts need to be directed toward everybody in the population, but they must in the same time be made age specific, gender specific, and culture specific. The repertoire of available methods must be expanded to offer different choices, taking into account important psychological and sociologic determinants of sexual behavior. The development of methods under women's control would permit to combine the goals of contraception and of STD prevention.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[Cancer of the ovary and the treatment of infertility. Analysis of the article by Whittemore et al].

Whittemore and al. recently published a general paper concerning the risk factors of ovarian cancer, combining the data from 12 epidemiological studies realised from 1979 to 1988. Three of these studies allowed to analyze the role of infertility treatments which were associated to an increased risk (odds ratio = 2.8), specially in nulligravid women (OR = 27.0). However potential bias could not be rejected, and information on drugs was too scanty, so that no definite conclusion could be drawn, even if the results were in accordance with the main physicopathogenical theories. In conclusion, it appears necessary to undertake a large epidemiological study, and, in the same time, even if patients must be reassured, to recommend attention to the doctors when prescribing infertility treatments.

Case-Control Studies↗
PubMedDate not supplied

Risk factors in men and women consulting for infertility.

In three regions of France, over a period of 1 year, we registered all couples (women and men) who have consulted and obtained a medical evaluation (medical causes and risk factors) for primary or secondary infertility. For women with secondary infertility caused by tubal disorders (compared to other causes) the risk factors are: STDs (RR = 7.5; 4.8-11.6); previous surgery, including appendectomy (RR = 4.7; 3.4-6.5); history of salpingitis (RR = 32.1; 18.8-55.3); and ectopic pregnancy (RR = 21.5; 11.4-41.3). For consulting men, secondary infertility risk factors are varicocele (RR = 4.1; 2.0-8.5) and previous genital infection (RR = 5.8; 2.8-11.7) for oligoteratosasthenospermia, and histories of major treatment or exposure to toxic agents such as X-rays, benzenes, or pesticides (RR = 6.6; 1.3-30.4) for secretory azoospermia. These results underline the importance for physicians of making a systematic exploration for all the different infertility risk factors in men and women, enabling greater control and effectiveness in medical diagnosis.

Cervix Mucus↗