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Biomedical subjects

A Spiliopoulos

Publications and source records attributed to A Spiliopoulos.

At least 109 records · Page 6Linked to original sources
PubMed1985

Tomographic imaging of the human thyroid with a positron camera before and after partial thyroidectomy.

A high-density avalanche chamber positron camera was used for tomographic imaging of the human thyroid before and after partial thyroidectomy. Images were made between 6 and 24 h after oral administration of the positron-emitting radionuclide, Na-124I with activities varying between 0.1 and 0.3 mCi before the surgical intervention and with activities between 0.03 and 0.05 mCi following partial thyroidectomy. The results of thyroid imaging performed on 50 patients and their surgical relevance are discussed; as an illustration, one typical case is presented. As a consequence of the high spatial resolution of the camera (2.5 mm full width at half maximum), the functional volume of the thyroid may be estimated from the transaxial tomographic sections before and following partial thyroidectomy, correct to about 10%. The thyroid surface, defined by the contours from each transaxial section, may be displayed using three-dimensional shaded-graphics techniques. This new imaging technique makes possible a fully three-dimensional description of the thyroid in vivo and contributes significantly to the surgical follow-up.

Goiter, Nodular↗
PubMed1985

[Thymomas].

Explore the source record for details and available documents.

Adolescent↗
PubMed1982

[[Clodronate therapy of hypercalcemia caused by hyperparathyroidism].

The diphosphonates, powerful agents which inhibit osteolysis, have been used parenterally with success to treat malignant hypercalcemia. 4 cases of anatomically confirmed primary hyperparathyroidism (age of patients 58-78 years) were admitted with a serum calcium of over 4 mmol/l in one case, over 3,5 mmol/l in a second case and over 3 mmol/l in the other two. The patients received an infusion of isotonic saline and dichloromethylene-diphosphonate (clodronate) parenterally in a dose of 500 mg a day. Serum calcium began to fall in all four patients 48 hours after the treatment was started. Intravenous clodronate therefore appears to be the treatment of choice for parathyroid crises and allows surgery of the adenomas in better metabolic conditions.

Aged↗
PubMed1981

Haemodialysis and hypothalamo-pituitary-testicular axis.

Disturbances in testicular function develop in uraemic patients, but the effect of haemodialysis on them has not been determined definitively. Because of this, 22 patients with chronic renal failure who were receiving regular dialysis treatment underwent studies of the hypothalamo-pituitary-testicular axis before, during and after a dialysis. On all these occasions, serum testosterone concentrations were lower than the values found in 26 normal men. In contrast, serum concentrations of FSH and LH were higher than normal. 13 of these patients showed a normal response of the hypothalamo-pituitary system to the clomiphene stimulation test and a diminished response of Leydig's cells to the human chorionic gonadotropin stimulation test. It is concluded that haemodialysis does not affect the impaired gonadal function of male uraemic patients.

Adult↗
PubMed1980

[Survival following surgery for bronchopulmonary cancer. Results after five years].

The authors study the actuarial survival of 253 primary bronchopulmonary cancers operated in Geneva between 1967 and 1976. The overall operative mortality was 9.88%. The overall survival of resections alone was 26.6% at 5 years. The small size of the tumor, the absence of mediastinal extension and an epidermoid histology are the best survival rate factors: 43.2% of stage I cases survive at 5 years against 4.86% of stage III cases. The accidental discovery of as asymptomatic tumor gives a hope of survival of 43.9% at 5 years. Yet again this demonstrates the importance of mass screening by radiophotography. Surgery thus maintains its central role in the treatment of this disease, whilst chemo-, radio- and immunotherapy have not yet revealed their full possibilities.

Adenocarcinoma↗
PubMed1980

[Ability of cadaver kidneys to recover].

The scarcity in brain death donors may impose to use kidneys from non-heart-beating donors. In this paper, we have studied the injuries due to warm in situ ischemia, we also propose a pretreatment to protect the kidneys before removal. We propose the use of intra-aortic catheter for flushing by a femoral surgical approach. Functional studies of these kidneys have been performed during 2 h normothermic ex-vivo perfusion and the recognized good organs have been successful reimplanted after 24 h of cold ischemia.

Adolescent↗
PubMed1980

[Stenotic peptic esophagitis following gastric intubation].

In the light of five personal observations and after review of the literature, we call the attention on the possible occurrence of stenosing peptic oesophagitis after a medical act as frequent as apparently innocuous as is a nasogastric tube. However, if the tube itself may play a role in the apparition of the peptic oesophagitis, the primordial favoring element seems to be an often unknown, preexisting hiatal hernia. Prevention and precocious anti-acid treatment are of indisputable usefulness and efficacity. The surgical act, if it takes place, must not only take care of the stenosis but, more importantly, of the reflux.

Child, Preschool↗
PubMed1980

[Twelve cases of pheochromocytoma].

Twelve cases of phaeochromocytoma have been recognized and operated at the Geneva Clinic. There has not been found any malignancy. In few cases, the diagnosis has been suspected and made on the basis of an atypical presentation (shock due to intratumoral hemorrhage).

Adolescent↗
PubMed1979

[Renal artery stenosis following kidney transplantation -- an avoidable complication?].

Many etiologies have been proposed for renal artery stenosis following renal transplantation. Incorrect operative technique is the most frequent cause, but the condition is often due to vascular parietal lesions resulting from traction on the vessels during removal of kidneys, which causes dislocation of arterial parietal structures. Such traction is inevitable if kidneys are removed separately due to difficulties arising during deep mobilization of the kidneys. Furthermore, this technique involves direct flushing into the renal artery, and this may cause damage to the intima due to the canula. Canula and traction are the major causes of stenosis. The authors present their own cases and propose that kidneys be removed "en bloc". This is the only way to prevent traction on vessels, and it permits flushing through the aorta for cooling.

Adult↗
PubMed1979

[Survival of operated bronchopulmonary neoplasms. Actuarial results after 5 years].

The actuarial survival of 253 primary bronchopulmonary cancer patients undergoing surgery in Geneva between 1967 and 1976 is studied. The overall post-surgical mortality was 9.88%. The overall survival after exclusion of patients without radical tumor excision was 26.6% at 5 years. The small size of the tumor, the absence of mediastinal extension and an epidermoid histology are the best survival rate factors: 43.2% of stage I patients survive at 5 years against 4.86% of stage III patients. The survival for asymptomatic tumors is 43.9% at 5 years. This suggests the importance of mass screening by radiophotography. Thus, surgery retains its central role in the treatment of this disease, whilst chemo-, radio- and immunotherapy have not yet realized their full potential.

Carcinoma, Bronchogenic↗
PubMed1979

[Esophageal leiomyomas. Apropos of 16 cases].

16 cases of oesophageal leiomyomas are reported; diagnostic difficulties and important surgical consequences are discussed. The surgical procedures must be as soon as possible, and should be enucleation of the lesion. The results are excellent. In three cases postoperative oesophageal spasms and retrosternal pains needed secondary medical treatment.

Adult↗
PubMed1979

[Breast cancer in males].

Until 1971 13 cases of breast cancer in men were observed in our service. In the world literature it accounts for 1% of all cancer of the breast; in our series we have found 4% of all breast cancer. Men present themselves for treatment later and with more advanced local signs than women. In our series, the greatest number of cases occurs near the seventies in men, which is about twenty years later than in women. The etiology is remained unknown, but Klinefelter's disease seems to be a risk for breast cancer. If there are no metastasis, we prefer in our service the surgical treatment as unique treatment. If possible the operation of Patey is realised, but sometimes we have to do a simple mastectomy only as a safe alternative for poor risk patient. In case of metastatic breast cancer the adjuvant treatment was X-ray therapy, chemotherapy and in some of our cases hormonotherapy. We do not have any experience with suppressive hormonal therapy such as orchiectomy or adrenalectomy. Most of the authors think that prognosis of breast cancer in males is worse than in women; the constant central localization of the tumour may be an explanation for that. The fate of women with central lesions is as poor as in males.

Aged↗