Search PubMed⌕ Search

Biomedical subjects

A Smialowski

Publications and source records attributed to A Smialowski.

20 records · Page 2Linked to original sources

The influence of cholinomimetics on bioelectric activity of rabbit's limbic system and behaviour.

The influence of acetylcholine, physostigmine, and carbachole administered systemically in aqueous solutions and the volume of 2 or 3 mul to dorsal hippocampus (DH) or basal amygdaloid nucleus (BA) on rabbit's EEG and behaviour in chronic experiment was examined. EEGs were recorded from anterior cingular gyrus, DH, BA and medial hypothalamus. The excitation or attack activities after the administered compounds and of the receptors sensitive to acetylcholine in DH and BA were stated. Moreover, a strong functional connection of DH and BA was observed.

Acetylcholine↗

The effect of apomorphine injection into caudate nucleus on electrical activity of some structures of the rabbit brain.

The studies were carried out on rabbits with chronically implanted electrodes and cannulas. Apomorphine, dopamine, or haloperidol were injected into the caudate nucleus of wakeful rabbits at a volume of 2 microliter. EEG was recorded from gyrus cinguli anterior, nucleus dorsalis raphe, and dorsal part of hippocampal formation. Apomorhine produced a dose-dependent desynchronization of EEG in the structure tested. This effect did not appear when dopaminergic receptors were blocked by previous systemic (1.2 mg/kg) or intracaudal (10microgram) injection of heloperidol.

Animals↗